1F88
 
 | | CRYSTAL STRUCTURE OF BOVINE RHODOPSIN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MERCURY (II) ION, RETINAL, ... | | 著者 | Okada, T, Palczewski, K, Stenkamp, R.E, Miyano, M. | | 登録日 | 2000-06-29 | | 公開日 | 2000-08-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of rhodopsin: A G protein-coupled receptor.
Science, 289, 2000
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3E76
 | | Crystal structure of Wild-type GroEL with bound Thallium ions | | 分子名称: | 60 kDa chaperonin, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Kiser, P.D, Lorimer, G.H, Palczewski, K. | | 登録日 | 2008-08-17 | | 公開日 | 2009-08-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.94 Å) | | 主引用文献 | Use of thallium to identify monovalent cation binding sites in GroEL.
Acta Crystallogr.,Sect.F, 65, 2009
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5UL5
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5ULG
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2I35
 | | Crystal structure of rhombohedral crystal form of ground-state rhodopsin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, RETINAL, ... | | 著者 | Stenkamp, R.E, Le Trong, I, Lodowski, D.T, Salom, D, Palczewski, K. | | 登録日 | 2006-08-17 | | 公開日 | 2006-10-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Crystal structure of a photoactivated deprotonated intermediate of rhodopsin.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2I36
 | | Crystal structure of trigonal crystal form of ground-state rhodopsin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, Rhodopsin, ... | | 著者 | Stenkamp, R.E, Le Trong, I, Lodowski, D.T, Salom, D, Palczewski, K. | | 登録日 | 2006-08-17 | | 公開日 | 2006-10-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | | 主引用文献 | Crystal structure of a photoactivated deprotonated intermediate of rhodopsin.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2I37
 | | Crystal structure of a photoactivated rhodopsin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Rhodopsin, ... | | 著者 | Lodowski, D.T, Stenkamp, R.E, Salom, D, Le Trong, I, Palczewski, K. | | 登録日 | 2006-08-17 | | 公開日 | 2006-10-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (4.15 Å) | | 主引用文献 | Crystal structure of a photoactivated deprotonated intermediate of rhodopsin.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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5KJD
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5KK0
 | | Synechocystis ACO mutant - T136A | | 分子名称: | Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, FE (II) ION | | 著者 | Sui, X, Kiser, P.D, Palczewski, K. | | 登録日 | 2016-06-20 | | 公開日 | 2016-07-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Utilization of Dioxygen by Carotenoid Cleavage Oxygenases.
J.Biol.Chem., 290, 2015
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5KJB
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6OFJ
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5KJA
 | | Synechocystis apocarotenoid oxygenase (ACO) mutant - Trp149Ala | | 分子名称: | Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, FE (II) ION | | 著者 | Sui, X, Kiser, P.D, Palczewski, K. | | 登録日 | 2016-06-18 | | 公開日 | 2016-08-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Key Residues for Catalytic Function and Metal Coordination in a Carotenoid Cleavage Dioxygenase.
J.Biol.Chem., 291, 2016
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8FCZ
 | | Crystal structure of ground-state rhodopsin in complex with a nanobody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb2, ... | | 著者 | Salom, D, Palczewski, K, Kiser, P.D. | | 登録日 | 2022-12-01 | | 公開日 | 2023-08-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain.
Nat Commun, 14, 2023
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8FD1
 | | Crystal structure of photoactivated rhodopsin in complex with a nanobody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb2, ... | | 著者 | Salom, D, Palczewski, K, Kiser, P.D. | | 登録日 | 2022-12-01 | | 公開日 | 2023-08-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (4.25 Å) | | 主引用文献 | Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain.
Nat Commun, 14, 2023
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8FD0
 | | Crystal structure of bovine rod opsin in complex with a nanobody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb2, ... | | 著者 | Salom, D, Palczewski, K, Kiser, P.D. | | 登録日 | 2022-12-01 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.71 Å) | | 主引用文献 | Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain.
Nat Commun, 14, 2023
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3FSN
 | | Crystal structure of RPE65 at 2.14 angstrom resolution | | 分子名称: | FE (II) ION, Retinal pigment epithelium-specific 65 kDa protein, TETRAETHYLENE GLYCOL | | 著者 | Kiser, P.D, Lodowski, D.T, Palczewski, K. | | 登録日 | 2009-01-11 | | 公開日 | 2009-09-29 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Crystal structure of native RPE65, the retinoid isomerase of the visual cycle.
