3V8U
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3V89
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![BU of 3v89 by Molmil](/molmil-images/mine/3v89) | The crystal structure of transferrin binding protein A (TbpA) from Neisseria meningitidis serogroup B in complex with the C-lobe of human transferrin | 分子名称: | Serotransferrin, Transferrin-binding protein A | 著者 | Noinaj, N, Oke, M, Easley, N, Zak, O, Aisen, P, Buchanan, S.K. | 登録日 | 2011-12-22 | 公開日 | 2012-02-15 | 最終更新日 | 2012-04-18 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis for iron piracy by pathogenic Neisseria. Nature, 483, 2012
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3V8X
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![BU of 3v8x by Molmil](/molmil-images/mine/3v8x) | The crystal structure of transferrin binding protein A (TbpA) from Neisserial meningitidis serogroup B in complex with full length human transferrin | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Noinaj, N, Easley, N, Buchanan, S.K. | 登録日 | 2011-12-23 | 公開日 | 2012-02-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for iron piracy by pathogenic Neisseria. Nature, 483, 2012
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3V83
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![BU of 3v83 by Molmil](/molmil-images/mine/3v83) | The 2.1 angstrom crystal structure of diferric human transferrin | 分子名称: | BICARBONATE ION, FE (III) ION, HEXAETHYLENE GLYCOL, ... | 著者 | Noinaj, N, Steere, A, Mason, A.B, Buchanan, S.K. | 登録日 | 2011-12-22 | 公開日 | 2012-02-15 | 最終更新日 | 2012-04-18 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | Structural basis for iron piracy by pathogenic Neisseria. Nature, 483, 2012
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3POP
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![BU of 3pop by Molmil](/molmil-images/mine/3pop) | The crystal structure of GilR, an oxidoreductase that catalyzes the terminal step of gilvocarcin biosynthesis | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GilR oxidase | 著者 | Noinaj, N, Bosserman, M.A, Schickli, M.A, Kharel, M.K, Rohr, J, Buchanan, S.K. | 登録日 | 2010-11-23 | 公開日 | 2011-05-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | 主引用文献 | The Crystal Structure and Mechanism of an Unusual Oxidoreductase, GilR, Involved in Gilvocarcin V Biosynthesis. J.Biol.Chem., 286, 2011
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4K3B
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![BU of 4k3b by Molmil](/molmil-images/mine/4k3b) | The crystal structure of BamA from Neisseria gonorrhoeae | 分子名称: | Outer membrane protein assembly factor BamA | 著者 | Noinaj, N, Lukacik, P, Chang, H, Easley, N, Buchanan, S.K. | 登録日 | 2013-04-10 | 公開日 | 2013-09-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural insight into the biogenesis of beta-barrel membrane proteins. Nature, 501, 2013
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4K3C
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![BU of 4k3c by Molmil](/molmil-images/mine/4k3c) | The crystal structure of BamA from Haemophilus ducreyi lacking POTRA domains 1-3 | 分子名称: | Outer membrane protein assembly factor BamA | 著者 | Noinaj, N, Lukacik, P, Chang, H, Easley, N, Buchanan, S.K. | 登録日 | 2013-04-10 | 公開日 | 2013-09-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.913 Å) | 主引用文献 | Structural insight into the biogenesis of beta-barrel membrane proteins. Nature, 501, 2013
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3SKP
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![BU of 3skp by Molmil](/molmil-images/mine/3skp) | The structure of apo-human transferrin C-lobe with bound sulfate ions | 分子名称: | SULFATE ION, Serotransferrin | 著者 | Noinaj, N, Steere, A.N, Mason, A.B, Buchanan, S.K. | 登録日 | 2011-06-22 | 公開日 | 2012-02-15 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis for iron piracy by pathogenic Neisseria. Nature, 483, 2012
