8DZZ

Cryo-EM structure of chi dynein bound to Lis1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0007018	biological_process	microtubule-based movement
A	0008569	molecular_function	minus-end-directed microtubule motor activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0030286	cellular_component	dynein complex
A	0045505	molecular_function	dynein intermediate chain binding
A	0051959	molecular_function	dynein light intermediate chain binding
B	0000132	biological_process	establishment of mitotic spindle orientation
B	0000776	cellular_component	kinetochore
B	0000922	cellular_component	spindle pole
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005635	cellular_component	nuclear envelope
B	0005737	cellular_component	cytoplasm
B	0005856	cellular_component	cytoskeleton
B	0005874	cellular_component	microtubule
B	0005875	cellular_component	microtubule associated complex
B	0005881	cellular_component	cytoplasmic microtubule
B	0007097	biological_process	nuclear migration
B	0030473	biological_process	nuclear migration along microtubule
B	0031023	biological_process	microtubule organizing center organization
B	0042802	molecular_function	identical protein binding
B	0047496	biological_process	vesicle transport along microtubule
B	0051010	molecular_function	microtubule plus-end binding
B	0051012	biological_process	microtubule sliding
B	0051301	biological_process	cell division
B	0070840	molecular_function	dynein complex binding
C	0000132	biological_process	establishment of mitotic spindle orientation
C	0000776	cellular_component	kinetochore
C	0000922	cellular_component	spindle pole
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005635	cellular_component	nuclear envelope
C	0005737	cellular_component	cytoplasm
C	0005856	cellular_component	cytoskeleton
C	0005874	cellular_component	microtubule
C	0005875	cellular_component	microtubule associated complex
C	0005881	cellular_component	cytoplasmic microtubule
C	0007097	biological_process	nuclear migration
C	0030473	biological_process	nuclear migration along microtubule
C	0031023	biological_process	microtubule organizing center organization
C	0042802	molecular_function	identical protein binding
C	0047496	biological_process	vesicle transport along microtubule
C	0051010	molecular_function	microtubule plus-end binding
C	0051012	biological_process	microtubule sliding
C	0051301	biological_process	cell division
C	0070840	molecular_function	dynein complex binding
D	0005524	molecular_function	ATP binding
D	0007018	biological_process	microtubule-based movement
D	0008569	molecular_function	minus-end-directed microtubule motor activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0030286	cellular_component	dynein complex
D	0045505	molecular_function	dynein intermediate chain binding
D	0051959	molecular_function	dynein light intermediate chain binding
E	0000132	biological_process	establishment of mitotic spindle orientation
E	0000776	cellular_component	kinetochore
E	0000922	cellular_component	spindle pole
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005635	cellular_component	nuclear envelope
E	0005737	cellular_component	cytoplasm
E	0005856	cellular_component	cytoskeleton
E	0005874	cellular_component	microtubule
E	0005875	cellular_component	microtubule associated complex
E	0005881	cellular_component	cytoplasmic microtubule
E	0007097	biological_process	nuclear migration
E	0030473	biological_process	nuclear migration along microtubule
E	0031023	biological_process	microtubule organizing center organization
E	0042802	molecular_function	identical protein binding
E	0047496	biological_process	vesicle transport along microtubule
E	0051010	molecular_function	microtubule plus-end binding
E	0051012	biological_process	microtubule sliding
E	0051301	biological_process	cell division
E	0070840	molecular_function	dynein complex binding
F	0000132	biological_process	establishment of mitotic spindle orientation
F	0000776	cellular_component	kinetochore
F	0000922	cellular_component	spindle pole
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005635	cellular_component	nuclear envelope
F	0005737	cellular_component	cytoplasm
F	0005856	cellular_component	cytoskeleton
F	0005874	cellular_component	microtubule
F	0005875	cellular_component	microtubule associated complex
F	0005881	cellular_component	cytoplasmic microtubule
F	0007097	biological_process	nuclear migration
F	0030473	biological_process	nuclear migration along microtubule
F	0031023	biological_process	microtubule organizing center organization
F	0042802	molecular_function	identical protein binding
F	0047496	biological_process	vesicle transport along microtubule
F	0051010	molecular_function	microtubule plus-end binding
F	0051012	biological_process	microtubule sliding
F	0051301	biological_process	cell division
F	0070840	molecular_function	dynein complex binding

Functional Information from PROSITE/UniProt

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. IASCsrDqTVKIWDF

Chain	Residue	Details
B	ILE270-PHE284
B	CYS373-ILE387

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	GLY1796
A	GLY2074
A	GLY2418
A	GLY2760
D	GLY1796
D	GLY2074
D	GLY2418
D	GLY2760

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