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8DZZ

Cryo-EM structure of chi dynein bound to Lis1

Functional Information from GO Data
ChainGOidnamespacecontents
A0005524molecular_functionATP binding
A0007018biological_processmicrotubule-based movement
A0008569molecular_functionminus-end-directed microtubule motor activity
A0030286cellular_componentdynein complex
A0045505molecular_functiondynein intermediate chain binding
A0051959molecular_functiondynein light intermediate chain binding
B0000132biological_processestablishment of mitotic spindle orientation
B0000776cellular_componentkinetochore
B0000922cellular_componentspindle pole
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005635cellular_componentnuclear envelope
B0005737cellular_componentcytoplasm
B0005856cellular_componentcytoskeleton
B0005874cellular_componentmicrotubule
B0005875cellular_componentmicrotubule associated complex
B0005881cellular_componentcytoplasmic microtubule
B0007017biological_processmicrotubule-based process
B0007097biological_processnuclear migration
B0030473biological_processnuclear migration along microtubule
B0031023biological_processmicrotubule organizing center organization
B0042802molecular_functionidentical protein binding
B0047496biological_processvesicle transport along microtubule
B0051010molecular_functionmicrotubule plus-end binding
B0051012biological_processmicrotubule sliding
B0051301biological_processcell division
B0070840molecular_functiondynein complex binding
C0000132biological_processestablishment of mitotic spindle orientation
C0000776cellular_componentkinetochore
C0000922cellular_componentspindle pole
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005635cellular_componentnuclear envelope
C0005737cellular_componentcytoplasm
C0005856cellular_componentcytoskeleton
C0005874cellular_componentmicrotubule
C0005875cellular_componentmicrotubule associated complex
C0005881cellular_componentcytoplasmic microtubule
C0007017biological_processmicrotubule-based process
C0007097biological_processnuclear migration
C0030473biological_processnuclear migration along microtubule
C0031023biological_processmicrotubule organizing center organization
C0042802molecular_functionidentical protein binding
C0047496biological_processvesicle transport along microtubule
C0051010molecular_functionmicrotubule plus-end binding
C0051012biological_processmicrotubule sliding
C0051301biological_processcell division
C0070840molecular_functiondynein complex binding
D0005524molecular_functionATP binding
D0007018biological_processmicrotubule-based movement
D0008569molecular_functionminus-end-directed microtubule motor activity
D0030286cellular_componentdynein complex
D0045505molecular_functiondynein intermediate chain binding
D0051959molecular_functiondynein light intermediate chain binding
E0000132biological_processestablishment of mitotic spindle orientation
E0000776cellular_componentkinetochore
E0000922cellular_componentspindle pole
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005635cellular_componentnuclear envelope
E0005737cellular_componentcytoplasm
E0005856cellular_componentcytoskeleton
E0005874cellular_componentmicrotubule
E0005875cellular_componentmicrotubule associated complex
E0005881cellular_componentcytoplasmic microtubule
E0007017biological_processmicrotubule-based process
E0007097biological_processnuclear migration
E0030473biological_processnuclear migration along microtubule
E0031023biological_processmicrotubule organizing center organization
E0042802molecular_functionidentical protein binding
E0047496biological_processvesicle transport along microtubule
E0051010molecular_functionmicrotubule plus-end binding
E0051012biological_processmicrotubule sliding
E0051301biological_processcell division
E0070840molecular_functiondynein complex binding
F0000132biological_processestablishment of mitotic spindle orientation
F0000776cellular_componentkinetochore
F0000922cellular_componentspindle pole
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005635cellular_componentnuclear envelope
F0005737cellular_componentcytoplasm
F0005856cellular_componentcytoskeleton
F0005874cellular_componentmicrotubule
F0005875cellular_componentmicrotubule associated complex
F0005881cellular_componentcytoplasmic microtubule
F0007017biological_processmicrotubule-based process
F0007097biological_processnuclear migration
F0030473biological_processnuclear migration along microtubule
F0031023biological_processmicrotubule organizing center organization
F0042802molecular_functionidentical protein binding
F0047496biological_processvesicle transport along microtubule
F0051010molecular_functionmicrotubule plus-end binding
F0051012biological_processmicrotubule sliding
F0051301biological_processcell division
F0070840molecular_functiondynein complex binding
Functional Information from PROSITE/UniProt
site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. IASCsrDqTVKIWDF
ChainResidueDetails
BILE270-PHE284
BCYS373-ILE387

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues442
DetailsRegion: {"description":"AAA 1","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues524
DetailsRegion: {"description":"AAA 4","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues458
DetailsRegion: {"description":"AAA 5","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues200
DetailsCoiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues56
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues156
DetailsRepeat: {"description":"WD 1"}
ChainResidueDetails

site_idSWS_FT_FI7
Number of Residues164
DetailsRepeat: {"description":"WD 3"}
ChainResidueDetails

site_idSWS_FT_FI8
Number of Residues156
DetailsRepeat: {"description":"WD 4"}
ChainResidueDetails

site_idSWS_FT_FI9
Number of Residues156
DetailsRepeat: {"description":"WD 6"}
ChainResidueDetails

site_idSWS_FT_FI10
Number of Residues140
DetailsRepeat: {"description":"WD 7"}
ChainResidueDetails

site_idSWS_FT_FI11
Number of Residues96
DetailsRepeat: {"description":"WD 2"}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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