5OXE
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2X6V
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![BU of 2x6v by Molmil](/molmil-images/mine/2x6v) | Crystal structure of human TBX5 in the DNA-bound and DNA-free form | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 5'-D(*TP*AP*AP*GP*GP*TP*GP*TP*GP*AP*GP)-3', 5'-D(*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP)-3', ... | 著者 | Ptchelkine, D, Stirnimann, C.U, Grimm, C, Mueller, C.W. | 登録日 | 2010-02-22 | 公開日 | 2010-04-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Basis of Tbx5-DNA Recognition: The T-Box Domain in its DNA-Bound and -Unbound Form. J.Mol.Biol., 400, 2010
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5N88
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![BU of 5n88 by Molmil](/molmil-images/mine/5n88) | Crystal structure of antibody bound to viral protein | 分子名称: | PC4 and SFRS1-interacting protein, VH59 antibody | 著者 | Bao, L, Hannon, C, Cruz-Migoni, A, Ptchelkine, D, Sun, M.-y, Derveni, M, Bunjobpol, W, Chambers, J.S, Simmons, A, Phillips, S.E.V, Rabbitts, T.H. | 登録日 | 2017-02-23 | 公開日 | 2017-12-20 | 最終更新日 | 2019-10-16 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein. Sci Rep, 7, 2017
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6QJS
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![BU of 6qjs by Molmil](/molmil-images/mine/6qjs) | Crystal structure of a DNA dodecamer containing a tetramethylpiperidinoxyl (nitroxide) spin label | 分子名称: | COBALT HEXAMMINE(III), DNA (5'-D(P*GP*CP*AP*AP*AP*TP*TP*(S6M)P*GP*CP*G)-3') | 著者 | Hardwick, J.S, Haugland, M.M, Ptchelkine, D, Brown, T, Anderson, E.E. | 登録日 | 2019-01-24 | 公開日 | 2020-02-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | 2'-Alkynyl spin-labelling is a minimally perturbing tool for DNA structural analysis. Nucleic Acids Res., 48, 2020
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6QJR
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![BU of 6qjr by Molmil](/molmil-images/mine/6qjr) | Crystal structure of a DNA dodecamer containing a tetramethylpyrrolinoxyl (nitroxide) spin label | 分子名称: | DNA (5'-D(*CP*GP*CP*AP*AP*AP*AP*AP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*TP*TP*TP*TP*(5NO)P*GP*CP*G)-3') | 著者 | Hardwick, J.S, Haugland, M.M, Ptchelkine, D, Brown, T, Anderson, E.E. | 登録日 | 2019-01-24 | 公開日 | 2020-02-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | 2'-Alkynyl spin-labelling is a minimally perturbing tool for DNA structural analysis. Nucleic Acids Res., 48, 2020
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8ORS
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![BU of 8ors by Molmil](/molmil-images/mine/8ors) | Knockout of GMC-oxidoreductase genes reveals that functional redundancy preserves mimivirus essential functions | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Putative GMC-type oxidoreductase | 著者 | Alempic, J.M, Bisio, H, Villalta, A, Santini, S, Lartigue, A, Schmitt, A, Bugnot, C, Notaro, A, Belmudes, L, Adrait, A, Poirot, O, Ptchelkine, D, De Castro, C, Coute, Y, Abergel, C. | 登録日 | 2023-04-17 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Functional redundancy revealed by the deletion of the mimivirus GMC-oxidoreductase genes. Microlife, 5, 2024
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8ORH
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![BU of 8orh by Molmil](/molmil-images/mine/8orh) | Knockout of GMC-oxidoreductase genes reveals that functional redundancy preserves mimivirus essential functions | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Putative GMC-type oxidoreductase | 著者 | Alempic, J.M, Bisio, H, Villalta, A, Santini, S, Lartigue, A, Schmitt, A, Bugnot, C, Notaro, A, Belmudes, L, Adrait, A, Poirot, O, Ptchelkine, D, De Castro, C, Coute, Y, Abergel, C. | 登録日 | 2023-04-14 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Functional redundancy revealed by the deletion of the mimivirus GMC-oxidoreductase genes. Microlife, 5, 2024
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4ELC
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![BU of 4elc by Molmil](/molmil-images/mine/4elc) | Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A C134 mutant with MTSEA modified Cys-165 | 分子名称: | (2S)-2-hydroxybutanedioic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, Botulinum neurotoxin A light chain, ... | 著者 | Stura, E.A, Vera, L, Ptchelkine, D, Bakirci, H, Garcia, S, Dive, V. | 登録日 | 2012-04-10 | 公開日 | 2012-08-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Framework for Covalent Inhibition of Clostridium botulinum Neurotoxin A by Targeting Cys165. J.Biol.Chem., 287, 2012
