2II0

Crystal Structure of catalytic domain of Son of sevenless (Rem-Cdc25) in the absence of Ras

Summary for 2II0

Entry DOI	10.2210/pdb2ii0/pdb
Related	1BKD 1NVV
Descriptor	Son of sevenless homolog 1 (2 entities in total)
Functional Keywords	signaling protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	57376.64
Authors	Freedman, T.S.,Sondermann, H.,Friedland, G.D.,Kortemme, T.,Bar-Sagi, D.,Marqusee, S.,Kuriyan, J. (deposition date: 2006-09-27, release date: 2006-10-31, Last modification date: 2023-08-30)
Primary citation	Freedman, T.S.,Sondermann, H.,Friedland, G.D.,Kortemme, T.,Bar-Sagi, D.,Marqusee, S.,Kuriyan, J. A Ras-induced conformational switch in the Ras activator Son of sevenless. Proc.Natl.Acad.Sci.Usa, 103:16692-16697, 2006 Cited by PubMed: 17075039 DOI: 10.1073/pnas.0608127103 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.02 Å)

Structure validation