2G04
 
 | | Crystal structure of fatty acid-CoA racemase from Mycobacterium tuberculosis H37Rv | | 分子名称: | PROBABLE FATTY-ACID-CoA RACEMASE FAR | | 著者 | Lee, K.S, Park, S.M, Rhee, K.H, Bang, W.G, Hwang, K.Y, Chi, Y.M. | | 登録日 | 2006-02-11 | | 公開日 | 2007-01-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of fatty acid-CoA racemase from Mycobacterium tuberculosis H37Rv
Proteins, 64, 2006
|
|
2Z3X
 | |
4OCZ
 | | Crystal structure of human soluble epoxide hydrolase complexed with 1-(1-isobutyrylpiperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea | | 分子名称: | 1-[1-(2-methylpropanoyl)piperidin-4-yl]-3-[4-(trifluoromethyl)phenyl]urea, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... | | 著者 | Lee, K.S.S, Liu, J, Wagner, K.M, Pakhomova, S, Dong, H, Morriseau, C, Fu, S.H, Yang, J, Wang, P, Ulu, A, Mate, C, Nguyen, L, Wullf, H, Eldin, M.L, Mara, A.A, Newcomer, M.E, Zeldin, D.C, Hammock, B.D. | | 登録日 | 2014-01-09 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy.
J.Med.Chem., 57, 2014
|
|
4OD0
 | | Crystal structure of human soluble epoxide hydrolase complexed with 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea | | 分子名称: | 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... | | 著者 | Lee, K.S.S, Liu, J, Wagner, K.M, Pakhomova, S, Dong, H, Morisseau, C, Fu, S.H, Yang, J, Wang, P, Ulu, A, Mate, C, Nguyen, L, Wullf, H, Eldin, M.L, Mara, A.A, Newcomer, M.E, Zeldin, D.C, Hammock, B.D. | | 登録日 | 2014-01-09 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy.
J.Med.Chem., 57, 2014
|
|
6CSV
 | | The structure of the Cep63-Cep152 heterotetrameric complex | | 分子名称: | Centrosomal protein of 63 kDa,Centrosomal protein of 152 kDa | | 著者 | Lee, E, Chen, Y, Zhang, L, Kim, T.S, Ahn, J.I, Park, J.E, Lee, K.S. | | 登録日 | 2018-03-21 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular architecture of a cylindrical self-assembly at human centrosomes.
Nat Commun, 10, 2019
|
|
6CSU
 | | The structure of the Cep63-Cep152 heterotetrameric complex | | 分子名称: | Centrosomal protein of 152 kDa, Centrosomal protein of 63 kDa | | 著者 | Lee, E, Chen, Y, Zhang, L, Kim, T.S, Ahn, J.I, Park, J.E, Lee, K.S. | | 登録日 | 2018-03-21 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular architecture of a cylindrical self-assembly at human centrosomes.
Nat Commun, 10, 2019
|
|
4O6W
 | | Peptide-Based Inhibitors of Plk1 Polo-box Domain | | 分子名称: | Peptide-Based inhibitor, Serine/threonine-protein kinase PLK1 | | 著者 | Qian, W.-J, Park, J.-E, Lim, D.C, Park, S.-Y, Lee, K.-W, Yaffe, M.B, Lee, K.S, Burke, T.R. | | 登録日 | 2013-12-23 | | 公開日 | 2014-12-03 | | 実験手法 | X-RAY DIFFRACTION (1.448 Å) | | 主引用文献 | Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in hela cells.
Biopolymers, 102, 2014
|
|
8CRC
 | | Structure of human Plk1 PBD in complex with Allopole-A | | 分子名称: | 7-chloro-4-(cyclopropylmethyl)-1-thioxo-2,4-dihydrothieno[2,3-e][1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one, GLYCEROL, Serine/threonine-protein kinase PLK1 | | 著者 | Kirsch, K, Park, J.E, Lee, K.S. | | 登録日 | 2023-03-08 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Specific inhibition of an anticancer target, polo-like kinase 1, by allosterically dismantling its mechanism of substrate recognition.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
4N7Z
 | | Crystal structure of human Plk4 cryptic polo box (CPB) in complex with a Cep192 N-terminal fragment | | 分子名称: | Centrosomal protein of 192 kDa, Serine/threonine-protein kinase PLK4 | | 著者 | Park, S.-Y, Park, J.-E, Tian, L, Kim, T.-S, Yang, W, Lee, K.S. | | 登録日 | 2013-10-16 | | 公開日 | 2014-07-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.
Nat.Struct.Mol.Biol., 21, 2014
|
|
4N9J
 | | Crystal structure of the cryptic polo box domain of human Plk4 | | 分子名称: | CHLORIDE ION, SULFATE ION, Serine/threonine-protein kinase PLK4 | | 著者 | Ku, B, Kim, J.H, Lee, K.S, Kim, S.J. | | 登録日 | 2013-10-21 | | 公開日 | 2014-07-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | | 主引用文献 | Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.
Nat.Struct.Mol.Biol., 21, 2014
|
|
4YWU
 | | Structural insight into the substrate inhibition mechanism of NADP+-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes | | 分子名称: | 4-oxobutanoic acid, SULFATE ION, Succinic semialdehyde dehydrogenase | | 著者 | Jang, E.H, Park, S.A, Chi, Y.M, Lee, K.S. | | 登録日 | 2015-03-21 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insight into the substrate inhibition mechanism of NADP(+)-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes.
Biochem.Biophys.Res.Commun., 461, 2015
|
|
4N7V
 | | Crystal structure of human Plk4 cryptic polo box (CPB) in complex with a Cep152 N-terminal fragment | | 分子名称: | Centrosomal protein of 152 kDa, Serine/threonine-protein kinase PLK4 | | 著者 | Park, S.-Y, Park, J.-E, Tian, L, Kim, T.-S, Yang, W, Lee, K.S. | | 登録日 | 2013-10-16 | | 公開日 | 2014-07-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.758 Å) | | 主引用文献 | Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.
Nat.Struct.Mol.Biol., 21, 2014
|
|
4YWV
 | | Structural insight into the substrate inhibition mechanism of NADP+-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes | | 分子名称: | 4-oxobutanoic acid, SULFATE ION, Succinic semialdehyde dehydrogenase | | 著者 | Park, S.A, Jang, E.H, Chi, Y.M, Lee, K.S. | | 登録日 | 2015-03-21 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insight into the substrate inhibition mechanism of NADP(+)-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes.
Biochem.Biophys.Res.Commun., 461, 2015
|
|
4E7P
 | | Crystal structure of receiver domain of putative NarL family response regulator spr1814 from Streptococcus pneumoniae in the presence of the phosphoryl analog beryllofluoride | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Response regulator | | 著者 | Park, A.K, Moon, J.H, Lee, K.S, Chi, Y.M. | | 登録日 | 2012-03-18 | | 公開日 | 2012-05-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.892 Å) | | 主引用文献 | Crystal structure of receiver domain of putative NarL family response regulator spr1814 from Streptococcus pneumoniae in the absence and presence of the phosphoryl analog beryllofluoride.
Biochem.Biophys.Res.Commun., 421, 2012
|
|
4E7O
 | | Crystal structure of receiver domain of putative NarL family response regulator spr1814 from Streptococcus pneumoniae | | 分子名称: | MAGNESIUM ION, Response regulator | | 著者 | Park, A.K, Moon, J.H, Lee, K.S, Chi, Y.M. | | 登録日 | 2012-03-18 | | 公開日 | 2012-05-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | | 主引用文献 | Crystal structure of receiver domain of putative NarL family response regulator spr1814 from Streptococcus pneumoniae in the absence and presence of the phosphoryl analog beryllofluoride.
Biochem.Biophys.Res.Commun., 421, 2012
|
|
4DFW
 | | Oxime-based Post Solid-phase Peptide Diversification: Identification of High Affinity Polo-like Kinase 1 (Plk1) Polo-box Domain Binding Peptides | | 分子名称: | CHLORIDE ION, Peptide, Serine/threonine-protein kinase PLK1 | | 著者 | Liu, F, Park, J.-E, Qian, W.-J, Lim, D, Gr ber, M, Berg, T, Yaffe, M.B, Lee, K.S, Burke Jr, T.R. | | 登録日 | 2012-01-24 | | 公開日 | 2012-03-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Oxime-based Post Solid-phase Peptide Diversification: Identification of High Affinity Polo-like Kinase 1 (Plk1) Polo-box Domain Binding Peptides
Chem.Biol., 2012
|
|
4OHT
 | | Crystal structure of succinic semialdehyde dehydrogenase from Streptococcus pyogenes in complex with NADP+ as the cofactor | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Succinate-semialdehyde dehydrogenase | | 著者 | Park, S.A, Jang, E.H, Chi, Y.M, Lee, K.S. | | 登録日 | 2014-01-18 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Kinetic and Structural Characterization for Cofactor Preference of Succinic Semialdehyde Dehydrogenase from Streptococcus pyogenes.
Mol.Cells, 37, 2014
|
|
9FLW
 | | CryoEM structure of the fragment-6 (3571-4078) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-06-05 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy
Science, 2024
|
|
9FLU
 | | CryoEM structure of the fragment-1 (3402-3733) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-06-05 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy
Science, 2024
|
|
9FLX
 | | CryoEM structure of the fragment-4 (4074-4421) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-06-05 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy
Science, 2024
|
|
9FLV
 | | CryoEM structure of the fragment-5 (2393-2807) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-06-05 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy
Science, 2024
|
|
9FLS
 | | CryoEM structure of the fragment-3 (2061-2397) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-06-05 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy
Science, 2024
|
|
9FLP
 | | CryoEM structure of the neck (1403-2314) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-06-05 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy
Science, 2024
|
|
9FLY
 | | CryoEM structure of the base (4151-5009) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-06-05 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy
Science, 2024
|
|
9G8B
 | | CryoEM structure of the fragment-2 (2892-3236) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 分子名称: | The grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | 著者 | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | 登録日 | 2024-07-23 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Mechanism of bacterial predation via ixotrophy
To Be Published
|
|