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8PK7
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![BU of 8pk7 by Molmil](/molmil-images/mine/8pk7) | Helical reconstruction of CHIKV nsP3 helical scaffolds | 分子名称: | Non-structural protein 3, ZINC ION | 著者 | Reguera, J, Hons, M, Zimberger, C, Ptchelkine, D, Jones, R, Desfosses, A. | 登録日 | 2023-06-25 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | 主引用文献 | The alphavirus nsP3 protein forms helical tubular scaffolds important for viral replication and particle assembly To Be Published
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8PHZ
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![BU of 8phz by Molmil](/molmil-images/mine/8phz) | Helical reconstruction of CHIKV nsP3 helical scaffolds | 分子名称: | Non-structural protein 3, ZINC ION | 著者 | Reguera, J, Hons, M, Zimberger, C, Ptchelkine, D, Jones, R, Desfosses, A. | 登録日 | 2023-06-20 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (2.35 Å) | 主引用文献 | The alphavirus nsP3 protein forms helical tubular scaffolds important for viral replication and particle assembly To be published
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4EL4
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![BU of 4el4 by Molmil](/molmil-images/mine/4el4) | Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A C134S/C165S double mutant | 分子名称: | 1,2-ETHANEDIOL, Botulinum neurotoxin A light chain, GLYCEROL, ... | 著者 | Stura, E.A, Vera, L, Ptchelkine, D, Dive, V. | 登録日 | 2012-04-10 | 公開日 | 2012-08-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structural Framework for Covalent Inhibition of Clostridium botulinum Neurotoxin A by Targeting Cys165. J.Biol.Chem., 287, 2012
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2VY2
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![BU of 2vy2 by Molmil](/molmil-images/mine/2vy2) | Structure of LEAFY transcription factor from Arabidopsis thaliana in complex with DNA from AG-I promoter | 分子名称: | 5'-D(*AP*TP*TP*TP*AP*AP*TP*CP*CP*AP *AP*TP*GP*GP*TP*TP*AP*CP*AP*A)-3', PROTEIN LEAFY | 著者 | Hames, C, Ptchelkine, D, Grimm, C, Thevenon, E, Moyroud, E, Gerard, F, Martiel, J.L, Benlloch, R, Parcy, F, Muller, C.W. | 登録日 | 2008-07-16 | 公開日 | 2008-09-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis for Leafy Floral Switch Function and Similarity with Helix-Turn-Helix Proteins. Embo J., 27, 2008
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2VY1
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![BU of 2vy1 by Molmil](/molmil-images/mine/2vy1) | Structure of LEAFY transcription factor from Arabidopsis thaliana in complex with DNA from AP1 promoter | 分子名称: | 5'-D(*TP*TP*AP*CP*GP*GP*AP*CP*CP*AP *CP*TP*GP*GP*TP*CP*CP*TP*TP*CP)-3', PROTEIN LEAFY | 著者 | Hames, C, Ptchelkine, D, Grimm, C, Thevenon, E, Moyroud, E, Gerard, F, Martiel, J.L, Benlloch, R, Parcy, F, Muller, C.W. | 登録日 | 2008-07-16 | 公開日 | 2008-09-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | 主引用文献 | Structural Basis for Leafy Floral Switch Function and Similarity with Helix-Turn-Helix Proteins. Embo J., 27, 2008
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5MVT
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![BU of 5mvt by Molmil](/molmil-images/mine/5mvt) | Crystal structure of an A-DNA dodecamer featuring an alternating pyrimidine-purine sequence | 分子名称: | COBALT (III) ION, DNA | 著者 | Hardwick, J.S, Ptchelkine, D, Phillips, S.E.V, Brown, T. | 登録日 | 2017-01-17 | 公開日 | 2017-05-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.896 Å) | 主引用文献 | 5-Formylcytosine does not change the global structure of DNA. Nat. Struct. Mol. Biol., 24, 2017
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5MVL
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![BU of 5mvl by Molmil](/molmil-images/mine/5mvl) | Crystal structure of an A-DNA dodecamer containing 5-bromouracil | 分子名称: | Brominated DNA dodecamer, MAGNESIUM ION | 著者 | Hardwick, J.S, Ptchelkine, D, Phillips, S.E.V, Brown, T. | 登録日 | 2017-01-16 | 公開日 | 2017-05-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.405 Å) | 主引用文献 | 5-Formylcytosine does not change the global structure of DNA. Nat. Struct. Mol. Biol., 24, 2017