Proc.Natl.Acad.Sci.USA, 106, 2009
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4ZHK
 | | Crystal structure of RPE65 in complex with MB-002 | | 分子名称: | (1R)-1-[3-(cyclohexylmethoxy)phenyl]propane-1,3-diol, (1S)-1-[3-(cyclohexylmethoxy)phenyl]propane-1,3-diol, FE (II) ION, ... | | 著者 | Kiser, P.D, Palczewski, K. | | 登録日 | 2015-04-25 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
J.Clin.Invest., 125, 2015
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6MZB
 | | Cryo-EM structure of phosphodiesterase 6 | | 分子名称: | GUANOSINE-3',5'-MONOPHOSPHATE, MAGNESIUM ION, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... | | 著者 | Gulati, S, Palczewski, K. | | 登録日 | 2018-11-04 | | 公開日 | 2019-03-06 | | 最終更新日 | 2021-05-19 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structure of phosphodiesterase 6 reveals insights into the allosteric regulation of type I phosphodiesterases.
Sci Adv, 5, 2019
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2NWC
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7MOR
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7MP2
 | | CRYSTAL STRUCTURE OF NATIVE BOVINE ARRESTIN 1 IN COMPLEX WITH 1D-MYO-INOSITOL 1,5-BISDIPHOSPHATE TETRAKISPHOSPHATE (1,5-PP IP4) | | 分子名称: | (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)], S-arrestin | | 著者 | Sander, C.L, Palczewski, K, Kiser, P.D. | | 登録日 | 2021-05-04 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural evidence for visual arrestin priming via complexation of phosphoinositols.
Structure, 30, 2022
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7MP0
 | | CRYSTAL STRUCTURE OF NATIVE BOVINE ARRESTIN 1 IN COMPLEX WITH 1D-MYO-INOSITOL 5-DIPHOSPHATE PENTAKISPHOSPHATE (5-PP IP5) | | 分子名称: | (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, 2-ETHOXYETHANOL, S-arrestin | | 著者 | Sander, C.L, Palczewski, K, Kiser, P.D. | | 登録日 | 2021-05-04 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural evidence for visual arrestin priming via complexation of phosphoinositols.
Structure, 30, 2022
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7MP1
 | | CRYSTAL STRUCTURE OF NATIVE BOVINE ARRESTIN 1 IN COMPLEX WITH 1,5-DI-METHYLENEBISPHOSPHONATE INOSITOL TETRAKISPHOSPHATE (1,5-PCP-IP4) | | 分子名称: | S-arrestin, {[(1R,3S,4S,5R,6S)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl]bis[oxy(hydroxyphosphoryl)methanediyl]}bis(phosphonic acid) | | 著者 | Sander, C.L, Palczewski, K, Kiser, P.D. | | 登録日 | 2021-05-04 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Structural evidence for visual arrestin priming via complexation of phosphoinositols.
Structure, 30, 2022
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4CJ6
 | | Crystal structure of the complex of the Cellular Retinal Binding Protein Mutant R234W with 9-cis-retinal | | 分子名称: | RETINAL, RETINALDEHYDE-BINDING PROTEIN 1 | | 著者 | Bolze, C.S, Helbling, R.E, Owen, R.L, Pearson, A.R, Pompidor, G, Dworkowski, F, Fuchs, M.R, Furrer, J, Golczak, M, Palczewski, K, Cascella, M, Stocker, A. | | 登録日 | 2013-12-19 | | 公開日 | 2014-01-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.896 Å) | | 主引用文献 | Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9-Cis-Retinal Isomerase Activity.
J.Am.Chem.Soc., 136, 2014
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4CIZ
 | | Crystal structure of the complex of the Cellular Retinal Binding Protein with 9-cis-retinal | | 分子名称: | L(+)-TARTARIC ACID, RETINAL, RETINALDEHYDE-BINDING PROTEIN 1 | | 著者 | Bolze, C.S, Helbling, R.E, Owen, R.L, Pearson, A.R, Pompidor, G, Dworkowski, F, Fuchs, M.R, Furrer, J, Golczak, M, Palczewski, K, Cascella, M, Stocker, A. | | 登録日 | 2013-12-18 | | 公開日 | 2014-01-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.403 Å) | | 主引用文献 | Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9-Cis-Retinal Isomerase Activity.
J.Am.Chem.Soc., 136, 2014
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