5ZMS

Crystal structure of Zika NS3 protease in complex with 4-guanidinomethyl-phenylacetyl-Lys-Lys-Arg-H

Summary for 5ZMS

Entry DOI	10.2210/pdb5zms/pdb
Related PRD ID	PRD_002298
Descriptor	Serine protease subunit NS2B, NS3 protease, 4-guanidinomethyl-phenylacetyl-Lys-Lys-Arg-H, ... (4 entities in total)
Functional Keywords	viral protease, serine protease, non-structural protein 3, zika protease, viral protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Zika virus (ZIKV) More
Total number of polymer chains	10
Total formula weight	100823.46
Authors	Phoo, W.W.,Wirawan, M. (deposition date: 2018-04-05, release date: 2018-10-17, Last modification date: 2023-11-22)
Primary citation	Phoo, W.W.,Zhang, Z.,Wirawan, M.,Chew, E.J.C.,Chew, A.B.L.,Kouretova, J.,Steinmetzer, T.,Luo, D. Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors. Antiviral Res., 160:17-24, 2018 Cited by PubMed: 30315877 DOI: 10.1016/j.antiviral.2018.10.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation