7ZCY
Sporosarcina pasteurii urease (SPU) co-crystallized in the presence of an Ebselen-derivative and bound to Se atoms
Summary for 7ZCY
| Entry DOI | 10.2210/pdb7zcy/pdb |
| Descriptor | Urease subunit gamma, Urease subunit beta, Urease subunit alpha, ... (10 entities in total) |
| Functional Keywords | urease, nickel, ebselen, selenium, hydrolase |
| Biological source | Sporosarcina pasteurii More |
| Total number of polymer chains | 3 |
| Total formula weight | 88870.41 |
| Authors | Mazzei, L.,Ciurli, S.,Cianci, M. (deposition date: 2022-03-29, release date: 2023-04-19, Last modification date: 2024-02-07) |
| Primary citation | Macegoniuk, K.,Tabor, W.,Mazzei, L.,Cianci, M.,Giurg, M.,Olech, K.,Burda-Grabowska, M.,Kaleta, R.,Grabowiecka, A.,Mucha, A.,Ciurli, S.,Berlicki, L. Optimized Ebselen-Based Inhibitors of Bacterial Ureases with Nontypical Mode of Action. J.Med.Chem., 66:2054-2063, 2023 Cited by PubMed: 36661843DOI: 10.1021/acs.jmedchem.2c01799 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.54 Å) |
Structure validation
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