8CJ3
Urea-based foldamer inhibitor c3u_7 chimera in complex with ASF1 histone chaperone
Summary for 8CJ3
| Entry DOI | 10.2210/pdb8cj3/pdb |
| Descriptor | Histone chaperone ASF1A, c3u_7 chimera inhibitor of histone chaperone ASF1 (3 entities in total) |
| Functional Keywords | inhibitor, asf1, histone, protein-protein interaction, chaperone |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 19307.70 |
| Authors | Perrin, M.E.,Li, B.,Mbianda, J.,Ropars, V.,Legrand, P.,Douat, C.,Ochsenbein, F.,Guichard, G. (deposition date: 2023-02-11, release date: 2023-07-05, Last modification date: 2023-11-15) |
| Primary citation | Perrin, M.E.,Li, B.,Mbianda, J.,Bakail, M.,Andre, C.,Moal, G.,Legrand, P.,Ropars, V.,Douat, C.,Ochsenbein, F.,Guichard, G. Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach. Chem.Commun.(Camb.), 59:8696-8699, 2023 Cited by PubMed: 37347155DOI: 10.1039/d3cc01891a PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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