2PW8
Crystal structure of sulfo-hirudin complexed to thrombin
Summary for 2PW8
Entry DOI | 10.2210/pdb2pw8/pdb |
Related | 4HTC |
Descriptor | Thrombin light chain, Thrombin heavy chain, Hirudin variant-1, ... (6 entities in total) |
Functional Keywords | thrombin, hirudin, sulfotyrosine, hydrolase |
Biological source | Hirudo medicinalis (medicinal leech) More |
Cellular location | Secreted, extracellular space: P00734 P00734 Secreted: P01050 |
Total number of polymer chains | 3 |
Total formula weight | 39990.98 |
Authors | Liu, C.C.,Brustad, E.,Liu, W.,Schultz, P.G. (deposition date: 2007-05-10, release date: 2007-08-21, Last modification date: 2023-11-15) |
Primary citation | Liu, C.C.,Brustad, E.,Liu, W.,Schultz, P.G. Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin. J.Am.Chem.Soc., 129:10648-10649, 2007 Cited by PubMed: 17685615DOI: 10.1021/ja0735002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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