6GY2
Crystal structure of human Plk1-PBD in complex with WSSSLATPPTLSSpTVLI phosphopeptide from BRCA2
Summary for 6GY2
Entry DOI | 10.2210/pdb6gy2/pdb |
Descriptor | Serine/threonine-protein kinase PLK1, Phosphopeptide of BRCA2, GLYCEROL, ... (4 entities in total) |
Functional Keywords | phosphorylation, chromosomes alignement, dna repair, cell cycle |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 60158.24 |
Authors | Miron, S.,Ropars, V.,Zinn-Justin, S. (deposition date: 2018-06-28, release date: 2019-07-10, Last modification date: 2024-01-17) |
Primary citation | Ehlen, A.,Martin, C.,Miron, S.,Julien, M.,Theillet, F.X.,Ropars, V.,Sessa, G.,Beaurepere, R.,Boucherit, V.,Duchambon, P.,El Marjou, A.,Zinn-Justin, S.,Carreira, A. Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1. Nat Commun, 11:1819-1819, 2020 Cited by PubMed: 32286328DOI: 10.1038/s41467-020-15689-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.11 Å) |
Structure validation
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