5UL5
Crystal structure of RPE65 in complex with MB-004 and palmitate
Summary for 5UL5
| Entry DOI | 10.2210/pdb5ul5/pdb |
| Related | 5ulg |
| Descriptor | Retinoid isomerohydrolase, FE (II) ION, PALMITIC ACID, ... (7 entities in total) |
| Functional Keywords | retinoid isomerase, non-heme iron enzyme, inhibitor, isomerase, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor |
| Biological source | Bos taurus (Bovine) |
| Total number of polymer chains | 2 |
| Total formula weight | 123842.41 |
| Authors | Kiser, P.D.,Palczewski, K. (deposition date: 2017-01-24, release date: 2017-05-17, Last modification date: 2023-10-04) |
| Primary citation | Kiser, P.D.,Zhang, J.,Badiee, M.,Kinoshita, J.,Peachey, N.S.,Tochtrop, G.P.,Palczewski, K. Rational Tuning of Visual Cycle Modulator Pharmacodynamics. J. Pharmacol. Exp. Ther., 362:131-145, 2017 Cited by PubMed: 28476927DOI: 10.1124/jpet.117.240721 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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