1PVR
BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE LOXP (WILDTYPE) RECOGNITION SITE
Summary for 1PVR
Entry DOI | 10.2210/pdb1pvr/pdb |
Related | 1CRX 1F44 1KBU 1MA7 1NZB 1OUQ 1PVP 1PVQ 3CRX 4CRX |
Descriptor | 34-MER, Recombinase CRE, ... (4 entities in total) |
Functional Keywords | cre, recombinase, dna, cre-loxp recombination, recombination-dna complex, recombination/dna |
Biological source | Enterobacteria phage P1 |
Total number of polymer chains | 4 |
Total formula weight | 99356.17 |
Authors | Baldwin, E.P.,Martin, S.S.,Abel, J.,Gelato, K.A.,Kim, H.,Schultz, P.G.,Santoro, S.W. (deposition date: 2003-06-28, release date: 2004-02-17, Last modification date: 2023-08-16) |
Primary citation | Baldwin, E.P.,Martin, S.S.,Abel, J.,Gelato, K.A.,Kim, H.,Schultz, P.G.,Santoro, S.W. A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water. Chem.Biol., 10:1085-1094, 2003 Cited by PubMed: 14652076DOI: 10.1016/j.chembiol.2003.10.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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