4QUO
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![BU of 4quo by Molmil](/molmil-images/mine/4quo) | Crystal structure of Aminopeptidase N in complex with the phosphinic dipeptide analogue LL-(R,S)-hPheP[CH2]Phe(3-CH2NH2) | 分子名称: | (2S)-2-[3-(aminomethyl)benzyl]-3-[(R)-[(1R)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]propanoic acid, Aminopeptidase N, GLYCEROL, ... | 著者 | Nocek, B, Mulligan, R, Joachimiak, A, Vassiliou, S, Berlicki, L, Mucha, A. | 登録日 | 2014-07-11 | 公開日 | 2014-09-10 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases. J.Med.Chem., 57, 2014
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5DYF
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![BU of 5dyf by Molmil](/molmil-images/mine/5dyf) | The crystal structure of Aminopeptidase N in complex with N-benzyl-1,2-diaminoethylphosphonic acid | 分子名称: | Aminopeptidase N, GLYCEROL, IMIDAZOLE, ... | 著者 | Nocek, B, Joachimiak, A, Vassiliou, S, Berlicki, L, Mucha, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-09-24 | 公開日 | 2015-11-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.854 Å) | 主引用文献 | The crystal structure of Aminopeptidase N in complex with N-benzyl-1,2-diaminoethylphosphonic acid To Be Published
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2B0P
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![BU of 2b0p by Molmil](/molmil-images/mine/2b0p) | truncated S. aureus LytM, P212121 crystal form | 分子名称: | ACETATE ION, CACODYLATE ION, Glycyl-glycine endopeptidase lytM, ... | 著者 | Firczuk, M, Mucha, A, Bochtler, M. | 登録日 | 2005-09-14 | 公開日 | 2006-01-10 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structures of active LytM. J.Mol.Biol., 354, 2005
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2B13
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![BU of 2b13 by Molmil](/molmil-images/mine/2b13) | Truncated S. aureus LytM, P41 crystal form | 分子名称: | Glycyl-glycine endopeptidase lytM, L(+)-TARTARIC ACID, ZINC ION | 著者 | Firczuk, M, Mucha, A, Bochtler, M. | 登録日 | 2005-09-15 | 公開日 | 2006-01-10 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structures of active LytM. J.Mol.Biol., 354, 2005
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2B44
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![BU of 2b44 by Molmil](/molmil-images/mine/2b44) | Truncated S. aureus LytM, P 32 2 1 crystal form | 分子名称: | Glycyl-glycine endopeptidase lytM, PHOSPHATE ION, ZINC ION | 著者 | Firczuk, M, Mucha, A, Bochtler, M. | 登録日 | 2005-09-22 | 公開日 | 2006-01-10 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Crystal structures of active LytM. J.Mol.Biol., 354, 2005
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4PU2
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![BU of 4pu2 by Molmil](/molmil-images/mine/4pu2) | Crystal structure of Aminopeptidase N in complex with the phosphonic acid analogue of leucine L-(R)-LeuP | 分子名称: | Aminopeptidase N, GLYCEROL, LEUCINE PHOSPHONIC ACID, ... | 著者 | Nocek, B, Vassiliou, S, Berlicki, L, Mulligan, R, Mucha, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-03-11 | 公開日 | 2014-06-25 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.095 Å) | 主引用文献 | Crystal structure of Aminopeptidase N in complex with the phosphonic acid analogue of leucine To be Published
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4PW4
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![BU of 4pw4 by Molmil](/molmil-images/mine/4pw4) | Crystal structure of Aminopeptidase N in complex with phosphonic acid analogue of homophenylalanine L-(R)-hPheP | 分子名称: | Aminopeptidase N, GLYCEROL, IMIDAZOLE, ... | 著者 | Nocek, B, Mulligan, R, Vassiliou, S, Berlicki, L, Mucha, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-03-18 | 公開日 | 2014-06-25 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of Aminopeptidase N in complex with phosphonic analogs of homophenylalanine TO BE PUBLISHED
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4PVB
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![BU of 4pvb by Molmil](/molmil-images/mine/4pvb) | Crystal structure of Aminopeptidase N in complex with the phosphonic acid analogue of leucine (D-(S)-LeuP) | 分子名称: | Aminopeptidase N, PHOSPHATE ION, SULFATE ION, ... | 著者 | Nocek, B, Vassiliou, S, Berlicki, L, Mulligan, R, Mucha, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-03-16 | 公開日 | 2014-06-25 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of Aminopeptidase N in complex with the phosphonic acid analogue of leucine (D-(S)-LeuP) To be Published
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4QPE
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![BU of 4qpe by Molmil](/molmil-images/mine/4qpe) | Crystal structure of Aminopeptidase N in complex with N-cyclohexyl-1,2-diaminoethylphosphonic acid | 分子名称: | Aminopeptidase N, SULFATE ION, ZINC ION, ... | 著者 | Nocek, B, Mulligan, R, Berlicki, L, Vassilious, S, Mucha, A, Joachimiak, A. | 登録日 | 2014-06-23 | 公開日 | 2014-09-24 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.004 Å) | 主引用文献 | Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases. J.Med.Chem., 57, 2014
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4QME
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![BU of 4qme by Molmil](/molmil-images/mine/4qme) | Crystal structure of Aminopeptidase N in complex with the phosphinic dipeptide analogue LL-(R,S)-hPheP[CH2]Phe | 分子名称: | (2S)-3-[(S)-[(1R)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid, Aminopeptidase N, GLYCEROL, ... | 著者 | Nocek, B, Vassilious, S, Mulligan, R, Berlicki, L, Mucha, A, Joachimiak, A. | 登録日 | 2014-06-16 | 公開日 | 2014-10-01 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases. J.Med.Chem., 57, 2014
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4QIR
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![BU of 4qir by Molmil](/molmil-images/mine/4qir) | Crystal structure of Aminopeptidase N in complex with the phosphinic dipeptide analogue LL-(R,S)-2-(pyridin-3-yl)ethylGlyP[CH2]Phe | 分子名称: | 3-{[(R)-1-amino-3-(pyridin-3-yl)propyl](hydroxy)phosphoryl}-(S)-2-benzylpropanoic acid, Aminopeptidase N, GLYCEROL, ... | 著者 | Nocek, B, Joachimiak, A, Berlicki, L, Vassiliou, S, Mucha, A. | 登録日 | 2014-06-01 | 公開日 | 2014-09-24 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | 主引用文献 | Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases. J.Med.Chem., 57, 2014
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7ZCY
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![BU of 7zcy by Molmil](/molmil-images/mine/7zcy) | Sporosarcina pasteurii urease (SPU) co-crystallized in the presence of an Ebselen-derivative and bound to Se atoms | 分子名称: | 1,2-ETHANEDIOL, HYDROXIDE ION, N-(2-chloranyl-4-fluoranyl-phenyl)-2-selanyl-benzamide, ... | 著者 | Mazzei, L, Ciurli, S, Cianci, M. | 登録日 | 2022-03-29 | 公開日 | 2023-04-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Optimized Ebselen-Based Inhibitors of Bacterial Ureases with Nontypical Mode of Action. J.Med.Chem., 66, 2023
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3EBG
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![BU of 3ebg by Molmil](/molmil-images/mine/3ebg) | Structure of the M1 Alanylaminopeptidase from malaria | 分子名称: | GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ... | 著者 | McGowan, S, Porter, C.J, Buckle, A.M, Whisstock, J.C. | 登録日 | 2008-08-27 | 公開日 | 2009-01-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase Proc.Natl.Acad.Sci.USA, 106, 2009
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3EBH
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![BU of 3ebh by Molmil](/molmil-images/mine/3ebh) | Structure of the M1 Alanylaminopeptidase from malaria complexed with bestatin | 分子名称: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, GLYCEROL, M1 family aminopeptidase, ... | 著者 | McGowan, S, Porter, C.J, Buckle, A.M, Whisstock, J.C. | 登録日 | 2008-08-27 | 公開日 | 2009-01-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase Proc.Natl.Acad.Sci.USA, 106, 2009
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3EBI
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![BU of 3ebi by Molmil](/molmil-images/mine/3ebi) | Structure of the M1 Alanylaminopeptidase from malaria complexed with the phosphinate dipeptide analog | 分子名称: | (2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid, GLYCEROL, M1 family aminopeptidase, ... | 著者 | McGowan, S, Porter, C.J, Buckle, A.M, Whisstock, J.C. | 登録日 | 2008-08-27 | 公開日 | 2009-01-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase Proc.Natl.Acad.Sci.USA, 106, 2009
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6AQE
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![BU of 6aqe by Molmil](/molmil-images/mine/6aqe) | Crystal structure of PPK2 in complex with Mg ATP | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | 著者 | Nocek, B, Joachimiak, A, Yakunin, A. | 登録日 | 2017-08-19 | 公開日 | 2019-01-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.805 Å) | 主引用文献 | Structural Insights into Substrate Selectivity and Activity of Bacterial Polyphosphate Kinases Acs Catalysis, 8, 2018
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6ANH
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![BU of 6anh by Molmil](/molmil-images/mine/6anh) | |
6ANG
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![BU of 6ang by Molmil](/molmil-images/mine/6ang) | |
6AU0
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![BU of 6au0 by Molmil](/molmil-images/mine/6au0) | Crystal structure of PPK2 (Class III) in complex with bisphosphonate inhibitor (2-((3,5-dichlorophenyl)amino)ethane-1,1-diyl)diphosphonic acid | 分子名称: | GLYCEROL, Polyphosphate:AMP phosphotransferase, {[(3,5-dichlorophenyl)amino]methylene}bis(phosphonic acid) | 著者 | Nocek, B, Ruszkowski, M, Joachimiak, A, Berlicki, L, Yakunin, A. | 登録日 | 2017-08-29 | 公開日 | 2019-01-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Insights into Substrate Selectivity and Activity of Bacterial Polyphosphate Kinases Acs Catalysis, 8, 2018
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6AN9
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![BU of 6an9 by Molmil](/molmil-images/mine/6an9) | |
6B18
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![BU of 6b18 by Molmil](/molmil-images/mine/6b18) | Crystal structure of PPK3 Class III in complex with inhibitor | 分子名称: | GLYCEROL, PHOSPHATE ION, PPK3 Class III, ... | 著者 | Nocek, B, Ruszkowski, M, Berlicki, L, Joachimiak, A, Yakunin, A. | 登録日 | 2017-09-17 | 公開日 | 2019-01-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Insights into Substrate Selectivity and Activity of Bacterial Polyphosphate Kinases Acs Catalysis, 8, 2018
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6AQN
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![BU of 6aqn by Molmil](/molmil-images/mine/6aqn) | Crystal structure of PPK2 in complex with phosphonic acid inhibitor | 分子名称: | GLYCEROL, Polyphosphate:AMP phosphotransferase, S,R MESO-TARTARIC ACID, ... | 著者 | Nocek, B, Berlicki, l, Joachimiak, A, Yakunin, S. | 登録日 | 2017-08-20 | 公開日 | 2019-01-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | 主引用文献 | Structural Insights into Substrate Selectivity and Activity of Bacterial Polyphosphate Kinases Acs Catalysis, 8, 2018
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3KQX
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![BU of 3kqx by Molmil](/molmil-images/mine/3kqx) | Structure of a protease 1 | 分子名称: | CARBONATE ION, M17 leucyl aminopeptidase, NONAETHYLENE GLYCOL, ... | 著者 | McGowan, S, Whisstock, J.C. | 登録日 | 2009-11-17 | 公開日 | 2010-02-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases Proc.Natl.Acad.Sci.USA, 107, 2010
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3KQZ
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![BU of 3kqz by Molmil](/molmil-images/mine/3kqz) | Structure of a protease 2 | 分子名称: | CARBONATE ION, M17 leucyl aminopeptidase, NONAETHYLENE GLYCOL, ... | 著者 | McGowan, S, Whisstock, J.C. | 登録日 | 2009-11-17 | 公開日 | 2010-02-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases Proc.Natl.Acad.Sci.USA, 107, 2010
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3KR4
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![BU of 3kr4 by Molmil](/molmil-images/mine/3kr4) | Structure of a protease 3 | 分子名称: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, CARBONATE ION, M17 leucyl aminopeptidase, ... | 著者 | McGowan, S, Whisstock, J.C. | 登録日 | 2009-11-17 | 公開日 | 2010-02-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases Proc.Natl.Acad.Sci.USA, 107, 2010
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