3Q4F
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5HMO
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5HMP
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![BU of 5hmp by Molmil](/molmil-images/mine/5hmp) | Myosin Vc pre-powerstroke state | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, ... | 著者 | Ropars, V, Pylypenko, O, Sweeney, H.L, Houdusse, A. | 登録日 | 2016-01-16 | 公開日 | 2016-09-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | 主引用文献 | The myosin X motor is optimized for movement on actin bundles. Nat Commun, 7, 2016
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4ZG4
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![BU of 4zg4 by Molmil](/molmil-images/mine/4zg4) | Myosin Vc Pre-powerstroke | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ropars, V, Pylypenko, O, Sweeney, L, Houdusse, A. | 登録日 | 2015-04-22 | 公開日 | 2016-03-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Force-producing ADP state of myosin bound to actin. Proc.Natl.Acad.Sci.USA, 113, 2016
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8BV1
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![BU of 8bv1 by Molmil](/molmil-images/mine/8bv1) | Peptide inhibitor P4 in complex with ASF1 histone chaperone | 分子名称: | GLYCEROL, Histone chaperone ASF1A, P4 peptide inhibitor of histone chaperone ASF1 | 著者 | Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G. | 登録日 | 2022-12-01 | 公開日 | 2023-07-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.834 Å) | 主引用文献 | Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach. Chem.Commun.(Camb.), 59, 2023
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4ANJ
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![BU of 4anj by Molmil](/molmil-images/mine/4anj) | MYOSIN VI (MDinsert2-GFP fusion) PRE-POWERSTROKE STATE (MG.ADP.AlF4) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CALMODULIN, ... | 著者 | Menetrey, J, Isabet, T, Ropars, V, Mukherjea, M, Pylypenko, O, Liu, X, Perez, J, Vachette, P, Sweeney, H.L, Houdusse, A.M. | 登録日 | 2012-03-19 | 公開日 | 2012-10-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin Vi. Mol.Cell, 48, 2012
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7ABM
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![BU of 7abm by Molmil](/molmil-images/mine/7abm) | X-ray structure of phosphorylated Barrier-to-autointegration factor (BAF) | 分子名称: | Barrier-to-autointegration factor, CESIUM ION | 著者 | Zinn-Justin, S, Marcelot, A, Le Du, M.H, Ropars, V. | 登録日 | 2020-09-08 | 公開日 | 2021-07-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.004 Å) | 主引用文献 | Di-phosphorylated BAF shows altered structural dynamics and binding to DNA, but interacts with its nuclear envelope partners. Nucleic Acids Res., 49, 2021
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6RMN
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![BU of 6rmn by Molmil](/molmil-images/mine/6rmn) | DNA mismatch repair proteins MLH1 and MLH3 | 分子名称: | DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION | 著者 | Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. | 登録日 | 2019-05-07 | 公開日 | 2021-05-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation. Proc.Natl.Acad.Sci.USA, 118, 2021
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6SHX
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![BU of 6shx by Molmil](/molmil-images/mine/6shx) | DNA mismatch repair proteins MLH1 and MLH3 | 分子名称: | DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION | 著者 | Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. | 登録日 | 2019-08-08 | 公開日 | 2021-05-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation. Proc.Natl.Acad.Sci.USA, 118, 2021
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6SNS
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![BU of 6sns by Molmil](/molmil-images/mine/6sns) | DNA mismatch repair proteins MLH1 and MLH3 | 分子名称: | DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION | 著者 | Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. | 登録日 | 2019-08-27 | 公開日 | 2021-05-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation. Proc.Natl.Acad.Sci.USA, 118, 2021
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6SNV
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![BU of 6snv by Molmil](/molmil-images/mine/6snv) | DNA mismatch repair proteins MLH1 and MLH3 | 分子名称: | DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION | 著者 | Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. | 登録日 | 2019-08-27 | 公開日 | 2021-05-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation. Proc.Natl.Acad.Sci.USA, 118, 2021
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6GY2
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8CJ3
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![BU of 8cj3 by Molmil](/molmil-images/mine/8cj3) | Urea-based foldamer inhibitor c3u_7 chimera in complex with ASF1 histone chaperone | 分子名称: | Histone chaperone ASF1A, c3u_7 chimera inhibitor of histone chaperone ASF1 | 著者 | Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G. | 登録日 | 2023-02-11 | 公開日 | 2023-07-05 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach. Chem.Commun.(Camb.), 59, 2023
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8CJ2
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![BU of 8cj2 by Molmil](/molmil-images/mine/8cj2) | Urea-based foldamer inhibitor c3u_5 chimera in complex with ASF1 histone chaperone | 分子名称: | GLYCEROL, Histone chaperone ASF1A, SULFATE ION, ... | 著者 | Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G. | 登録日 | 2023-02-11 | 公開日 | 2023-07-05 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.127 Å) | 主引用文献 | Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach. Chem.Commun.(Camb.), 59, 2023
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8CJ1
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![BU of 8cj1 by Molmil](/molmil-images/mine/8cj1) | Urea-based foldamer inhibitor c3u_3 chimera in complex with ASF1 histone chaperone | 分子名称: | Histone chaperone ASF1A, c3u_3 chimera inhibitor of histone chaperone ASF1 | 著者 | Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G. | 登録日 | 2023-02-11 | 公開日 | 2023-07-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.564 Å) | 主引用文献 | Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach. Chem.Commun.(Camb.), 59, 2023
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6ERG
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![BU of 6erg by Molmil](/molmil-images/mine/6erg) | Complex of XLF and heterodimer Ku bound to DNA | 分子名称: | DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ... | 著者 | Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B. | 登録日 | 2017-10-18 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining. Nat. Struct. Mol. Biol., 25, 2018
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6ERH
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![BU of 6erh by Molmil](/molmil-images/mine/6erh) | Complex of XLF and heterodimer Ku bound to DNA | 分子名称: | DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ... | 著者 | Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B. | 登録日 | 2017-10-18 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining. Nat. Struct. Mol. Biol., 25, 2018
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6GHD
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![BU of 6ghd by Molmil](/molmil-images/mine/6ghd) | Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases | 分子名称: | 1,2-ETHANEDIOL, Barrier-to-autointegration factor, Emerin, ... | 著者 | Samson, C, Petitalot, A, Celli, F, Herrada, I, Ropars, V, Ledu, M.H, Nhiri, N, Arteni, A.A, Buendia, B, ZinnJustin, S. | 登録日 | 2018-05-07 | 公開日 | 2018-08-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases. Nucleic Acids Res., 46, 2018
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6ERF
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![BU of 6erf by Molmil](/molmil-images/mine/6erf) | Complex of APLF factor and Ku heterodimer bound to DNA | 分子名称: | Aprataxin and PNK-like factor, DNA (34-MER), DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), ... | 著者 | Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B. | 登録日 | 2017-10-18 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining. Nat.Struct.Mol.Biol., 25, 2018
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8A50
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![BU of 8a50 by Molmil](/molmil-images/mine/8a50) | Crystal structure of HSF2BP-ALPHA1 tetramer | 分子名称: | Heat shock factor 2-binding protein, PHOSPHATE ION | 著者 | Miron, S, Legrand, P, Ropars, V, Ghouil, R, Zinn-Justin, S. | 登録日 | 2022-06-13 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.484 Å) | 主引用文献 | BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination. Sci Adv, 9, 2023
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8A51
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![BU of 8a51 by Molmil](/molmil-images/mine/8a51) | Crystal structure of HSF2BP-BRME1 complex | 分子名称: | 1,2-ETHANEDIOL, Break repair meiotic recombinase recruitment factor 1, CHLORIDE ION, ... | 著者 | Miron, S, Legrand, P, Ropars, V, Ghouil, R, Zinn-Justin, S. | 登録日 | 2022-06-13 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination. Sci Adv, 9, 2023
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8ASC
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![BU of 8asc by Molmil](/molmil-images/mine/8asc) | Ku70/80 binds to the Ku-binding motif of PAXX | 分子名称: | DNA (5'-D(P*CP*GP*GP*AP*TP*CP*GP*AP*GP*GP*GP*CP*CP*CP*GP*AP*TP*AP*T)-3'), DNA (5'-D(P*GP*GP*GP*CP*CP*CP*TP*CP*GP*AP*TP*CP*CP*G)-3'), Protein PAXX, ... | 著者 | Seif El Dahan, M, Ropars, V, Charbonnier, J.B. | 登録日 | 2022-08-19 | 公開日 | 2023-06-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
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5KG8
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5I0H
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![BU of 5i0h by Molmil](/molmil-images/mine/5i0h) | Crystal structure of myosin X motor domain in pre-powerstroke state | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Isabet, T, Blanc, F, Sweeney, H.L, Houdusse, A. | 登録日 | 2016-02-04 | 公開日 | 2016-09-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The myosin X motor is optimized for movement on actin bundles. Nat Commun, 7, 2016
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5I0I
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![BU of 5i0i by Molmil](/molmil-images/mine/5i0i) | Crystal structure of myosin X motor domain with 2IQ motifs in pre-powerstroke state | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, Calmodulin, ... | 著者 | Isabet, T, Sweeney, H.L, Houdusse, A. | 登録日 | 2016-02-04 | 公開日 | 2016-09-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | The myosin X motor is optimized for movement on actin bundles. Nat Commun, 7, 2016
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