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3PQB
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![BU of 3pqb by Molmil](/molmil-images/mine/3pqb) | The crystal structure of pregilvocarcin in complex with GilR, an oxidoreductase that catalyzes the terminal step of gilvocarcin biosynthesis | 分子名称: | (1R)-1,4-anhydro-6-deoxy-1-[(6R)-8-ethenyl-1,6-dihydroxy-10,12-dimethoxy-6H-dibenzo[c,h]chromen-4-yl]-D-galactitol, FLAVIN-ADENINE DINUCLEOTIDE, Putative oxidoreductase | 著者 | Noinaj, N, Bosserman, M.A, Schickli, M.A, Kharel, M.K, Rohr, J, Buchanan, S.K. | 登録日 | 2010-11-25 | 公開日 | 2011-05-11 | 最終更新日 | 2011-08-03 | 実験手法 | X-RAY DIFFRACTION (2.324 Å) | 主引用文献 | The Crystal Structure and Mechanism of an Unusual Oxidoreductase, GilR, Involved in Gilvocarcin V Biosynthesis. J.Biol.Chem., 286, 2011
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3Q7O
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3Q7M
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3Q7N
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3U0O
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![BU of 3u0o by Molmil](/molmil-images/mine/3u0o) | The crystal structure of selenophosphate synthetase from E. coli | 分子名称: | MAGNESIUM ION, Selenide, water dikinase | 著者 | Noinaj, N, Wattanasak, R, Wally, J, Stadtman, T, Buchanan, S.K. | 登録日 | 2011-09-28 | 公開日 | 2012-03-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural insights into the catalytic mechanism of Escherichia coli selenophosphate synthetase. J.Bacteriol., 194, 2012
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6DTN
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6WH8
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![BU of 6wh8 by Molmil](/molmil-images/mine/6wh8) | The structure of NTMT1 in complex with compound BM-30 | 分子名称: | 4HP-PRO-LYS-ARG-NH2, BM-30, N-terminal Xaa-Pro-Lys N-methyltransferase 1, ... | 著者 | Noinaj, N, Chen, D, Huang, R. | 登録日 | 2020-04-07 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.729 Å) | 主引用文献 | Selective Peptidomimetic Inhibitors of NTMT1/2: Rational Design, Synthesis, Characterization, and Crystallographic Studies. J.Med.Chem., 63, 2020
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4GRV
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![BU of 4grv by Molmil](/molmil-images/mine/4grv) | The crystal structure of the neurotensin receptor NTS1 in complex with neurotensin (8-13) | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Neurotensin 8-13, Neurotensin receptor type 1, ... | 著者 | Noinaj, N, White, J.F, Shibata, Y, Love, J, Kloss, B, Xu, F, Gvozdenovic-Jeremic, J, Shah, P, Shiloach, J, Tate, C.G, Grisshammer, R. | 登録日 | 2012-08-27 | 公開日 | 2012-10-17 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | Structure of the agonist-bound neurotensin receptor. Nature, 490, 2012
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3FMW
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![BU of 3fmw by Molmil](/molmil-images/mine/3fmw) | The crystal structure of MtmOIV, a Baeyer-Villiger monooxygenase from the mithramycin biosynthetic pathway in Streptomyces argillaceus. | 分子名称: | 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, Oxygenase | 著者 | Noinaj, N, Beam, M.P, Wang, C, Rohr, J. | 登録日 | 2008-12-22 | 公開日 | 2009-05-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Crystal structure of Baeyer-Villiger monooxygenase MtmOIV, the key enzyme of the mithramycin biosynthetic pathway . Biochemistry, 48, 2009
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6PVB
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![BU of 6pvb by Molmil](/molmil-images/mine/6pvb) | The structure of NTMT1 in complex with compound 6 | 分子名称: | AMINO GROUP-()-(2~{S})-2-azanylpropanal-()-ISOLEUCINE-()-ARGININE-()-LYSINE-()-PROLINE-()-AMINO-ACETALDEHYDE-()-9-(5-{[(3S)-3-amino-3-carboxypropyl](pentyl)amino}-5-deoxy-beta-L-arabinofuranosyl)-9H-purin-6-amine, N-terminal Xaa-Pro-Lys N-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Noinaj, N, Chen, D, Huang, R. | 登録日 | 2019-07-20 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Probing the Plasticity in the Active Site of Protein N-terminal Methyltransferase 1 Using Bisubstrate Analogues. J.Med.Chem., 63, 2020
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6PVS
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![BU of 6pvs by Molmil](/molmil-images/mine/6pvs) | Structure of Nicotinamide N-Methyltransferase (NNMT) in complex with inhibitor LL320 | 分子名称: | 9-(5-{[(3R)-3-amino-3-carboxypropyl][3-(3-carbamoylphenyl)prop-2-yn-1-yl]amino}-5-deoxy-alpha-D-lyxofuranosyl)-9H-purin-6-amine, NNMT protein | 著者 | Noinaj, N, Huang, R, Chen, D, Yadav, R. | 登録日 | 2019-07-21 | 公開日 | 2019-11-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.575 Å) | 主引用文献 | Novel Propargyl-Linked Bisubstrate Analogues as Tight-Binding Inhibitors for NicotinamideN-Methyltransferase. J.Med.Chem., 62, 2019
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6PVA
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![BU of 6pva by Molmil](/molmil-images/mine/6pva) | The structure of NTMT1 in complex with compound 11 | 分子名称: | AMINO GROUP-()-LYSINE-()-LYSINE-()-PROLINE-()-AMINO-ACETALDEHYDE-()-5'-{[(3S)-3-amino-3-carboxypropyl](3-aminopropyl)amino}-5'-deoxyadenosine, N-terminal Xaa-Pro-Lys N-methyltransferase 1 | 著者 | Noinaj, N, Chen, D, Huang, R. | 登録日 | 2019-07-20 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | The structure of NTMT1 in complex with compound 11 To Be published
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6PVE
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![BU of 6pve by Molmil](/molmil-images/mine/6pve) | Structure of Nicotinamide N-Methyltransferase (NNMT) in complex with inhibitor LL319 | 分子名称: | 9-(5-{[(3S)-3-amino-3-carboxypropyl][3-(3-carbamoylphenyl)propyl]amino}-5-deoxy-alpha-D-ribofuranosyl)-9H-purin-6-amine, NNMT protein | 著者 | Noinaj, N, Huang, R, Chen, D, Yadav, R. | 登録日 | 2019-07-20 | 公開日 | 2019-11-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Novel Propargyl-Linked Bisubstrate Analogues as Tight-Binding Inhibitors for NicotinamideN-Methyltransferase. J.Med.Chem., 62, 2019
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3P7L
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3P7O
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5DPL
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![BU of 5dpl by Molmil](/molmil-images/mine/5dpl) | The structure of PKMT2 from Rickettsia typhi in complex with AdoHcy | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, protein lysine methyltransferase 2 | 著者 | Noinaj, N, Abeykoon, A, He, Y, Yang, D.C, Buchanan, S.K. | 登録日 | 2015-09-12 | 公開日 | 2016-08-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural Insights into Substrate Recognition and Catalysis in Outer Membrane Protein B (OmpB) by Protein-lysine Methyltransferases from Rickettsia. J.Biol.Chem., 291, 2016
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5DNK
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![BU of 5dnk by Molmil](/molmil-images/mine/5dnk) | The structure of PKMT1 from Rickettsia prowazekii in complex with AdoHcy | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, protein lysine methyltransferase 1 | 著者 | Noinaj, N, Abeykoon, A, He, Y, Yang, D.C, Buchanan, S.K. | 登録日 | 2015-09-10 | 公開日 | 2016-08-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Insights into Substrate Recognition and Catalysis in Outer Membrane Protein B (OmpB) by Protein-lysine Methyltransferases from Rickettsia. J.Biol.Chem., 291, 2016
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