5UL5
Crystal structure of RPE65 in complex with MB-004 and palmitate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Retinoid isomerohydrolase | polymer | 533 | 61040.2 | 2 | UniProt (Q28175) Pfam (PF03055) In PDB | Bos taurus (Bovine) | All-trans-retinyl-palmitate hydrolase,Retinal pigment epithelium-specific 65 kDa protein,Retinol isomerase |
| 2 | A, B | FE (II) ION | non-polymer | 55.8 | 2 | Chemie (FE2) | |||
| 3 | A, B | PALMITIC ACID | non-polymer | 256.4 | 2 | Chemie (PLM) | |||
| 4 | A, B | (1R)-3-amino-1-{3-[(2-propylpentyl)oxy]phenyl}propan-1-ol | non-polymer | 279.4 | 2 | Chemie (8D7) | |||
| 5 | A, B | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | A, B | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE | non-polymer | 266.3 | 2 | Chemie (PG6) | |||
| 7 | water | water | 18.0 | 447 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 533 (UniProt: Q28175)
| PDB | External Database | Details |
|---|---|---|
| Leu 341 | Ser 341 | see remark 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 122080.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1762.0 | |
| All* | Total formula weight | 123842.4 |
