6GHD

Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases

Summary for 6GHD

Entry DOI	10.2210/pdb6ghd/pdb
Descriptor	Emerin, Barrier-to-autointegration factor, Prelamin-A/C, ... (6 entities in total)
Functional Keywords	nuclear envelope, gene expression, ternary complex, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	8
Total formula weight	77150.48
Authors	Samson, C.,Petitalot, A.,Celli, F.,Herrada, I.,Ropars, V.,Ledu, M.H.,Nhiri, N.,Arteni, A.A.,Buendia, B.,ZinnJustin, S. (deposition date: 2018-05-07, release date: 2018-08-08, Last modification date: 2024-01-17)
Primary citation	Samson, C.,Petitalot, A.,Celli, F.,Herrada, I.,Ropars, V.,Le Du, M.H.,Nhiri, N.,Jacquet, E.,Arteni, A.A.,Buendia, B.,Zinn-Justin, S. Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases. Nucleic Acids Res., 46:10460-10473, 2018 Cited by PubMed: 30137533 DOI: 10.1093/nar/gky736 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation