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8DYV
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BU of 8dyv by Molmil
Structure of human cytoplasmic dynein-1 bound to one Lis1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ...
著者Reimer, J.M, DeSantis, M, Reck-Peterson, S.L, Leschziner, A.E.
登録日2022-08-05
公開日2023-02-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.97 Å)
主引用文献Structures of human dynein in complex with the lissencephaly 1 protein, LIS1.
Elife, 12, 2023
8DYU
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BU of 8dyu by Molmil
Structure of human cytoplasmic dynein-1 bound to two Lis1 proteins
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ...
著者Reimer, J.M, DeSantis, M, Reck-Peterson, S.L, Leschziner, A.E.
登録日2022-08-05
公開日2023-02-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structures of human dynein in complex with the lissencephaly 1 protein, LIS1.
Elife, 12, 2023
3J1T
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BU of 3j1t by Molmil
High affinity dynein microtubule binding domain - tubulin complex
分子名称: Cytoplasmic dynein 1 heavy chain 1, seryl t-RNA synthetase chimera, Tubulin alpha-1B chain, ...
著者Redwine, W.B, Hernandez-Lopez, R, Zou, S, Huang, J, Reck-Peterson, S.L, Leschziner, A.E.
登録日2012-06-25
公開日2012-09-26
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (9.7 Å)
主引用文献Structural basis for microtubule binding and release by dynein.
Science, 337, 2012
5VLJ
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BU of 5vlj by Molmil
Cryo-EM structure of yeast cytoplasmic dynein with Walker B mutation at AAA3 in presence of ATP-VO4
分子名称: Dynein heavy chain, cytoplasmic, Nuclear distribution protein PAC1
著者Cianfrocco, M.A, DeSantis, M.E, Htet, Z.M, Tran, P.T, Reck-Peterson, S.L, Leschziner, A.E.
登録日2017-04-25
公開日2017-09-06
最終更新日2020-01-01
実験手法ELECTRON MICROSCOPY (10.5 Å)
主引用文献Lis1 Has Two Opposing Modes of Regulating Cytoplasmic Dynein.
Cell, 170, 2017
5VH9
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BU of 5vh9 by Molmil
Cryo-EM structure of yeast cytoplasmic dynein-1 with Lis1 and ATP
分子名称: Dynein heavy chain, cytoplasmic, Nuclear distribution protein PAC1
著者Cianfrocco, M.A, DeSantis, M.E, Htet, Z.M, Tran, P.T, Reck-Peterson, S.L, Leschziner, A.E.
登録日2017-04-12
公開日2017-09-06
最終更新日2020-01-01
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Lis1 Has Two Opposing Modes of Regulating Cytoplasmic Dynein.
Cell, 170, 2017
3J1U
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BU of 3j1u by Molmil
Low affinity dynein microtubule binding domain - tubulin complex
分子名称: Cytoplasmic dynein 1 heavy chain 1, seryl t-RNA synthetase chimera, Tubulin alpha-1B chain, ...
著者Redwine, W.B, Hernandez-Lopez, R, Zou, S, Huang, J, Reck-Peterson, S.L, Leschziner, A.E.
登録日2012-06-25
公開日2012-09-26
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (9.7 Å)
主引用文献Structural basis for microtubule binding and release by dynein.
Science, 337, 2012
7MGM
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BU of 7mgm by Molmil
Structure of yeast cytoplasmic dynein with AAA3 Walker B mutation bound to Lis1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Lahiri, I, Reimer, J.M, Leschziner, A.E.
登録日2021-04-12
公開日2022-01-19
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for cytoplasmic dynein-1 regulation by Lis1.
Elife, 11, 2022
7THZ
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BU of 7thz by Molmil
Structure of Leucine Rich Repeat Kinase 2's ROC domain interacting with the microtubule facing the plus end
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2
著者Matyszewski, M, Leschziner, A.E.
登録日2022-01-12
公開日2022-12-28
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules.
Nat.Struct.Mol.Biol., 29, 2022
7THY
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BU of 7thy by Molmil
Structure of Leucine Rich Repeat Kinase 2's ROC domain interacting with the microtubule facing the minus end
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2
著者Matyszewski, M, Leschziner, A.E.
登録日2022-01-12
公開日2022-12-28
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules.
Nat.Struct.Mol.Biol., 29, 2022
6VNO
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BU of 6vno by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
著者Leschziner, A, Deniston, C, Lahiri, I.
登録日2020-01-29
公開日2020-08-26
最終更新日2020-12-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP8
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BU of 6vp8 by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
分子名称: Leucine-rich repeat serine/threonine-protein kinase 2
著者Leschziner, A, Deniston, C, Lahiri, I.
登録日2020-02-01
公開日2020-08-26
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP6
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BU of 6vp6 by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
著者Leschziner, A, Deniston, C, Lahiri, I.
登録日2020-02-01
公開日2020-08-26
最終更新日2020-12-23
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP7
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BU of 6vp7 by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
分子名称: Leucine-rich repeat serine/threonine-protein kinase 2
著者Leschziner, A, Deniston, C, Lahiri, I.
登録日2020-02-01
公開日2020-08-26
最終更新日2020-12-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
8DZZ
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BU of 8dzz by Molmil
Cryo-EM structure of chi dynein bound to Lis1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
著者Reimer, J.M, Lahiri, I, Leschziner, A.E.
登録日2022-08-08
公開日2023-08-30
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge.
Nat.Struct.Mol.Biol., 30, 2023
8E06
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BU of 8e06 by Molmil
Symmetry expansion of dimeric LRRK1
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 1
著者Reimer, J.M, Lin, Y.X, Leschziner, A.E.
登録日2022-08-08
公開日2023-08-30
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure of LRRK1 and mechanisms of autoinhibition and activation.
Nat.Struct.Mol.Biol., 30, 2023
8E04
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BU of 8e04 by Molmil
Structure of monomeric LRRK1
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 1
著者Reimer, J.M, Mathea, S, Chatterjee, D, Knapp, S, Leschziner, A.E.
登録日2022-08-08
公開日2023-08-30
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of LRRK1 and mechanisms of autoinhibition and activation.
Nat.Struct.Mol.Biol., 30, 2023
8E00
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BU of 8e00 by Molmil
Symmetry expansion of yeast cytoplasmic dynein-1 bound to Lis1 in the chi conformation.
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
著者Reimer, J.M, Lahiri, I, Leschziner, A.E.
登録日2022-08-08
公開日2023-08-30
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge.
Nat.Struct.Mol.Biol., 30, 2023
8E05
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BU of 8e05 by Molmil
Structure of dimeric LRRK1
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 1
著者Reimer, J.M, Lin, Y.X, Leschziner, A.E.
登録日2022-08-08
公開日2023-08-30
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structure of LRRK1 and mechanisms of autoinhibition and activation.
Nat.Struct.Mol.Biol., 30, 2023

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件を2024-06-26に公開中

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