2R53
Crystal structure analysis of Bone Morphogenetic Protein-6 variant B2 (B2-BMP-6)
Summary for 2R53
| Entry DOI | 10.2210/pdb2r53/pdb |
| Related | 1REW 2H62 2H64 2r52 3BMP |
| Descriptor | Bone morphogenetic protein 6, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total) |
| Functional Keywords | bmp6, vgr, tgf-beta ligand, chondrogenesis, cleavage on pair of basic residues, cytokine, developmental protein, differentiation, glycoprotein, growth factor, osteogenesis, secreted |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted : P22004 |
| Total number of polymer chains | 2 |
| Total formula weight | 27047.68 |
| Authors | Mueller, T.D.,Sebald, W. (deposition date: 2007-09-03, release date: 2008-01-15, Last modification date: 2023-08-30) |
| Primary citation | Saremba, S.,Nickel, J.,Seher, A.,Kotzsch, A.,Sebald, W.,Mueller, T.D. Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand. Febs J., 275:172-183, 2007 Cited by PubMed: 18070108DOI: 10.1111/j.1742-4658.2007.06187.x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report
