6GY2
Crystal structure of human Plk1-PBD in complex with WSSSLATPPTLSSpTVLI phosphopeptide from BRCA2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Serine/threonine-protein kinase PLK1 | polymer | 245 | 28193.1 | 2 | UniProt (P53350) Pfam (PF00659) In PDB | Homo sapiens (Human) | Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13 |
| 2 | C, D | Phosphopeptide of BRCA2 | polymer | 17 | 1840.0 | 2 | UniProt (by SIFTS) (P51587) In PDB | Homo sapiens | |
| 3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | Homo sapiens | ||
| 4 | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
A, B: 365 - 603 (UniProt: P53350)
| PDB | External Database | Details |
|---|---|---|
| Ala 359 | - | expression tag |
| Met 360 | - | expression tag |
| Asp 361 | - | expression tag |
| Pro 362 | - | expression tag |
| Glu 363 | - | expression tag |
| Phe 364 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 60066.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 60158.2 |
