8DYV
| Structure of human cytoplasmic dynein-1 bound to one Lis1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | 著者 | Reimer, J.M, DeSantis, M, Reck-Peterson, S.L, Leschziner, A.E. | 登録日 | 2022-08-05 | 公開日 | 2023-02-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | 主引用文献 | Structures of human dynein in complex with the lissencephaly 1 protein, LIS1. Elife, 12, 2023
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8DYU
| Structure of human cytoplasmic dynein-1 bound to two Lis1 proteins | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | 著者 | Reimer, J.M, DeSantis, M, Reck-Peterson, S.L, Leschziner, A.E. | 登録日 | 2022-08-05 | 公開日 | 2023-02-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of human dynein in complex with the lissencephaly 1 protein, LIS1. Elife, 12, 2023
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3J1T
| High affinity dynein microtubule binding domain - tubulin complex | 分子名称: | Cytoplasmic dynein 1 heavy chain 1, seryl t-RNA synthetase chimera, Tubulin alpha-1B chain, ... | 著者 | Redwine, W.B, Hernandez-Lopez, R, Zou, S, Huang, J, Reck-Peterson, S.L, Leschziner, A.E. | 登録日 | 2012-06-25 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (9.7 Å) | 主引用文献 | Structural basis for microtubule binding and release by dynein. Science, 337, 2012
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5VLJ
| Cryo-EM structure of yeast cytoplasmic dynein with Walker B mutation at AAA3 in presence of ATP-VO4 | 分子名称: | Dynein heavy chain, cytoplasmic, Nuclear distribution protein PAC1 | 著者 | Cianfrocco, M.A, DeSantis, M.E, Htet, Z.M, Tran, P.T, Reck-Peterson, S.L, Leschziner, A.E. | 登録日 | 2017-04-25 | 公開日 | 2017-09-06 | 最終更新日 | 2020-01-01 | 実験手法 | ELECTRON MICROSCOPY (10.5 Å) | 主引用文献 | Lis1 Has Two Opposing Modes of Regulating Cytoplasmic Dynein. Cell, 170, 2017
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5VH9
| Cryo-EM structure of yeast cytoplasmic dynein-1 with Lis1 and ATP | 分子名称: | Dynein heavy chain, cytoplasmic, Nuclear distribution protein PAC1 | 著者 | Cianfrocco, M.A, DeSantis, M.E, Htet, Z.M, Tran, P.T, Reck-Peterson, S.L, Leschziner, A.E. | 登録日 | 2017-04-12 | 公開日 | 2017-09-06 | 最終更新日 | 2020-01-01 | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | 主引用文献 | Lis1 Has Two Opposing Modes of Regulating Cytoplasmic Dynein. Cell, 170, 2017
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3J1U
| Low affinity dynein microtubule binding domain - tubulin complex | 分子名称: | Cytoplasmic dynein 1 heavy chain 1, seryl t-RNA synthetase chimera, Tubulin alpha-1B chain, ... | 著者 | Redwine, W.B, Hernandez-Lopez, R, Zou, S, Huang, J, Reck-Peterson, S.L, Leschziner, A.E. | 登録日 | 2012-06-25 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (9.7 Å) | 主引用文献 | Structural basis for microtubule binding and release by dynein. Science, 337, 2012
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7MGM
| Structure of yeast cytoplasmic dynein with AAA3 Walker B mutation bound to Lis1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Lahiri, I, Reimer, J.M, Leschziner, A.E. | 登録日 | 2021-04-12 | 公開日 | 2022-01-19 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for cytoplasmic dynein-1 regulation by Lis1. Elife, 11, 2022
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7THZ
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7THY
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6VNO
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6VP8
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6VP6
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6VP7
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8DZZ
| Cryo-EM structure of chi dynein bound to Lis1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ... | 著者 | Reimer, J.M, Lahiri, I, Leschziner, A.E. | 登録日 | 2022-08-08 | 公開日 | 2023-08-30 | 最終更新日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge. Nat.Struct.Mol.Biol., 30, 2023
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8E06
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8E04
| Structure of monomeric LRRK1 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 1 | 著者 | Reimer, J.M, Mathea, S, Chatterjee, D, Knapp, S, Leschziner, A.E. | 登録日 | 2022-08-08 | 公開日 | 2023-08-30 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of LRRK1 and mechanisms of autoinhibition and activation. Nat.Struct.Mol.Biol., 30, 2023
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8E00
| Symmetry expansion of yeast cytoplasmic dynein-1 bound to Lis1 in the chi conformation. | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ... | 著者 | Reimer, J.M, Lahiri, I, Leschziner, A.E. | 登録日 | 2022-08-08 | 公開日 | 2023-08-30 | 最終更新日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge. Nat.Struct.Mol.Biol., 30, 2023
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8E05
| Structure of dimeric LRRK1 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 1 | 著者 | Reimer, J.M, Lin, Y.X, Leschziner, A.E. | 登録日 | 2022-08-08 | 公開日 | 2023-08-30 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structure of LRRK1 and mechanisms of autoinhibition and activation. Nat.Struct.Mol.Biol., 30, 2023
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