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Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel
分子名称:	Uncharacterized protein
著者	Li, Q, Ng, H.
登録日	2013-11-21
公開日	2014-04-02
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel. J.Struct.Biol., 186, 2014

7M1X

Cryo-EM Structure of Nucleosome containing mouse histone variant H2A.Z
分子名称:	DNA (136-MER), Histone H2A.Z, Histone H2B 1.1, ...
著者	Tan, D, Lewis, T.
登録日	2021-03-15
公開日	2021-09-29
最終更新日	2024-05-29
実験手法	ELECTRON MICROSCOPY (3.7 Å)
主引用文献	Structural basis of chromatin regulation by histone variant H2A.Z. Nucleic Acids Res., 49, 2021

5LB2

Apo-structure of humanised RadA-mutant humRadA2
分子名称:	DNA repair and recombination protein RadA
著者	Marsh, M, Fischer, G, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日	2016-06-15
公開日	2016-10-19
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016

5BOC

Crystal structure of topoisomerase ParE inhibitor
分子名称:	3-methyl-4-({3-[3-methyl-5-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl}carbamoyl)benzoic acid, DNA topoisomerase 4 subunit B
著者	Tan, Y.W, Chen, G.Y, Hung, A.W, Hill, J.
登録日	2015-05-27
公開日	2015-06-17
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Application of Fragment-based Drug Discovery against DNA GyraseB To be published

4OJ0

mCardinal V218E
分子名称:	Fluorescent protein FP480
著者	Ataie, N, Ng, H.
登録日	2014-01-20
公開日	2014-03-19
最終更新日	2014-05-14
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Non-invasive intravital imaging of cellular differentiation with a bright red-excitable fluorescent protein. Nat.Methods, 11, 2014

2N7G

Structure of the cyclic nucleotide-binding homology domain of the hERG channel
分子名称:	Potassium voltage-gated channel subfamily H member 2
著者	Li, Y, Ng, H, Li, Q, Kang, C.
登録日	2015-09-10
公開日	2016-05-18
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Structure of the Cyclic Nucleotide-Binding Homology Domain of the hERG Channel and Its Insight into Type 2 Long QT Syndrome Sci Rep, 6, 2016

5J4K

Structure of humanised RadA-mutant humRadA22F in complex with 1-Indane-6-carboxylic acid
分子名称:	2,3-dihydro-1H-indene-2-carboxylic acid, CALCIUM ION, DNA repair and recombination protein RadA, ...
著者	Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日	2016-04-01
公開日	2016-10-26
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (1.346 Å)
主引用文献	Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016

5JEC

Apo-structure of humanised RadA-mutant humRadA33F
分子名称:	CHLORIDE ION, DNA repair and recombination protein RadA, SULFATE ION
著者	Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日	2016-04-18
公開日	2016-10-19
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.34 Å)
主引用文献	Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016

5JED

Apo-structure of humanised RadA-mutant humRadA28
分子名称:	(4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ...
著者	Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日	2016-04-18
公開日	2016-10-19
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.332 Å)
主引用文献	Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016

5KDD

Apo-structure of humanised RadA-mutant humRadA22
分子名称:	DNA repair and recombination protein RadA, SULFATE ION
著者	Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日	2016-06-08
公開日	2016-10-19
最終更新日	2024-06-19
実験手法	X-RAY DIFFRACTION (1.99 Å)
主引用文献	Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016

5J4L

Apo-structure of humanised RadA-mutant humRadA22F
分子名称:	CHLORIDE ION, DNA repair and recombination protein RadA
著者	Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日	2016-04-01
公開日	2016-10-19
最終更新日	2024-06-19
実験手法	X-RAY DIFFRACTION (1.13 Å)
主引用文献	Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016

5JEE

Apo-structure of humanised RadA-mutant humRadA26F
分子名称:	CALCIUM ION, DNA repair and recombination protein RadA
著者	Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日	2016-04-18
公開日	2016-10-19
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.49 Å)
主引用文献	Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016