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5MVQ
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![BU of 5mvq by Molmil](/molmil-images/mine/5mvq) | Crystal structure of an unmodified, self-complementary dodecamer. | 分子名称: | DNA, MAGNESIUM ION | 著者 | Hardwick, J.S, Ptchelkine, D, Phillips, S.E.V, Brown, T. | 登録日 | 2017-01-17 | 公開日 | 2017-05-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.604 Å) | 主引用文献 | 5-Formylcytosine does not change the global structure of DNA. Nat. Struct. Mol. Biol., 24, 2017
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5MVU
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5MVP
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![BU of 5mvp by Molmil](/molmil-images/mine/5mvp) | Crystal structure of an A-DNA dodecamer containing the GGGCCC motif | 分子名称: | DNA, POTASSIUM ION | 著者 | Hardwick, J.S, Ptchelkine, D, Phillips, S.E.V, Brown, T. | 登録日 | 2017-01-17 | 公開日 | 2017-05-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.606 Å) | 主引用文献 | 5-Formylcytosine does not change the global structure of DNA. Nat. Struct. Mol. Biol., 24, 2017
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5MVK
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4KUF
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![BU of 4kuf by Molmil](/molmil-images/mine/4kuf) | Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A C134 mutant with MTSEA modified Cys-165 causing stretch disorder | 分子名称: | (2S)-2-hydroxybutanedioic acid, 1,2-ETHANEDIOL, Botulinum neurotoxin A light chain, ... | 著者 | Stura, E.A, Vera, L, Ptchelkine, D, Bakirci, H, Garcia, S, Dive, V. | 登録日 | 2013-05-22 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.697 Å) | 主引用文献 | Covalent modification of the active site cysteine stresses Clostridium botulinum neurotoxin A To be Published
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4EJ5
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![BU of 4ej5 by Molmil](/molmil-images/mine/4ej5) | Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A wild-type | 分子名称: | 1,2-ETHANEDIOL, Botulinum neurotoxin A light chain, CARBONATE ION, ... | 著者 | Stura, E.A, Vera, L, Dive, V. | 登録日 | 2012-04-06 | 公開日 | 2012-08-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structural Framework for Covalent Inhibition of Clostridium botulinum Neurotoxin A by Targeting Cys165. J.Biol.Chem., 287, 2012
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2X6U
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![BU of 2x6u by Molmil](/molmil-images/mine/2x6u) | Crystal structure of human TBX5 in the DNA-free form | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, MAGNESIUM ION, T-BOX TRANSCRIPTION FACTOR TBX5 | 著者 | Stirnimann, C.U, Mueller, C.W. | 登録日 | 2010-02-22 | 公開日 | 2010-04-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis of Tbx5-DNA Recognition: The T-Box Domain in its DNA-Bound and -Unbound Form. J.Mol.Biol., 400, 2010
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4KTX
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![BU of 4ktx by Molmil](/molmil-images/mine/4ktx) | Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A C134S mutant with covalent inhibitor that modifies Cys-165 causing disorder in 167-174 stretch | 分子名称: | Botulinum neurotoxin A light chain, GLYCEROL, Peptide inhibitor MPT-DPP-ARG-G-LEU-NH2, ... | 著者 | Stura, E.A, Vera, L, Guitot, K, Dive, V. | 登録日 | 2013-05-21 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Covalent modification of the active site cysteine stresses Clostridium botulinum neurotoxin A To be Published
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4KS6
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![BU of 4ks6 by Molmil](/molmil-images/mine/4ks6) | Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A C134S mutant with covalent inhibitor that modifies Cys-165 causing disorder in 166-174 stretch | 分子名称: | 1,2-ETHANEDIOL, Botulinum neurotoxin A light chain, DI(HYDROXYETHYL)ETHER, ... | 著者 | Stura, E.A, Vera, L, Guitot, K, Dive, V. | 登録日 | 2013-05-17 | 公開日 | 2014-06-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Covalent modification of the active site cysteine stresses Clostridium botulinum neurotoxin A To be Published
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