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4YWV

Structural insight into the substrate inhibition mechanism of NADP+-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Succinic semialdehyde dehydrogenasepolymer46551861.22UniProt (by SIFTS) (A0A0J9X1M8)Streptococcus pyogenes MGAS1882Succinate-semialdehyde dehydrogenase, NADP+-dependent succinic semialdehyde dehydrogenase
2C, D, G, H
(A, B)
4-oxobutanoic acidnon-polymer102.14Chemie (SSN)
3E, F, I
(A, B)
SULFATE IONnon-polymer96.13Chemie (SO4)
4J, K
(A, B)
waterwater18.0429Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight103722.5
Non-Polymers*Number of molecules7
Total formula weight696.5
All*Total formula weight104419.0
*Water molecules are not included.

249697

PDB entries from 2026-02-25

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