2R52
Crystal structure analysis of Bone Morphogenetic Protein-6 (BMP-6)
Summary for 2R52
Entry DOI | 10.2210/pdb2r52/pdb |
Related | 1REW 2H62 2H64 2r53 3BMP |
Descriptor | Bone morphogenetic protein 6, ISOPROPYL ALCOHOL (3 entities in total) |
Functional Keywords | bmp-6, tgf-beta ligand, chondrogenesis, cleavage on pair of basic residues, cytokine, developmental protein, differentiation, glycoprotein, growth factor, osteogenesis, secreted |
Biological source | Homo sapiens (human) |
Cellular location | Secreted (By similarity): P22004 |
Total number of polymer chains | 2 |
Total formula weight | 32793.36 |
Authors | Mueller, T.D.,Sebald, W.,Saremba, S. (deposition date: 2007-09-03, release date: 2008-01-15, Last modification date: 2023-08-30) |
Primary citation | Saremba, S.,Nickel, J.,Seher, A.,Kotzsch, A.,Sebald, W.,Mueller, T.D. Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand. Febs J., 275:172-183, 2007 Cited by PubMed: 18070108DOI: 10.1111/j.1742-4658.2007.06187.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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