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Structure of NS2B-NS3 Protease from Zika Virus caught after self-cleavage
分子名称:	CHLORIDE ION, Serine protease NS3, Serine protease subunit NS2B
著者	Phoo, W.W, Li, Y.
登録日	2016-06-27
公開日	2016-10-26
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (1.839 Å)
主引用文献	Structure of the NS2B-NS3 protease from Zika virus after self-cleavage. Nat Commun, 7, 2016

5YVV

Crystal structure of full length NS3 protein (gD4NS2BNS3) from DENV4 in closed conformation
分子名称:	Genome polyprotein
著者	PHOO, W.W, Sahili, A.E.
登録日	2017-11-27
公開日	2018-12-05
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (3.097 Å)
主引用文献	Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain To Be Published

5YVJ

Crystal structure of full length NS2B47-NS3 (gD4NS2BNS3) from Dengue virus 4 in open conformation
分子名称:	GLYCEROL, Genome polyprotein
著者	Phoo, W.W, El Sahili, A.
登録日	2017-11-26
公開日	2018-11-28
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.508 Å)
主引用文献	Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain To Be Published

5YVW

Crystal structure of full length NS3 protein (eD4NS2BNS3) from DENV4 in closed conformation
分子名称:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Genome polyprotein
著者	PHOO, W.W, El Sahili, A.
登録日	2017-11-27
公開日	2018-12-05
最終更新日	2024-03-27
実験手法	X-RAY DIFFRACTION (3.1 Å)
主引用文献	Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain To Be Published

5ZOB

Crystal structure of Zika NS3 protease with 4-guanidinomethyl-phenylacetyl-Arg-Arg-Arg-4-amidinobenzylamide
分子名称:	4-guanidinomethyl-phenylacetyl-Arg-Arg-Arg-4-amidinobenzylamide, NS3 protease, Serine protease subunit NS2B
著者	Phoo, W.W, Wirawan, M.
登録日	2018-04-12
公開日	2018-10-17
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors. Antiviral Res., 160, 2018

5ZMQ

Crystal structure of Zika NS3 protease with phenylacetyl-Lys-Lys-Arg-COOH inhibitor
分子名称:	Serine protease NS3, Serine protease subunit NS2B, peptide PAC-DLY-DLY-DAR
著者	Phoo, W.W, Wirawan, M.
登録日	2018-04-05
公開日	2018-10-17
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.987 Å)
主引用文献	Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors. Antiviral Res., 160, 2018

5ZMS

Crystal structure of Zika NS3 protease in complex with 4-guanidinomethyl-phenylacetyl-Lys-Lys-Arg-H
分子名称:	4-guanidinomethyl-phenylacetyl-Lys-Lys-Arg-H, NS3 protease, Serine protease subunit NS2B
著者	Phoo, W.W, Wirawan, M.
登録日	2018-04-05
公開日	2018-10-17
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors. Antiviral Res., 160, 2018

5YW1

Crystal structure of full length NS3 protein (eD4NS2BNS3) in complex with Bovine Pancreatic Trypsin Inhibitor
分子名称:	FLAVIVIRUS_NS2B, PTI protein, Peptidase S7
著者	Phoo, W.W, El Sahili, A.
登録日	2017-11-28
公開日	2019-01-02
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain To Be Published

5YVU

Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
分子名称:	GLYCEROL, Genome polyprotein, Pancreatic trypsin inhibitor
著者	Phoo, W.W, El Sahili, A.
登録日	2017-11-27
公開日	2018-11-28
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.491 Å)
主引用文献	Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain To Be Published

5YVY

Crystal structure of unlinked full length NS3 protein (eD4NS2BNS3) from DENV4 in closed conformation
分子名称:	Genome polyprotein
著者	PHOO, W.W, El Sahili, A.
登録日	2017-11-27
公開日	2018-11-28
最終更新日	2024-03-27
実験手法	X-RAY DIFFRACTION (3.2 Å)
主引用文献	Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain To Be Published

5GPI

Crystal Structures of Unlinked NS2B-NS3 Protease from Zika Virus and Its Complex with a Reverse Peptide Inhibitor
分子名称:	NS2B cofactor, NS3 protease
著者	Phoo, W.W, Zhang, Z.Z.
登録日	2016-08-02
公開日	2016-12-14
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (1.578 Å)
主引用文献	Crystal structure of unlinked NS2B-NS3 protease from Zika virus Science, 354, 2016

5YOF

Crystal structure of zika virus NS3 protease in complex with a dipeptide inhibitor
分子名称:	(S)-2-acetamido-6-amino-N-((S)-5-guanidino-1-oxopentan-2-yl)hexanamide, NS2B cofactor, NS3 Protease
著者	Phoo, W.W, Zhang, Z.Z.
登録日	2017-10-27
公開日	2018-03-21
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.51 Å)
主引用文献	Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor Structure, 26, 2018

5YOD

Crystal structure of zika virus NS3 protease in complex with a small molecule inhibitor
分子名称:	BENZOIC ACID, NS2B cofactor, NS3 protease
著者	Phoo, W.W, Zhang, Z.Z.
登録日	2017-10-27
公開日	2018-03-21
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor Structure, 26, 2018

4V0R

DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH GTP AND SAH
分子名称:	FORMIC ACID, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
著者	Zhao, Y, Soh, S, Zheng, J, Phoo, W.W, Swaminathan, K, Cornvik, T.C, Lim, S.P, Shi, P.-Y, Lescar, J, Vasudevan, S.G, Luo, D.
登録日	2014-09-18
公開日	2015-01-28
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	A Crystal Structure of the Dengue Virus Ns5 Protein Reveals a Novel Inter-Domain Interface Essential for Protein Flexibility and Virus Replication. Plos Pathog., 11, 2015

4V0Q

Dengue Virus Full Length NS5 Complexed with SAH
分子名称:	ACETATE ION, GLYCEROL, NS5 POLYMERASE, ...
著者	Zhao, Y, Soh, S, Zheng, J, Phoo, W.W, Swaminathan, K, Cornvik, T.C, Lim, S.P, Shi, P.-Y, Lescar, J, Vasudevan, S.G, Luo, D.
登録日	2014-09-18
公開日	2015-01-28
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	A Crystal Structure of the Dengue Virus Ns5 Protein Reveals a Novel Inter-Domain Interface Essential for Protein Flexibility and Virus Replication. Plos Pathog., 11, 2015

5XC6

Dengue Virus 4 NS3 Helicase in complex with SSRNA SLA12
分子名称:	NS3 Helicase, PHOSPHATE ION, RNA (5'-R(APGPUPUPGPUPUPAPGPUPCPU)-3')
著者	Swarbrick, C.M.D, Basavannacharya, C, Chan, K.W.K, Chan, S.A, Singh, D, Wei, N, Phoo, W.W, Luo, D, Lescar, J, Vasudevan, S.G.
登録日	2017-03-22
公開日	2017-11-08
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication Nucleic Acids Res., 45, 2017

5XC7

Dengue Virus 4 NS3 Helicase D290A mutant
分子名称:	CHLORIDE ION, GLYCEROL, NS3 Helicase
著者	Swarbrick, C.M.D, Basavannacharya, C, Chan, K.W.K, Chan, S.A, Singh, D, Wei, N, Phoo, W.W, Luo, D, Lescar, J, Vasudevan, S.G.
登録日	2017-03-22
公開日	2017-11-08
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication Nucleic Acids Res., 45, 2017

7VMV

Crystal structure of Dengue NS2B-NS3 Protease after secondary cleavage
分子名称:	Core protein
著者	Quek, J.P.
登録日	2021-10-09
公開日	2022-07-06
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (3.351 Å)
主引用文献	Dynamic Interactions of Post Cleaved NS2B Cofactor and NS3 Protease Identified by Integrative Structural Approaches. Viruses, 14, 2022

5H4I

Unlinked NS2B-NS3 Protease from Zika Virus in complex with a compound fragment
分子名称:	ACETATE ION, NS2B cofactor, NS3 protease, ...
著者	Zhang, Z.Z, Li, Y.
登録日	2016-10-31
公開日	2016-12-14
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (2.004 Å)
主引用文献	Crystal structure of unlinked NS2B-NS3 protease from Zika virus Science, 354, 2016

5H6V

Structure of Zika virus protease in complex with a dipeptide inhibitor
分子名称:	(S)-2-acetamido-6-amino-N-((S)-5-guanidino-1-oxopentan-2-yl)hexanamide, Genome polyprotein
著者	Zhang, Z, Chen, M.
登録日	2016-11-15
公開日	2017-06-14
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (2.422 Å)
主引用文献	Structural Dynamics of Zika Virus NS2B-NS3 Protease Binding to Dipeptide Inhibitors Structure, 25, 2017

8WNU

ZIKV rsNS1 in complex with Fab GB5 and anti-fab nanobody
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-fab nanobody, Non-structural protein 1, ...
著者	Chew, B.L.A, Luo, D.
登録日	2023-10-06
公開日	2024-05-08
実験手法	ELECTRON MICROSCOPY (3.8 Å)
主引用文献	Structural basis of Zika virus NS1 multimerization and human antibody recognition Npj Viruses, 2, 2024

8WO0

CryoEM structure of ZIKV rsNS1 filament
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Non-structural protein 1
著者	Chew, B.L.A, Luo, D.
登録日	2023-10-06
公開日	2024-05-08
実験手法	ELECTRON MICROSCOPY (8 Å)
主引用文献	Structural basis of Zika virus NS1 multimerization and human antibody recognition Npj Viruses, 2, 2024

8WO4

ZIKV rsNS1 in complex with Fab EB9 and anti-fab nanobody
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-fab nanobody, Non-structural protein 1, ...
著者	Chew, B.L.A, Luo, D.
登録日	2023-10-06
公開日	2024-05-08
実験手法	ELECTRON MICROSCOPY (2.8 Å)
主引用文献	Structural basis of Zika virus NS1 multimerization and human antibody recognition Npj Viruses, 2, 2024

8WN8

CryoEM structure of ZIKV rsNS1
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Non-structural protein 1
著者	Chew, B.L.A, Luo, D.
登録日	2023-10-05
公開日	2024-05-08
実験手法	ELECTRON MICROSCOPY (3 Å)
主引用文献	Structural basis of Zika virus NS1 multimerization and human antibody recognition Npj Viruses, 2, 2024

8WNP

ZIKV rsNS1 in complex with Fab AA12 and anti-fab nanobody
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-fab nanobody, Non-structural protein 1, ...
著者	Chew, B.L.A, Luo, D.
登録日	2023-10-06
公開日	2024-05-08
実験手法	ELECTRON MICROSCOPY (3.1 Å)
主引用文献	Structural basis of Zika virus NS1 multimerization and human antibody recognition Npj Viruses, 2, 2024

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表示件数:	25
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