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4XZ9
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BU of 4xz9 by Molmil
Transaldolase variant E60Q/F132Y from T. acidophilum in complex with DHA Schiff base and G3P
分子名称: 1,3-PROPANDIOL, ACETATE ION, GLYCEROL, ...
著者Sautner, V, Tittmann, K.
登録日2015-02-04
公開日2015-09-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Converting Transaldolase into Aldolase through Swapping of the Multifunctional Acid-Base Catalyst: Common and Divergent Catalytic Principles in F6P Aldolase and Transaldolase.
Biochemistry, 54, 2015
6YR3
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BU of 6yr3 by Molmil
1.48 Angstrom Resolution Crystal Structure of Transaldolase from Thermoplasma acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate
分子名称: ACETATE ION, FRUCTOSE -6-PHOSPHATE, GLYCEROL, ...
著者Sautner, V, Tittmann, K.
登録日2020-04-19
公開日2021-04-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release
To Be Published
6YRH
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BU of 6yrh by Molmil
Transaldolase variant T30C/D211C from T. acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate
分子名称: ACETATE ION, FRUCTOSE -6-PHOSPHATE, GLYCEROL, ...
著者Sautner, V, Lietzow, T.H, Tittmann, K.
登録日2020-04-20
公開日2021-05-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release
To Be Published
6YRT
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BU of 6yrt by Molmil
Transaldolase variant T30D from T. acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate
分子名称: ACETATE ION, FRUCTOSE -6-PHOSPHATE, GLYCEROL, ...
著者Sautner, V, Klaus, M, Tittmann, K.
登録日2020-04-20
公開日2021-05-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release
To Be Published
6YRE
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BU of 6yre by Molmil
Transaldolase variant T30C/D211C from T. acidophilum
分子名称: ACETATE ION, GLYCEROL, Probable transaldolase
著者Sautner, V, Lietzow, T.H, Tittmann, K.
登録日2020-04-20
公開日2021-05-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release
To Be Published
6YS0
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BU of 6ys0 by Molmil
Transaldolase variant D211A from T. acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate
分子名称: ACETATE ION, FRUCTOSE -6-PHOSPHATE, GLYCEROL, ...
著者Sautner, V, Klaus, M, Tittmann, K.
登録日2020-04-20
公開日2021-05-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release
To Be Published
6YRM
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BU of 6yrm by Molmil
Transaldolase variant T30A from T. acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate
分子名称: ACETATE ION, FRUCTOSE -6-PHOSPHATE, GLYCEROL, ...
著者Sautner, V, Klaus, M, Tittmann, K.
登録日2020-04-20
公開日2021-05-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release
To Be Published
6Y4D
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BU of 6y4d by Molmil
Crystal structure of a short-chain dehydrogenase/reductase (SDR) from Zephyranthes treatiae in complex with NADP+
分子名称: GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, short-chain dehydrogenase/reductase (SDR)
著者Sautner, V, Steimle, S, Roth, S, Mueller, M, Tittmann, K.
登録日2020-02-20
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crossing the Border: From Keto- to Imine Reduction in Short-Chain Dehydrogenases/Reductases.
Chembiochem, 21, 2020
6ZX4
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BU of 6zx4 by Molmil
Neisseria gonorrhoeae transaldolase
分子名称: CITRIC ACID, GLYCEROL, Transaldolase
著者Sautner, V, Rabe von Pappenheim, F, Wensien, M, Tittmann, K.
登録日2020-07-29
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.96 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6YJY
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BU of 6yjy by Molmil
Crystal structure of human glutaminyl cyclase in complex with neurotensin 1-5
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTAMINE, Glutaminyl-peptide cyclotransferase, ...
著者Funk, L.M, Sautner, V, Tittmann, K.
登録日2020-04-05
公開日2020-07-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease.
Biochemistry, 59, 2020
6YI1
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BU of 6yi1 by Molmil
Crystal structure of human glutaminyl cyclase in complex with Glu(gamma-hydrazide)-Phe-Ala
分子名称: 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ...
著者Kupski, O, Sautner, V, Tittmann, K.
登録日2020-03-31
公開日2020-07-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease.
Biochemistry, 59, 2020
6HAF
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BU of 6haf by Molmil
Pyruvate oxidase variant E59Q from L. plantarum in complex with phosphate
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ...
