2PIS

Efforts toward Expansion of the Genetic Alphabet: Structure and Replication of Unnatural Base Pairs

Summary for 2PIS

• Entry DOI: 10.2210/pdb2pis/pdb
• Descriptor: DNA (5'-D(*CP*GP*(CBR)P*GP*AP*AP*(FFD)P*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION (2 entities in total)
• Functional Keywords: nucleic acid, duplex, replication, unnatural base, dna
• Total number of polymer chains: 12
• Total formula weight: 48343.47

Authors

Matsuda, S.,Fillo, J.D.,Henry, A.A.,Wilkins, S.J.,Rai, P.,Dwyer, T.J.,Geierstanger, B.H.,Wemmer, D.E.,Schultz, P.G.,Spraggon, G.,Romesberg, F.E. (deposition date: 2007-04-13, release date: 2007-10-30, Last modification date: 2024-02-21)

• Primary citation: Matsuda, S.,Fillo, J.D.,Henry, A.A.,Rai, P.,Wilkens, S.J.,Dwyer, T.J.,Geierstanger, B.H.,Wemmer, D.E.,Schultz, P.G.,Spraggon, G.,Romesberg, F.E.; Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs.; J.Am.Chem.Soc., 129:10466-10473, 2007; PubMed: 17685517; DOI: 10.1021/ja072276d

Experimental method

X-RAY DIFFRACTION (2.8 Å)