8DYU

Structure of human cytoplasmic dynein-1 bound to two Lis1 proteins

Summary for 8DYU

• Entry DOI: 10.2210/pdb8dyu/pdb
• Related: 8DYV
• EMDB information: 27782 27783
• Descriptor: Cytoplasmic dynein 1 heavy chain 1, Platelet-activating factor acetylhydrolase IB subunit beta, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: dynein, motor protein, transport
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 476188.21

Authors

Reimer, J.M.,DeSantis, M.,Reck-Peterson, S.L.,Leschziner, A.E. (deposition date: 2022-08-05, release date: 2023-02-01, Last modification date: 2024-06-12)

• Primary citation: Reimer, J.M.,DeSantis, M.E.,Reck-Peterson, S.L.,Leschziner, A.E.; Structures of human dynein in complex with the lissencephaly 1 protein, LIS1.; Elife, 12:-, 2023; PubMed: 36692009; DOI: 10.7554/eLife.84302

Experimental method

ELECTRON MICROSCOPY (4 Å)