著者Funk, L.M, Sautner, V, Tittmann, K.
登録日2018-08-07
公開日2019-08-21
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Low-barrier hydrogen bonds in enzyme cooperativity.
Nature, 573, 2019
6HAD
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BU of 6had by Molmil
Human transketolase variant E160Q
分子名称: CALCIUM ION, MAGNESIUM ION, SODIUM ION, ...
著者Dai, S, Sautner, V, Tittmann, K.
登録日2018-08-07
公開日2019-08-21
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献Low-barrier hydrogen bonds in enzyme cooperativity.
Nature, 573, 2019
6HA3
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BU of 6ha3 by Molmil
Human transketolase variant E160Q in covalent complex with donor ketose D-fructose-6-phosphate
分子名称: 1,2-ETHANEDIOL, 2-C-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium-2-yl}-6-O-phosphono-D-glucitol, CALCIUM ION, ...
著者Dai, S, Sautner, V, Tittmann, K.
登録日2018-08-07
公開日2019-08-21
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Low-barrier hydrogen bonds in enzyme cooperativity.
Nature, 573, 2019
6QL5
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BU of 6ql5 by Molmil
Structure of fatty acid synthase complex with bound gamma subunit from Saccharomyces cerevisiae at 2.8 angstrom
分子名称: 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
著者Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A.
登録日2019-01-31
公開日2020-03-18
最終更新日2020-04-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
6QL6
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BU of 6ql6 by Molmil
Structure of Fatty acid synthase complex from Saccharomyces cerevisiae at 2.9 Angstrom
分子名称: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, ...
著者Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A.
登録日2019-01-31
公開日2020-03-18
最終更新日2020-04-08
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
6QL9
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BU of 6ql9 by Molmil
Structure of Fatty acid synthase complex from Saccharomyces cerevisiae at 2.9 Angstrom
分子名称: 1,2-ETHANEDIOL, 4'-PHOSPHOPANTETHEINE, ACETATE ION, ...
著者Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A.
登録日2019-01-31
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
6QL7
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BU of 6ql7 by Molmil
Structure of fatty acid synthase complex with bound gamma subunit from Saccharomyces cerevisiae at 4.6 angstrom
分子名称: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, Translation machinery-associated protein 17
著者Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A.
登録日2019-01-31
公開日2020-03-18
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (4.6 Å)
主引用文献Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
6ZWJ
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BU of 6zwj by Molmil
Neisseria gonorrhoeae transaldolase at 1.35 Angstrom resolution
分子名称: CITRIC ACID, GLYCEROL, Transaldolase
著者Rabe von Pappenheim, F, Wensien, M, Sautner, V, Tittmann, K.
登録日2020-07-28
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6ZWF
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BU of 6zwf by Molmil
Neisseria gonorrhoeae transaldolase
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, CITRIC ACID, ...
著者Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K.
登録日2020-07-28
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6ZWH
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BU of 6zwh by Molmil
Neisseria gonorrhoeae transaldolase at 1.5 Angstrom resolution
分子名称: 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ...
著者Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K.
登録日2020-07-28
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
7BBW
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BU of 7bbw by Molmil
Neisseria gonorrhoeae transaldolase, variant C38S
分子名称: GLYCEROL, Transaldolase
著者Rabe von Pappenheim, F, Wensien, M, Tittmann, K.
登録日2020-12-18
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
7BBX
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BU of 7bbx by Molmil
Neisseria gonorrhoeae transaldolase, variant K8A
分子名称: 1,2-ETHANEDIOL, CITRIC ACID, Transaldolase
著者Rabe von Pappenheim, F, Wensien, M, Funk, L.M, Tittmann, K.
登録日2020-12-18
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.85 Å)
主引用文献A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6RJC
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BU of 6rjc by Molmil
E.coli transketolase apoenzyme
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ...
著者Rabe von Pappenheim, F, Tittmann, K.
登録日2019-04-26
公開日2019-09-11
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Low-barrier hydrogen bonds in enzyme cooperativity.
Nature, 573, 2019
6RJB
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BU of 6rjb by Molmil
Human transketolase variant T382E
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Rabe von Pappenheim, F, Tittmann, K.
登録日2019-04-26
公開日2019-09-11
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Low-barrier hydrogen bonds in enzyme cooperativity.
Nature, 573, 2019

 

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