4DAU
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1Z2C
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![BU of 1z2c by Molmil](/molmil-images/mine/1z2c) | Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP | 分子名称: | Diaphanous protein homolog 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Rose, R, Weyand, M, Lammers, M, Ishizaki, T, Ahmadian, M.R, Wittinghofer, A. | 登録日 | 2005-03-08 | 公開日 | 2005-05-10 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural and mechanistic insights into the interaction between Rho and mammalian Dia. Nature, 435, 2005
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4DAT
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1WPW
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![BU of 1wpw by Molmil](/molmil-images/mine/1wpw) | Crystal Structure of IPMDH from Sulfolobus tokodaii | 分子名称: | 3-isopropylmalate dehydrogenase, MAGNESIUM ION | 著者 | Hirose, R, Sakurai, M, Suzuki, T, Moriyama, H, Sato, T, Yamagishi, A, Oshima, T, Tanaka, N. | 登録日 | 2004-09-14 | 公開日 | 2004-10-05 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of IPMDH from Sulfolobus tokodaii To be Published
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1IZ9
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![BU of 1iz9 by Molmil](/molmil-images/mine/1iz9) | Crystal Structure of Malate Dehydrogenase from Thermus thermophilus HB8 | 分子名称: | MALATE DEHYDROGENASE | 著者 | Hirose, R, Hasegawa, T, Yamano, A, Kuramitsu, S, Hamada, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-10-01 | 公開日 | 2002-10-16 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Malate Dehydrogenase from Thermus themrophilus HB8 To be published
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3M51
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![BU of 3m51 by Molmil](/molmil-images/mine/3m51) | Structure of the 14-3-3/PMA2 complex stabilized by Pyrrolidone1 | 分子名称: | 14-3-3-like protein C, 2-hydroxy-5-[(5S)-3-hydroxy-5-(4-nitrophenyl)-2-oxo-4-(phenylcarbonyl)-2,5-dihydro-1H-pyrrol-1-yl]benzoic acid, N.plumbaginifolia H+-translocating ATPase mRNA | 著者 | Ottmann, C, Rose, R, Waldmann, H. | 登録日 | 2010-03-12 | 公開日 | 2010-05-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Identification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactions Angew.Chem.Int.Ed.Engl., 49, 2010
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3M50
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![BU of 3m50 by Molmil](/molmil-images/mine/3m50) | Structure of the 14-3-3/PMA2 complex stabilized by Epibestatin | 分子名称: | 14-3-3-like protein C, N-[(2R,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]-L-leucine, N.plumbaginifolia H+-translocating ATPase mRNA | 著者 | Ottmann, C, Rose, R, Waldmann, H. | 登録日 | 2010-03-12 | 公開日 | 2010-05-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Identification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactions Angew.Chem.Int.Ed.Engl., 49, 2010
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3I6S
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![BU of 3i6s by Molmil](/molmil-images/mine/3i6s) | Crystal Structure of the plant subtilisin-like protease SBT3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Subtilisin-like protease, alpha-L-fucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Rose, R, Ottmann, C. | 登録日 | 2009-07-07 | 公開日 | 2010-01-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for Ca2+-independence and activation by homodimerization of tomato subtilase 3. Proc.Natl.Acad.Sci.USA, 106, 2009
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3I74
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6YOA
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![BU of 6yoa by Molmil](/molmil-images/mine/6yoa) | Lig v 1 structure and the inflammatory response to the Ole e 1 protein family | 分子名称: | Major pollen allergen Lig v 1, NICKEL (II) ION | 著者 | Robledo-Retana, T, Bradley-Clark, J, Croll, T, Rose, R, Stagg, A, Villalba, M, Pickersgill, R. | 登録日 | 2020-04-14 | 公開日 | 2020-05-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | Lig v 1 structure and the inflammatory response to the Ole e 1 protein family. Allergy, 75, 2020
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3O8I
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![BU of 3o8i by Molmil](/molmil-images/mine/3o8i) | Structure of 14-3-3 isoform sigma in complex with a C-Raf1 peptide and a stabilizing small molecule fragment | 分子名称: | 14-3-3 binding site peptide of RAF proto-oncogene serine/threonine-protein kinase, 14-3-3 protein sigma, 6,6-dihydroxy-1-methoxyhexan-2-one | 著者 | Ottmann, C, Rose, R, Kaiser, M, Kuhenne, P. | 登録日 | 2010-08-03 | 公開日 | 2010-09-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling Mol.Cell.Biol., 30, 2010
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4DX0
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![BU of 4dx0 by Molmil](/molmil-images/mine/4dx0) | Structure of the 14-3-3/PMA2 complex stabilized by a pyrazole derivative | 分子名称: | 14-3-3-like protein E, 4-[(4R)-4-(4-nitrophenyl)-6-oxidanylidene-3-phenyl-1,4-dihydropyrrolo[3,4-c]pyrazol-5-yl]benzoic acid, N.plumbaginifolia H+-translocating ATPase mRNA | 著者 | Richter, A, Rose, R, Hedberg, C, Waldmann, H, Ottmann, C. | 登録日 | 2012-02-27 | 公開日 | 2012-05-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | An Optimised Small-Molecule Stabiliser of the 14-3-3-PMA2 Protein-Protein Interaction. Chemistry, 18, 2012
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3UBW
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![BU of 3ubw by Molmil](/molmil-images/mine/3ubw) | Complex of 14-3-3 isoform epsilon, a Mlf1 phosphopeptide and a small fragment hit from a FBDD screen | 分子名称: | (3S)-pyrrolidin-3-ol, 14-3-3 protein epsilon, Myeloid leukemia factor 1, ... | 著者 | Molzan, M, Weyand, M, Rose, R, Ottmann, C. | 登録日 | 2011-10-25 | 公開日 | 2012-01-25 | 最終更新日 | 2012-02-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural insights of the MLF1/14-3-3 interaction. Febs J., 279, 2012
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4J26
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![BU of 4j26 by Molmil](/molmil-images/mine/4j26) | Estrogen Receptor in complex with proline-flanked LXXLL peptides | 分子名称: | 12-mer Peptide, ESTRADIOL, Estrogen receptor beta | 著者 | Fuchs, S, Nguyen, H.D, Phan, T, Burton, M, Nieto, L, de Vries-van Leeuwen, I, Schmidt, A, Goodarzifard, M, Agten, S, Rose, R, Ottmann, C, Milroy, L.G, Brunsveld, L. | 登録日 | 2013-02-04 | 公開日 | 2013-03-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Proline primed helix length as a modulator of the nuclear receptor-coactivator interaction J.Am.Chem.Soc., 135, 2013
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4J24
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![BU of 4j24 by Molmil](/molmil-images/mine/4j24) | Estrogen Receptor in complex with proline-flanked LXXLL peptides | 分子名称: | 19-mer peptide, ESTRADIOL, Estrogen receptor beta | 著者 | Fuchs, S, Nguyen, H.D, Phan, T, Burton, M, Nieto, L, de Vries-van Leeuwen, I, Schmidt, A, Goodarzifard, M, Agten, S, Rose, R, Ottmann, C, Milroy, L.G, Brunsveld, L. | 登録日 | 2013-02-04 | 公開日 | 2013-03-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Proline primed helix length as a modulator of the nuclear receptor-coactivator interaction J.Am.Chem.Soc., 135, 2013
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3KUO
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![BU of 3kuo by Molmil](/molmil-images/mine/3kuo) | X-ray structure of the metcyano form of dehaloperoxidase from amphitrite ornata: evidence for photoreductive lysis of iron-cyanide bond | 分子名称: | CYANIDE ION, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Serrano, V.S, Chen, Z, Gaff, J.F, Rose, R, Franzen, S. | 登録日 | 2009-11-27 | 公開日 | 2010-06-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | X-ray structure of the metcyano form of dehaloperoxidase from Amphitrite ornata: evidence for photoreductive dissociation of the iron-cyanide bond. Acta Crystallogr.,Sect.D, 66, 2010
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3KUN
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![BU of 3kun by Molmil](/molmil-images/mine/3kun) | X-ray structure of the metcyano form of dehaloperoxidase from amphitrite ornata: evidence for photoreductive lysis of iron-cyanide bond | 分子名称: | CYANIDE ION, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Serrano, V.S, Chen, Z, Gaff, J.F, Rose, R, Franzen, S. | 登録日 | 2009-11-27 | 公開日 | 2010-06-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | X-ray structure of the metcyano form of dehaloperoxidase from Amphitrite ornata: evidence for photoreductive dissociation of the iron-cyanide bond. Acta Crystallogr.,Sect.D, 66, 2010
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3MHR
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![BU of 3mhr by Molmil](/molmil-images/mine/3mhr) | 14-3-3 sigma in complex with YAP pS127-peptide | 分子名称: | 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... | 著者 | Schumacher, B, Skwarczynska, M, Rose, R, Ottmann, C. | 登録日 | 2010-04-08 | 公開日 | 2010-09-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Structure of a 14-3-3[sigma]-YAP phosphopeptide complex at 1.15 A resolution Acta Crystallogr.,Sect.F, 66, 2010
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3OMO
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![BU of 3omo by Molmil](/molmil-images/mine/3omo) | Fragment-Based Design of novel Estrogen Receptor Ligands | 分子名称: | 2-(trifluoroacetyl)-1,2,3,4-tetrahydroisoquinolin-6-ol, Estrogen receptor beta, Nuclear receptor coactivator 1 | 著者 | Moecklinghoff, S, van Otterlo, W.A, Rose, R, Fuchs, S, Dominguez Seoane, M, Waldmann, H, Ottmann, C, Brunsveld, L. | 登録日 | 2010-08-27 | 公開日 | 2011-03-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Design and Evaluation of Fragment-Like Estrogen Receptor Tetrahydroisoquinoline Ligands from a Scaffold-Detection Approach. J.Med.Chem., 54, 2011
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3OLS
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![BU of 3ols by Molmil](/molmil-images/mine/3ols) | Crystal structure of estrogen receptor beta ligand binding domain | 分子名称: | ESTRADIOL, Estrogen receptor beta, Nuclear receptor coactivator 1 | 著者 | Moecklinghoff, S, Rose, R, Carraz, M, Visser, A, Ottmann, C, Brunsveld, L. | 登録日 | 2010-08-26 | 公開日 | 2010-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Synthesis and crystal structure of a phosphorylated estrogen receptor ligand binding domain. Chembiochem, 11, 2010
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3OMQ
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![BU of 3omq by Molmil](/molmil-images/mine/3omq) | Fragment-Based Design of novel Estrogen Receptor Ligands | 分子名称: | 2-[(trifluoromethyl)sulfonyl]-1,2,3,4-tetrahydroisoquinolin-6-ol, Estrogen receptor beta, Nuclear receptor coactivator 1 | 著者 | Moecklinghoff, S, van Otterlo, W.A, Rose, R, Fuchs, S, Dominguez Seoane, M, Waldmann, H, Ottmann, C, Brunsveld, L. | 登録日 | 2010-08-27 | 公開日 | 2011-03-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Design and Evaluation of Fragment-Like Estrogen Receptor Tetrahydroisoquinoline Ligands from a Scaffold-Detection Approach. J.Med.Chem., 54, 2011
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3OLL
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![BU of 3oll by Molmil](/molmil-images/mine/3oll) | Crystal structure of phosphorylated estrogen receptor beta ligand binding domain | 分子名称: | ESTRADIOL, Estrogen receptor beta, Nuclear receptor coactivator 1 | 著者 | Moecklinghoff, S, Rose, R, Ottmann, C, Brunsveld, L. | 登録日 | 2010-08-26 | 公開日 | 2010-11-17 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Synthesis and crystal structure of a phosphorylated estrogen receptor ligand binding domain. Chembiochem, 11, 2010
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3OMP
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![BU of 3omp by Molmil](/molmil-images/mine/3omp) | Fragment-Based Design of novel Estrogen Receptor Ligands | 分子名称: | 2-(trifluoroacetyl)-1,2,3,4-tetrahydroisoquinolin-7-ol, Estrogen receptor beta, Nuclear receptor coactivator 1 | 著者 | Moecklinghoff, S, van Otterlo, W.A, Rose, R, Fuchs, S, Dominguez Seoane, M, Waldmann, H, Ottmann, C, Brunsveld, L. | 登録日 | 2010-08-27 | 公開日 | 2011-03-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Design and Evaluation of Fragment-Like Estrogen Receptor Tetrahydroisoquinoline Ligands from a Scaffold-Detection Approach. J.Med.Chem., 54, 2011
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2BAP
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7TQL
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![BU of 7tql by Molmil](/molmil-images/mine/7tql) | CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B. | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Lapointe, C.P, Grosely, R, Sokabe, M, Alvarado, C, Wang, J, Montabana, E, Villa, N, Shin, B, Dever, T, Fraser, C, Fernandez, I.S, Puglisi, J.D. | 登録日 | 2022-01-26 | 公開日 | 2022-04-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. Nature, 607, 2022
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