4V0R

DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH GTP AND SAH

Summary for 4V0R

• Entry DOI: 10.2210/pdb4v0r/pdb
• Related: 4V0Q
• Descriptor: NS5 POLYMERASE, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (8 entities in total)
• Functional Keywords: transferase, methyltransferase, rna-dependent rna polymerase
• Biological source: DENGUE VIRUS 3
• Total number of polymer chains: 1
• Total formula weight: 104124.78

Authors

Zhao, Y.,Soh, S.,Zheng, J.,Phoo, W.W.,Swaminathan, K.,Cornvik, T.C.,Lim, S.P.,Shi, P.-Y.,Lescar, J.,Vasudevan, S.G.,Luo, D. (deposition date: 2014-09-18, release date: 2015-01-28, Last modification date: 2024-01-10)

• Primary citation: Zhao, Y.,Soh, T.S.,Zheng, J.,Chan, K.W.K.,Phoo, W.W.,Lee, C.C.,Tay, M.Y.F.,Swaminathan, K.,Cornvik, T.C.,Lim, S.P.,Shi, P.,Lescar, J.,Vasudevan, S.G.,Luo, D.; A Crystal Structure of the Dengue Virus Ns5 Protein Reveals a Novel Inter-Domain Interface Essential for Protein Flexibility and Virus Replication.; Plos Pathog., 11:04682-, 2015; PubMed: 25775415; DOI: 10.1371/JOURNAL.PPAT.1004682

Experimental method

X-RAY DIFFRACTION (2.4 Å)