8ASC
Ku70/80 binds to the Ku-binding motif of PAXX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, J, N (A, E, K, O) | X-ray repair cross-complementing protein 6 | polymer | 544 | 62629.6 | 4 | UniProt (P12956) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) | Homo sapiens (human) | 5'-deoxyribose-5-phosphate lyase Ku70,5'-dRP lyase Ku70,70 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box-binding factor 75 kDa subunit,CTCBF,DNA repair protein XRCC6,Lupus Ku autoantigen protein p70,Ku70,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 6 |
| 2 | B, F, K, O (B, F, L, P) | X-ray repair cross-complementing protein 5 | polymer | 572 | 65356.8 | 4 | UniProt (P13010) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) | Homo sapiens (human) | 86 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 2,ATP-dependent DNA helicase II 80 kDa subunit,CTC box-binding factor 85 kDa subunit,CTCBF,DNA repair protein XRCC5,Ku80,Ku86,Lupus Ku autoantigen protein p86,Nuclear factor IV,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
| 3 | C, G, L, P (C, G, M, Q) | DNA (5'-D(P*CP*GP*GP*AP*TP*CP*GP*AP*GP*GP*GP*CP*CP*CP*GP*AP*TP*AP*T)-3') | polymer | 30 | 9314.0 | 4 | DNA molecule | ||
| 4 | D, H, M, Q (D, H, N, R) | DNA (5'-D(P*GP*GP*GP*CP*CP*CP*TP*CP*GP*AP*TP*CP*CP*G)-3') | polymer | 15 | 4546.9 | 4 | DNA molecule | ||
| 5 | I, R (J, T) | Protein PAXX | polymer | 28 | 3068.5 | 2 | UniProt (Q9BUH6) | Homo sapiens | Paralog of XRCC4 and XLF,XRCC4-like small protein |
| 6 | S, T, U, V (A, F, K, P) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 7 | AA, BA, CA, W, X... (L, N, O, B, E...) | water | water | 18.0 | 20 | Chemie (HOH) |
Sequence modifications
B, F, L, P: 2 - 555 (UniProt: P13010)
| PDB | External Database | Details |
|---|---|---|
| Met -16 | - | initiating methionine |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| Glu -5 | - | expression tag |
| Asn -4 | - | expression tag |
| Leu -3 | - | expression tag |
| Tyr -2 | - | expression tag |
| Phe -1 | - | expression tag |
| Gln 0 | - | expression tag |
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 573526.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 384.3 | |
| All* | Total formula weight | 573910.7 |