5J4H

Structure of humanised RadA-mutant humRadA22F in complex with indole-6-carboxylic acid
分子名称:	1H-indole-6-carboxylic acid, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者	Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日	2016-04-01
公開日	2016-10-19
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (1.374 Å)
主引用文献	Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016

5L8V

Apo-structure of humanised RadA-mutant humRadA4
分子名称:	DNA repair and recombination protein RadA, PHOSPHATE ION
著者	Marsh, M, Fischer, G, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日	2016-06-08
公開日	2016-10-19
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016

5LB4

Apo-structure of humanised RadA-mutant humRadA14
分子名称:	DNA repair and recombination protein RadA
著者	Marsh, M, Fischer, G, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日	2016-06-15
公開日	2016-10-19
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.98 Å)
主引用文献	Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016

5LBI

Apo-structure of humanised RadA-mutant humRadA3
分子名称:	CALCIUM ION, DNA repair and recombination protein RadA
著者	Marsh, M, Fischer, G, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日	2016-06-16
公開日	2016-10-26
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.43 Å)
主引用文献	Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016

7UO4

SARS-CoV-2 replication-transcription complex bound to Remdesivir triphosphate, in a pre-catalytic state
分子名称:	MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ...
著者	Malone, B.F, Perry, J.K, Appleby, T.C, Feng, J.Y, Campbell, E.A, Darst, S.A.
登録日	2022-04-12
公開日	2022-11-30
最終更新日	2023-03-08
実験手法	ELECTRON MICROSCOPY (3.38 Å)
主引用文献	Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature, 614, 2023

7UOB

SARS-CoV-2 replication-transcription complex bound to GTP, in a pre-catalytic state
分子名称:	3'-DEOXYURIDINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者	Malone, B.F, Perry, J.K, Appleby, T.C, Feng, J.Y, Campbell, E.A, Darst, S.A.
登録日	2022-04-12
公開日	2022-11-30
最終更新日	2024-06-12
実験手法	ELECTRON MICROSCOPY (2.68 Å)
主引用文献	Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature, 614, 2023

7UO9

SARS-CoV-2 replication-transcription complex bound to UTP, in a pre-catalytic state
分子名称:	MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ...
著者	Malone, B.F, Perry, J.K, Appleby, T.C, Feng, J.Y, Campbell, E.A, Darst, S.A.
登録日	2022-04-12
公開日	2022-11-30
最終更新日	2024-06-12
実験手法	ELECTRON MICROSCOPY (3.13 Å)
主引用文献	Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature, 614, 2023

7UO7

SARS-CoV-2 replication-transcription complex bound to ATP, in a pre-catalytic state
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Non-structural protein 7, ...
著者	Malone, B.F, Perry, J.K, Appleby, T.C, Feng, J.Y, Campbell, E.A, Darst, S.A.
登録日	2022-04-12
公開日	2022-11-30
最終更新日	2024-06-12
実験手法	ELECTRON MICROSCOPY (3.09 Å)
主引用文献	Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature, 614, 2023

7UOE

SARS-CoV-2 replication-transcription complex bound to CTP, in a pre-catalytic state
分子名称:	3'-DEOXYURIDINE-5'-MONOPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者	Malone, B.F, Perry, J.K, Appleby, T.C, Feng, J.Y, Campbell, E.A, Darst, S.A.
登録日	2022-04-12
公開日	2022-11-30
最終更新日	2024-06-12
実験手法	ELECTRON MICROSCOPY (2.67 Å)
主引用文献	Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature, 614, 2023

5JFG

Structure of humanised RadA-mutant humRadA22F in complex with peptide FHTA
分子名称:	CALCIUM ION, DIMETHYL SULFOXIDE, DNA repair and recombination protein RadA, ...
著者	Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日	2016-04-19
公開日	2016-10-26
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (1.77 Å)
主引用文献	Humanisation of RadA from Pyrococcus furiosus To Be Published

全ヒット件数:	22
表示件数:	22
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