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1IFY
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BU of 1ify by Molmil
Solution Structure of the Internal UBA Domain of HHR23A
分子名称: UV EXCISION REPAIR PROTEIN RAD23 HOMOLOG A
著者Mueller, T.D, Feigon, J.
登録日2001-04-13
公開日2002-07-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structures of UBA domains reveal a conserved hydrophobic surface for protein-protein interactions.
J.Mol.Biol., 319, 2002
1P98
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BU of 1p98 by Molmil
High-resolution NMR structure of the Ubl-domain of HHR23A
分子名称: UV excision repair protein RAD23 homolog A
著者Mueller, T.D, Feigon, J.
登録日2003-05-09
公開日2003-10-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural determinants for the binding of ubiquitin-like domains to the proteasome.
Embo J., 22, 2003
1P9D
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BU of 1p9d by Molmil
High-resolution structure of the complex of HHR23A ubiquitin-like domain and the C-terminal ubiquitin-interacting motif of proteasome subunit S5a
分子名称: 26S proteasome non-ATPase regulatory subunit 4, UV excision repair protein RAD23 homolog A
著者Mueller, T.D, Feigon, J.
登録日2003-05-10
公開日2003-10-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural determinants for the binding of ubiquitin-like domains to the proteasome.
Embo J., 22, 2003
1P9C
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BU of 1p9c by Molmil
NMR solution structure of the C-terminal ubiquitin-interacting motif of the proteasome subunit S5a
分子名称: 26S proteasome non-ATPase regulatory subunit 4
著者Mueller, T.D, Feigon, J.
登録日2003-05-10
公開日2003-10-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural determinants for the binding of ubiquitin-like domains to the proteasome.
Embo J., 22, 2003
1RAX
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BU of 1rax by Molmil
RA-DOMAIN OF RAL GUANOSINE-NUCLEOTIDE DISSOCIATION STIMULATOR
分子名称: PROTEIN (RA-DOMAIN OF RAL GUANOSINE DISSOCIATION STIMULATOR)
著者Mueller, T.D, Handel, L, Schmieder, P, Oschkinat, H.
登録日1999-03-13
公開日1999-03-19
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献High-Resolution Structure of the Ra-Domain of Human Ralgds and a Dynamics Study of its Binding Loop to Ras
To be Published
1WAQ
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BU of 1waq by Molmil
Crystal structure of human Growth and Differentiation Factor 5 (GDF-5)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GROWTH/DIFFERENTIATION FACTOR 5
著者Mueller, T.D, Nickel, J, Sebald, W.
登録日2004-10-27
公開日2005-05-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献A Single Residue of Gdf-5 Defines Binding Specificity to Bmp Receptor Ib.
J.Mol.Biol., 349, 2005
3B5K
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BU of 3b5k by Molmil
Crystal structure of murine interleukin-5
分子名称: Interleukin-5
著者Mueller, T.D, Patino, E.
登録日2007-10-26
公開日2008-11-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of murine interleukin-5
To be Published
3BK3
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BU of 3bk3 by Molmil
Crystal structure of the complex of BMP-2 and the first Von Willebrand domain type C of Crossveinless-2
分子名称: Bone morphogenetic protein 2, Crossveinless 2
著者Mueller, T.D, Sebald, W, Zhang, J.-L.
登録日2007-12-05
公開日2008-05-27
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding
Dev.Cell, 14, 2008
2H62
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BU of 2h62 by Molmil
Crystal structure of a ternary ligand-receptor complex of BMP-2
分子名称: Acvr2b protein, Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
著者Mueller, T.D.
登録日2006-05-30
公開日2007-04-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor.
Bmc Struct.Biol., 7, 2007
2H64
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BU of 2h64 by Molmil
Crystal structure of a ternary ligand-receptor complex of BMP-2
分子名称: Acvr2b protein, Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
著者Mueller, T.D, Sebald, W, Weber, D.
登録日2006-05-30
公開日2007-04-10
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor.
Bmc Struct.Biol., 7, 2007
6H41
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BU of 6h41 by Molmil
Structure of the complex of the IL-5 inhibitory peptide AF17121 bound to the IL-5 receptor IL-5Ralpha
分子名称: Interleukin-5 receptor subunit alpha, VAL-ASP-GLU-CYS-TRP-ARG-ILE-ILE-ALA-SER-HIS-THR-TRP-PHE-CYS-ALA-GLU-GLU
著者Mueller, T.D, Scheide, J.P.
登録日2018-07-20
公開日2018-12-26
最終更新日2019-02-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural Basis of Interleukin-5 Inhibition by the Small Cyclic Peptide AF17121.
J. Mol. Biol., 431, 2019
5DR5
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BU of 5dr5 by Molmil
Crystal structure of the sclerostin-neutralizing Fab AbD09097
分子名称: AbD09097 Fab heavy chain, AbD09097 Fab light chain
著者Mueller, T.D, Boschert, V, Weidauer, S.E, Muth, E.M, Knappik, A, Frisch, C.
登録日2015-09-15
公開日2016-08-31
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Generation and Affinity Maturation of Neutralizing Anti-Sclerostin Antibodies
to be published
2MBK
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BU of 2mbk by Molmil
The Clip-segment of the von Willebrand domain 1 of the BMP modulator protein Crossveinless 2 is preformed
分子名称: Crossveinless 2
著者Mueller, T.D, Fiebig, J.E, Weidauer, S.E, Qiu, L, Bauer, M, Schmieder, P, Beerbaum, M, Zhang, J, Oschkinat, H, Sebald, W.
登録日2013-08-02
公開日2013-10-16
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Clip-Segment of the von Willebrand Domain 1 of the BMP Modulator Protein Crossveinless 2 Is Preformed.
