8ASC

Ku70/80 binds to the Ku-binding motif of PAXX

Summary for 8ASC

• Entry DOI: 10.2210/pdb8asc/pdb
• Descriptor: X-ray repair cross-complementing protein 6, X-ray repair cross-complementing protein 5, DNA (5'-D(P*CP*GP*GP*AP*TP*CP*GP*AP*GP*GP*GP*CP*CP*CP*GP*AP*TP*AP*T)-3'), ... (7 entities in total)
• Functional Keywords: nhej, dna repair, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 18
• Total formula weight: 573910.75

Authors

Seif El Dahan, M.,Ropars, V.,Charbonnier, J.B. (deposition date: 2022-08-19, release date: 2023-06-21, Last modification date: 2024-02-07)

• Primary citation: Seif-El-Dahan, M.,Kefala-Stavridi, A.,Frit, P.,Hardwick, S.W.,Chirgadze, D.Y.,Maia De Oliviera, T.,Britton, S.,Barboule, N.,Bossaert, M.,Pandurangan, A.P.,Meek, K.,Blundell, T.L.,Ropars, V.,Calsou, P.,Charbonnier, J.B.,Chaplin, A.K.; PAXX binding to the NHEJ machinery explains functional redundancy with XLF.; Sci Adv, 9:eadg2834-eadg2834, 2023; PubMed: 37256950; DOI: 10.1126/sciadv.adg2834

Experimental method

X-RAY DIFFRACTION (2.95 Å)