1PVR

BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE LOXP (WILDTYPE) RECOGNITION SITE

Summary for 1PVR

Entry DOI	10.2210/pdb1pvr/pdb
Related	1CRX 1F44 1KBU 1MA7 1NZB 1OUQ 1PVP 1PVQ 3CRX 4CRX
Descriptor	34-MER, Recombinase CRE, ... (4 entities in total)
Functional Keywords	cre, recombinase, dna, cre-loxp recombination, recombination-dna complex, recombination/dna
Biological source	Enterobacteria phage P1
Total number of polymer chains	4
Total formula weight	99356.17
Authors	Baldwin, E.P.,Martin, S.S.,Abel, J.,Gelato, K.A.,Kim, H.,Schultz, P.G.,Santoro, S.W. (deposition date: 2003-06-28, release date: 2004-02-17, Last modification date: 2023-08-16)
Primary citation	Baldwin, E.P.,Martin, S.S.,Abel, J.,Gelato, K.A.,Kim, H.,Schultz, P.G.,Santoro, S.W. A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water. Chem.Biol., 10:1085-1094, 2003 Cited by PubMed: 14652076 DOI: 10.1016/j.chembiol.2003.10.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation