5ZMS
Crystal structure of Zika NS3 protease in complex with 4-guanidinomethyl-phenylacetyl-Lys-Lys-Arg-H
Summary for 5ZMS
Entry DOI | 10.2210/pdb5zms/pdb |
Related PRD ID | PRD_002298 |
Descriptor | Serine protease subunit NS2B, NS3 protease, 4-guanidinomethyl-phenylacetyl-Lys-Lys-Arg-H, ... (4 entities in total) |
Functional Keywords | viral protease, serine protease, non-structural protein 3, zika protease, viral protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Zika virus (ZIKV) More |
Total number of polymer chains | 10 |
Total formula weight | 100823.46 |
Authors | Phoo, W.W.,Wirawan, M. (deposition date: 2018-04-05, release date: 2018-10-17, Last modification date: 2023-11-22) |
Primary citation | Phoo, W.W.,Zhang, Z.,Wirawan, M.,Chew, E.J.C.,Chew, A.B.L.,Kouretova, J.,Steinmetzer, T.,Luo, D. Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors. Antiviral Res., 160:17-24, 2018 Cited by PubMed: 30315877DOI: 10.1016/j.antiviral.2018.10.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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