1ZMR
| Crystal Structure of the E. coli Phosphoglycerate Kinase | 分子名称: | CALCIUM ION, Phosphoglycerate kinase | 著者 | Marqusee, S. | 登録日 | 2005-05-10 | 公開日 | 2006-05-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Comparison of proteolytic susceptibility in phosphoglycerate kinases from yeast and E. coli: modulation of conformational ensembles without altering structure or stability. J.Mol.Biol., 368, 2007
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8TQO
| Eukaryotic translation initiation factor 2B tetramer | 分子名称: | Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, Translation initiation factor eIF-2B subunit epsilon, ... | 著者 | Wang, L, Lawrence, R, Sangwan, S, Anand, A, Shoemaker, S, Deal, A, Marqusee, S, Watler, P. | 登録日 | 2023-08-08 | 公開日 | 2023-12-06 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling. Nat.Chem.Biol., 20, 2024
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8TQZ
| Eukaryotic translation initiation factor 2B with a mutation (L516A) in the delta subunit | 分子名称: | Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ... | 著者 | Wang, L, Lawrence, R, Sangwan, S, Anand, A, Shoemaker, S, Deal, A, Marqusee, S, Watler, P. | 登録日 | 2023-08-08 | 公開日 | 2023-12-06 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling. Nat.Chem.Biol., 20, 2024
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4LY7
| Ancestral RNase H | 分子名称: | Ribonuclease H, SULFATE ION | 著者 | Hart, K.M, Harms, M.J, Schmidt, B.H, Elya, C, Thornton, J.W, Marqusee, S. | 登録日 | 2013-07-30 | 公開日 | 2014-11-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Thermodynamic system drift in protein evolution. Plos Biol., 12, 2014
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3H08
| Crystal structure of the Ribonuclease H1 from Chlorobium tepidum | 分子名称: | MAGNESIUM ION, Rnh (Ribonuclease H) | 著者 | Ratcliff, K, Corn, J, Marqusee, S. | 登録日 | 2009-04-08 | 公開日 | 2009-05-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure, stability, and folding of ribonuclease H1 from the moderately thermophilic chlorobium tepidum: comparison with thermophilic and mesophilic homologues. Biochemistry, 48, 2009
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7UI5
| Evolution avoids a pathological stabilizing interaction in the immune protein S100A9 | 分子名称: | CALCIUM ION, Protein S100-A9 | 著者 | Reardon, P.N, Harman, J.L, Costello, S.M, Warren, G.D, Phillips, S.R, Connor, P.J, Marqusee, S, Harms, M.J. | 登録日 | 2022-03-28 | 公開日 | 2022-10-26 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Evolution avoids a pathological stabilizing interaction in the immune protein S100A9. Proc.Natl.Acad.Sci.USA, 119, 2022
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1JXB
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1JL2
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2II0
| Crystal Structure of catalytic domain of Son of sevenless (Rem-Cdc25) in the absence of Ras | 分子名称: | Son of sevenless homolog 1 | 著者 | Freedman, T.S, Sondermann, H, Friedland, G.D, Kortemme, T, Bar-Sagi, D, Marqusee, S, Kuriyan, J. | 登録日 | 2006-09-27 | 公開日 | 2006-10-31 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | A Ras-induced conformational switch in the Ras activator Son of sevenless. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1JL1
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2O79
| T4 lysozyme with C-terminal extension | 分子名称: | CHLORIDE ION, GLYCEROL, Lysozyme, ... | 著者 | Llinas, M, Crowder, S.M, Echols, N, Alber, T, Marqusee, S. | 登録日 | 2006-12-10 | 公開日 | 2007-04-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Exploring subdomain cooperativity in T4 lysozyme I: Structural and energetic studies of a circular permutant and protein fragment. Protein Sci., 16, 2007
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2O4W
| T4 lysozyme circular permutant | 分子名称: | CHLORIDE ION, Lysozyme | 著者 | Llinas, M, Crowder, S.M, Echols, N, Alber, T, Marqusee, S. | 登録日 | 2006-12-05 | 公開日 | 2007-04-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Exploring subdomain cooperativity in T4 lysozyme I: Structural and energetic studies of a circular permutant and protein fragment. Protein Sci., 16, 2007
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1DOF
| THE CRYSTAL STRUCTURE OF ADENYLOSUCCINATE LYASE FROM PYROBACULUM AEROPHILUM: INSIGHTS INTO THERMAL STABILITY AND HUMAN PATHOLOGY | 分子名称: | ADENYLOSUCCINATE LYASE | 著者 | Toth, E.A, Yeates, T.O, Goedken, E, Dixon, J.E, Marqusee, S. | 登録日 | 1999-12-20 | 公開日 | 2001-01-10 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds. J.Mol.Biol., 301, 2000
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1G15
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1F21
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6UEW
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6XHZ
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7SA7
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2O7A
| T4 lysozyme C-terminal fragment | 分子名称: | ACETATE ION, CHLORIDE ION, Lysozyme | 著者 | Echols, N, Kwon, E, Marqusee, S.M, Alber, T. | 登録日 | 2006-12-10 | 公開日 | 2007-04-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (0.84 Å) | 主引用文献 | Exploring subdomain cooperativity in T4 lysozyme I: Structural and energetic studies of a circular permutant and protein fragment. Protein Sci., 16, 2007
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8T8M
| Quis-bound intermediate mGlu5 | 分子名称: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Metabotropic glutamate receptor 5, Nb43 | 著者 | Krishna Kumar, K, Wang, H, Kobilka, B.K. | 登録日 | 2023-06-22 | 公開日 | 2023-10-11 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Stepwise activation of a metabotropic glutamate receptor. Nature, 629, 2024
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8T6J
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8T7H
| Quis-bound intermediate mGlu5 | 分子名称: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Metabotropic glutamate receptor 5, Nanobody 43 | 著者 | Krishna Kumar, K, Wang, H, Kobilka, B.K. | 登録日 | 2023-06-20 | 公開日 | 2023-10-11 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Stepwise activation of a metabotropic glutamate receptor. Nature, 629, 2024
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8TAO
| Quis and CDPPB bound active mGlu5 | 分子名称: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide, Metabotropic glutamate receptor 5, ... | 著者 | Krishna Kumar, K, Wang, H, Kobilka, B.K. | 登録日 | 2023-06-27 | 公開日 | 2023-10-11 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Stepwise activation of a metabotropic glutamate receptor. Nature, 629, 2024
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8FU6
| GCGR-Gs complex in the presence of RAMP2 | 分子名称: | Glucagon derivative ZP3780, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Krishna Kumar, K, O'Brien, E.S, Wang, H, Montabana, E, Kobilka, B.K. | 登録日 | 2023-01-16 | 公開日 | 2023-04-12 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Negative allosteric modulation of the glucagon receptor by RAMP2. Cell, 186, 2023
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4Z0U
| RNase HI/SSB-Ct complex | 分子名称: | Ribonuclease H, SSB-Ct Peptide | 著者 | Petzold, C, Keck, J.L. | 登録日 | 2015-03-26 | 公開日 | 2015-04-29 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Interaction with Single-stranded DNA-binding Protein Stimulates Escherichia coli Ribonuclease HI Enzymatic Activity. J.Biol.Chem., 290, 2015
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