6GHD
Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases
Summary for 6GHD
Entry DOI | 10.2210/pdb6ghd/pdb |
Descriptor | Emerin, Barrier-to-autointegration factor, Prelamin-A/C, ... (6 entities in total) |
Functional Keywords | nuclear envelope, gene expression, ternary complex, protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 77150.48 |
Authors | Samson, C.,Petitalot, A.,Celli, F.,Herrada, I.,Ropars, V.,Ledu, M.H.,Nhiri, N.,Arteni, A.A.,Buendia, B.,ZinnJustin, S. (deposition date: 2018-05-07, release date: 2018-08-08, Last modification date: 2024-01-17) |
Primary citation | Samson, C.,Petitalot, A.,Celli, F.,Herrada, I.,Ropars, V.,Le Du, M.H.,Nhiri, N.,Jacquet, E.,Arteni, A.A.,Buendia, B.,Zinn-Justin, S. Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases. Nucleic Acids Res., 46:10460-10473, 2018 Cited by PubMed: 30137533DOI: 10.1093/nar/gky736 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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