8DZZ

Cryo-EM structure of chi dynein bound to Lis1

Summary for 8DZZ

Entry DOI	10.2210/pdb8dzz/pdb
Related	7MGM 8E00
EMDB information	27810 27811
Descriptor	Dynein heavy chain, cytoplasmic, Nuclear distribution protein PAC1, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywords	motor protein, dynein
Biological source	Saccharomyces cerevisiae (baker's yeast) More
Total number of polymer chains	6
Total formula weight	895067.96
Authors	Reimer, J.M.,Lahiri, I.,Leschziner, A.E. (deposition date: 2022-08-08, release date: 2023-08-30, Last modification date: 2023-09-27)
Primary citation	Karasmanis, E.P.,Reimer, J.M.,Kendrick, A.A.,Nguyen, K.H.V.,Rodriguez, J.A.,Truong, J.B.,Lahiri, I.,Reck-Peterson, S.L.,Leschziner, A.E. Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge. Nat.Struct.Mol.Biol., 30:1357-1364, 2023 Cited by PubMed: 37620585 DOI: 10.1038/s41594-023-01069-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.1 Å)

Structure validation