Molecules, 18, 2013
3NH7
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BU of 3nh7 by Molmil
Crystal structure of the neutralizing Fab fragment AbD1556 bound to the BMP type I receptor IA
分子名称: Antibody fragment Fab AbD1556, heavy chain, light chain, ...
著者Mueller, T.D, Harth, S, Sebald, W.
登録日2010-06-14
公開日2010-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A selection fit mechanism in BMP receptor IA as a possible source for BMP ligand-receptor promiscuity
Plos One, 5, 2010
3QB4
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BU of 3qb4 by Molmil
Crystal structure of a TGF-beta ligand-receptor complex
分子名称: Bone morphogenetic protein receptor type-1A, Growth/differentiation factor 5
著者Mueller, T.D, Nickel, J, Sebald, W.
登録日2011-01-12
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献GDF-5 can act as a context-dependent BMP-2 antagonist.
Bmc Biol., 13, 2015
3QT2
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BU of 3qt2 by Molmil
Structure of a cytokine ligand-receptor complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Interleukin-5, Interleukin-5 receptor subunit alpha, ...
著者Mueller, T.D, Patino, E, Kotzsch, A, Saremba, S, Nickel, J, Schmitz, W, Sebald, W.
登録日2011-02-22
公開日2012-02-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure Analysis of the IL-5 Ligand-Receptor Complex Reveals a Wrench-like Architecture for IL-5Ralpha.
Structure, 19, 2011
2R52
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BU of 2r52 by Molmil
Crystal structure analysis of Bone Morphogenetic Protein-6 (BMP-6)
分子名称: Bone morphogenetic protein 6, ISOPROPYL ALCOHOL
著者Mueller, T.D, Sebald, W, Saremba, S.
登録日2007-09-03
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand.
Febs J., 275, 2007
2R53
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BU of 2r53 by Molmil
Crystal structure analysis of Bone Morphogenetic Protein-6 variant B2 (B2-BMP-6)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Bone morphogenetic protein 6
著者Mueller, T.D, Sebald, W.
登録日2007-09-03
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand.
Febs J., 275, 2007
3SS7
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BU of 3ss7 by Molmil
Crystal structure of holo D-serine dehydratase from Escherichia coli at 1.55 A resolution
分子名称: D-serine dehydratase, GLYCEROL, POTASSIUM ION, ...
著者Urusova, D.V, Isupov, M.N, Antonyuk, S.V, Kachalova, G.S, Vagin, A.A, Lebedev, A.A, Bourenkov, G.P, Dauter, Z, Bartunik, H.D, Melik-Adamyan, W.R, Mueller, T.D, Schnackerz, K.D.
登録日2011-07-07
公開日2012-01-18
最終更新日2012-02-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of D-serine dehydratase from Escherichia coli.
Biochim.Biophys.Acta, 1824, 2011
3SS9
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BU of 3ss9 by Molmil
Crystal structure of holo D-serine dehydratase from Escherichia coli at 1.97 A resolution
分子名称: D-serine dehydratase, POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE
著者Urusova, D.V, Isupov, M.N, Antonyuk, S.V, Kachalova, G.S, Vagin, A.A, Lebedev, A.A, Bourenkov, G.P, Dauter, Z, Bartunik, H.D, Melik-Adamyan, W.R, Mueller, T.D, Schnackerz, K.D.
登録日2011-07-08
公開日2012-01-18
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Crystal structure of D-serine dehydratase from Escherichia coli.
Biochim.Biophys.Acta, 1824, 2011
2KD3
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BU of 2kd3 by Molmil
NMR structure of the Wnt modulator protein Sclerostin
分子名称: Sclerostin
著者Weidauer, S.E, Mueller, T.D.
登録日2009-01-02
公開日2009-02-10
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献NMR structure of the Wnt modulator protein Sclerostin
Biochem.Biophys.Res.Commun., 380, 2009
1F4I
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BU of 1f4i by Molmil
SOLUTION STRUCTURE OF THE HHR23A UBA(2) MUTANT P333E, DEFICIENT IN BINDING THE HIV-1 ACCESSORY PROTEIN VPR
分子名称: UV EXCISION REPAIR PROTEIN PROTEIN RAD23 HOMOLOG A
著者Withers-Ward, E.S, Mueller, T.D, Chen, I.S, Feigon, J.
登録日2000-06-07
公開日2000-12-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Biochemical and structural analysis of the interaction between the UBA(2) domain of the DNA repair protein HHR23A and HIV-1 Vpr.
Biochemistry, 39, 2000
2D48
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BU of 2d48 by Molmil
Crystal structure of the Interleukin-4 variant T13D
分子名称: Interleukin-4, SULFATE ION
著者Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
登録日2005-10-11
公開日2006-05-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
1RKJ
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BU of 1rkj by Molmil
Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target
分子名称: 5'-R(*GP*GP*AP*UP*GP*CP*CP*UP*CP*CP*CP*GP*AP*GP*UP*GP*CP*AP*UP*CP*C)-3', Nucleolin
著者Johansson, C, Finger, L.D, Trantirek, L, Mueller, T.D, Kim, S, Laird-Offringa, I.A, Feigon, J.
登録日2003-11-21
公開日2004-04-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target.
J.Mol.Biol., 337, 2004
1REU
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BU of 1reu by Molmil
Structure of the bone morphogenetic protein 2 mutant L51P
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, bone morphogenetic protein 2
著者Keller, S, Nickel, J, Zhang, J.-L, Sebald, W, Mueller, T.D.
登録日2003-11-07
公開日2004-05-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Molecular recognition of BMP-2 and BMP receptor IA.
Nat.Struct.Mol.Biol., 11, 2004

 

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