2PW8
Crystal structure of sulfo-hirudin complexed to thrombin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | L | Thrombin light chain | polymer | 27 | 3188.6 | 1 | UniProt (P00734) Pfam (PF09396) In PDB | Homo sapiens (human) | |
2 | H | Thrombin heavy chain | polymer | 258 | 29651.1 | 1 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (human) | |
3 | I | Hirudin variant-1 | polymer | 65 | 7069.6 | 1 | UniProt (P01050) Pfam (PF00713) In PDB | Hirudo medicinalis (medicinal leech) | Lepirudin |
4 | L | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
5 | H | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
6 | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
I: 3 - 65 (UniProt: P01050)
PDB | External Database | Details |
---|---|---|
Leu 1 | - | expression tag |
Thr 2 | - | expression tag |
Tys 63 | Tyr 63 | modified residue |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 39909.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 81.7 | |
All* | Total formula weight | 39991.0 |