1PVQ

BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7

Summary for 1PVQ

Related1KBU 1MA7 1CRX 3CRX 1NZB 1OUQ 1F44 1PVP 1PVR
Descriptor34-MER, Recombinase CRE, ... (4 entities in total)
Functional Keywordscre, recombinase, dna, cre-loxp recombination, recombination-dna complex, recombination/dna
Biological sourceEnterobacteria phage P1
Total number of polymer chains4
Total molecular weight99354.2
Authors
Baldwin, E.P.,Martin, S.S.,Abel, J.,Gelato, K.A.,Kim, H.,Schultz, P.G.,Santoro, S.W. (deposition date: 2003-06-28, release date: 2004-02-17, Last modification date: 2012-02-01)
Primary citation
Baldwin, E.P.,Martin, S.S.,Abel, J.,Gelato, K.A.,Kim, H.,Schultz, P.G.,Santoro, S.W.
A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10:1085-1094, 2003
PubMed: 14652076 (PDB entries with the same primary citation)
DOI: 10.1016/j.chembiol.2003.10.015
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.75 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.266444.6%21.8%5.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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