5VH9

Cryo-EM structure of yeast cytoplasmic dynein-1 with Lis1 and ATP

Summary for 5VH9

• Entry DOI: 10.2210/pdb5vh9/pdb
• Related: 5VLJ
• EMDB information: 8673 8706
• Descriptor: Dynein heavy chain, cytoplasmic, Nuclear distribution protein PAC1 (2 entities in total)
• Functional Keywords: cytoplasmic dynein, lis1, motor protein
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Total number of polymer chains: 2
• Total formula weight: 313311.70

Authors

Cianfrocco, M.A.,DeSantis, M.E.,Htet, Z.M.,Tran, P.T.,Reck-Peterson, S.L.,Leschziner, A.E. (deposition date: 2017-04-12, release date: 2017-09-06, Last modification date: 2020-01-01)

• Primary citation: DeSantis, M.E.,Cianfrocco, M.A.,Htet, Z.M.,Tran, P.T.,Reck-Peterson, S.L.,Leschziner, A.E.; Lis1 Has Two Opposing Modes of Regulating Cytoplasmic Dynein.; Cell, 170:1197-1208.e12, 2017; PubMed: 28886386; DOI: 10.1016/j.cell.2017.08.037

Experimental method

ELECTRON MICROSCOPY (7.7 Å)