4YWV

Structural insight into the substrate inhibition mechanism of NADP+-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes

Summary for 4YWV

Entry DOI	10.2210/pdb4ywv/pdb
Related	4OGD 4OHT 4YWU
Descriptor	Succinic semialdehyde dehydrogenase, 4-oxobutanoic acid, SULFATE ION, ... (4 entities in total)
Functional Keywords	succinic semialdehyde dehydrogenase, streptococcus pyogenes, substrate inhibition, ess-complex structure, oxidoreductase
Biological source	Streptococcus pyogenes MGAS1882
Total number of polymer chains	2
Total formula weight	104419.00
Authors	Park, S.A.,Jang, E.H.,Chi, Y.M.,Lee, K.S. (deposition date: 2015-03-21, release date: 2015-05-06, Last modification date: 2023-11-08)
Primary citation	Jang, E.H.,Park, S.A.,Chi, Y.M.,Lee, K.S. Structural insight into the substrate inhibition mechanism of NADP(+)-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes. Biochem.Biophys.Res.Commun., 461:487-493, 2015 Cited by PubMed: 25888791 DOI: 10.1016/j.bbrc.2015.04.047 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation