4J26

Estrogen Receptor in complex with proline-flanked LXXLL peptides

Summary for 4J26

Entry DOI	10.2210/pdb4j26/pdb
Related	3OLL 4J24
Descriptor	Estrogen receptor beta, 12-mer Peptide, ESTRADIOL, ... (4 entities in total)
Functional Keywords	estrogen receptor, proline, lxxll, alpha-helix, structure stabilization, hormone receptor-peptide complex, hormone receptor/peptide
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: Q92731
Total number of polymer chains	4
Total formula weight	57672.62
Authors	Fuchs, S.,Nguyen, H.D.,Phan, T.,Burton, M.,Nieto, L.,de Vries-van Leeuwen, I.,Schmidt, A.,Goodarzifard, M.,Agten, S.,Rose, R.,Ottmann, C.,Milroy, L.G.,Brunsveld, L. (deposition date: 2013-02-04, release date: 2013-03-13, Last modification date: 2023-11-08)
Primary citation	Fuchs, S.,Nguyen, H.D.,Phan, T.T.,Burton, M.F.,Nieto, L.,de Vries-van Leeuwen, I.J.,Schmidt, A.,Goodarzifard, M.,Agten, S.M.,Rose, R.,Ottmann, C.,Milroy, L.G.,Brunsveld, L. Proline primed helix length as a modulator of the nuclear receptor-coactivator interaction J.Am.Chem.Soc., 135:4364-4371, 2013 Cited by PubMed: 23437920 DOI: 10.1021/ja311748r PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation