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6DTN

The structure of NTMT1 in complex with compound DC100-1

Summary for 6DTN
Entry DOI10.2210/pdb6dtn/pdb
Related PRD IDPRD_002319
DescriptorN-terminal Xaa-Pro-Lys N-methyltransferase 1, (6D6)PPKRIA(NH2), DC100-1 (3 entities in total)
Functional Keywordsmethyltransferase, enzyme, inhibitor complex, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight28407.38
Authors
Noinaj, N.,Chen, D.,Huang, R. (deposition date: 2018-06-18, release date: 2019-04-03, Last modification date: 2023-10-11)
Primary citationChen, D.,Dong, G.,Noinaj, N.,Huang, R.
Discovery of Bisubstrate Inhibitors for Protein N-Terminal Methyltransferase 1.
J. Med. Chem., 62:3773-3779, 2019
Cited by
PubMed: 30883119
DOI: 10.1021/acs.jmedchem.9b00206
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.475 Å)
Structure validation

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