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2R52

Crystal structure analysis of Bone Morphogenetic Protein-6 (BMP-6)

Summary for 2R52
Entry DOI10.2210/pdb2r52/pdb
Related1REW 2H62 2H64 2r53 3BMP
DescriptorBone morphogenetic protein 6, ISOPROPYL ALCOHOL (3 entities in total)
Functional Keywordsbmp-6, tgf-beta ligand, chondrogenesis, cleavage on pair of basic residues, cytokine, developmental protein, differentiation, glycoprotein, growth factor, osteogenesis, secreted
Biological sourceHomo sapiens (human)
Cellular locationSecreted (By similarity): P22004
Total number of polymer chains2
Total formula weight32793.36
Authors
Mueller, T.D.,Sebald, W.,Saremba, S. (deposition date: 2007-09-03, release date: 2008-01-15, Last modification date: 2023-08-30)
Primary citationSaremba, S.,Nickel, J.,Seher, A.,Kotzsch, A.,Sebald, W.,Mueller, T.D.
Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand.
Febs J., 275:172-183, 2007
Cited by
PubMed: 18070108
DOI: 10.1111/j.1742-4658.2007.06187.x
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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