2R52

Crystal structure analysis of Bone Morphogenetic Protein-6 (BMP-6)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0008083	molecular_function	growth factor activity
B	0005576	cellular_component	extracellular region
B	0008083	molecular_function	growth factor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IPA B 133

Chain	Residue
B	ASN76

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE IPA A 133

Chain	Residue
A	LYS119
A	LYS120
A	TYR121
A	ARG122
B	ASN76

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA B 134

Chain	Residue
B	ASN69
B	ASN113
B	ASN115

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IPA B 135

Chain	Residue
A	TRP45
A	TYR109
A	TYR121
B	LYS53

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA B 136

Chain	Residue
A	ASP42
A	LEU43
B	SER106

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site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IPA B 137

Chain	Residue
B	ASN103
B	ALA104

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site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA A 134

Chain	Residue
A	ASN103
A	ALA104
A	LYS120

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site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA A 135

Chain	Residue
A	ARG32
A	HIS34
A	GLU35

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site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IPA A 136

Chain	Residue
A	ALA51
A	PRO52

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site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IPA A 137

Chain	Residue
A	ASN76
A	ILE79

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Functional Information from PROSITE/UniProt

site_id	PS00250
Number of Residues	16
Details	TGF_BETA_1 TGF-beta family signature. IiaPkgYaanyCdGeC

Chain	Residue	Details
A	ILE49-CYS64

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18070108","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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