5L8V

Apo-structure of humanised RadA-mutant humRadA4

Summary for 5L8V

Entry DOI	10.2210/pdb5l8v/pdb
Descriptor	DNA repair and recombination protein RadA, PHOSPHATE ION (3 entities in total)
Functional Keywords	dna repair, fragment based drug design, humanisation, hydrolase
Biological source	Pyrococcus furiosus
Total number of polymer chains	1
Total formula weight	24968.40
Authors	Marsh, M.,Fischer, G.,Moschetti, T.,Sharpe, T.,Scott, D.,Morgan, M.,Ng, H.,Skidmore, J.,Venkitaraman, A.,Abell, C.,Blundell, T.L.,Hyvonen, M. (deposition date: 2016-06-08, release date: 2016-10-19, Last modification date: 2024-02-07)
Primary citation	Moschetti, T.,Sharpe, T.,Fischer, G.,Marsh, M.E.,Ng, H.K.,Morgan, M.,Scott, D.E.,Blundell, T.L.,R Venkitaraman, A.,Skidmore, J.,Abell, C.,Hyvonen, M. Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428:4589-4607, 2016 Cited by PubMed: 27725183 DOI: 10.1016/j.jmb.2016.10.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation