6O6O
 
 | | Structure of the regulator FasR from Mycobacterium tuberculosis | | 分子名称: | MYRISTIC ACID, TetR family transcriptional regulator | | 著者 | Larrieux, N, Trajtenberg, F, Lara, J, Gramajo, H, Buschiazzo, A. | | 登録日 | 2019-03-07 | | 公開日 | 2020-03-11 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine.
Nat Commun, 11, 2020
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6O6N
 | | Structure of the regulator FasR from Mycobacterium tuberculosis in complex with C20-CoA | | 分子名称: | Arachinoyl-CoA, CHLORIDE ION, TetR family transcriptional regulator | | 著者 | Larrieux, N, Trajtenberg, F, Lara, J, Gramajo, H, Buschiazzo, A. | | 登録日 | 2019-03-07 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine.
Nat Commun, 11, 2020
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6O6P
 | | Structure of the regulator FasR from Mycobacterium tuberculosis in complex with DNA | | 分子名称: | DNA-forward, DNA-reverse, TetR family transcriptional regulator | | 著者 | Larrieux, N, Trajtenberg, F, Lara, J, Gramajo, H, Buschiazzo, A. | | 登録日 | 2019-03-07 | | 公開日 | 2020-03-11 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.851 Å) | | 主引用文献 | Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine.
Nat Commun, 11, 2020
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1SVI
 | | Crystal Structure of the GTP-binding protein YsxC complexed with GDP | | 分子名称: | GTP-binding protein YSXC, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Ruzheinikov, S.N, Das, S.K, Sedelnikova, S.E, Baker, P.J, Artymiuk, P.J, Garcia-Lara, J, Foster, S.J, Rice, D.W. | | 登録日 | 2004-03-29 | | 公開日 | 2004-05-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Analysis of the Open and Closed Conformations of the GTP-binding Protein YsxC from Bacillus subtilis.
J.Mol.Biol., 339, 2004
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1SVW
 | | Crystal Structure of YsxC complexed with GMPPNP | | 分子名称: | GTP-binding protein YsxC, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | | 著者 | Ruzheinikov, S.N, Das, S.K, Sedelnikova, S.E, Baker, P.J, Artymiuk, P.J, Garcia-Lara, J, Foster, S.J, Rice, D.W. | | 登録日 | 2004-03-30 | | 公開日 | 2004-05-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Analysis of the Open and Closed Conformations of the GTP-binding Protein YsxC from Bacillus subtilis.
J.Mol.Biol., 339, 2004
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1SUL
 | | Crystal Structure of the apo-YsxC | | 分子名称: | GTP-binding protein YsxC | | 著者 | Ruzheinikov, S.N, Das, K.S, Sedelnikova, S.E, Baker, P.J, Artymiuk, P.J, Garcia-Lara, J, Foster, S.J, Rice, D.W. | | 登録日 | 2004-03-26 | | 公開日 | 2004-05-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Analysis of the Open and Closed Conformations of the GTP-binding Protein YsxC from Bacillus subtilis.
J.Mol.Biol., 339, 2004
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8TUP
 | | Cryo-EM structure of the human MRS2 magnesium channel under Mg2+-free condition | | 分子名称: | MAGNESIUM ION, Magnesium transporter MRS2 homolog, mitochondrial | | 著者 | Lai, L.T.F, Balaraman, J, Zhou, F, Matthies, D. | | 登録日 | 2023-08-16 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms.
Nat Commun, 14, 2023
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8TUL
 | | Cryo-EM structure of the human MRS2 magnesium channel under Mg2+ condition | | 分子名称: | MAGNESIUM ION, Magnesium transporter MRS2 homolog, mitochondrial | | 著者 | Lai, L.T.F, Balaraman, J, Zhou, F, Matthies, D. | | 登録日 | 2023-08-16 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms.
Nat Commun, 14, 2023
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8G83
 | | Structure of NAD+ consuming protein Acinetobacter baumannii TIR domain | | 分子名称: | NAD(+) hydrolase AbTIR | | 著者 | Klontz, E.H, Wang, Y, Glendening, G, Carr, J, Tsibouris, T, Buddula, S, Nallar, S, Soares, A, Snyder, G.A. | | 登録日 | 2023-02-17 | | 公開日 | 2023-10-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | The structure of NAD + consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations.
J.Biol.Chem., 299, 2023
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6NT2
 | | type 1 PRMT in complex with the inhibitor GSK3368715 | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, N~1~-({5-[4,4-bis(ethoxymethyl)cyclohexyl]-1H-pyrazol-4-yl}methyl)-N~1~,N~2~-dimethylethane-1,2-diamine, ... | | 著者 | Concha, N.O. | | 登録日 | 2019-01-28 | | 公開日 | 2019-07-10 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss.
Cancer Cell, 36, 2019
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4YDV
 | | STRUCTURE OF THE ANTIBODY 7B2 THAT CAPTURES HIV-1 VIRIONS | | 分子名称: | HIV ANTIBODY 7B2 HEAVY CHAIN,IgG H chain, HIV ANTIBODY 7B2 LIGHT CHAIN,Ig kappa chain C region, HIV GP41 PEPTIDE GP41(596-606) | | 著者 | Nicely, N.I, Pemble IV, C.W. | | 登録日 | 2015-02-23 | | 公開日 | 2015-08-12 | | 最終更新日 | 2021-03-24 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques.
Plos Pathog., 11, 2015
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6MFP
 | | Crystal Structure of the RV305 C1-C2 specific ADCC potent antibody DH677.3 Fab in complex with HIV-1 clade A/E gp120 and M48U1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Tolbert, W.D, Young, B, Pazgier, M. | | 登録日 | 2018-09-11 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Boosting with AIDSVAX B/E Enhances Env Constant Region 1 and 2 Antibody-Dependent Cellular Cytotoxicity Breadth and Potency.
J.Virol., 94, 2020
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6MFJ
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6VBP
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6VBQ
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6VBO
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4HPY
 | | Crystal structure of RV144-elicited antibody CH59 in complex with V2 peptide | | 分子名称: | CH59 Fab heavy chain, CH59 Fab light chain, Envelope glycoprotein gp160, ... | | 著者 | McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D. | | 登録日 | 2012-10-24 | | 公開日 | 2013-02-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
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4HPO
 | | Crystal structure of RV144-elicited antibody CH58 in complex with V2 peptide | | 分子名称: | CH58 Fab heavy chain, CH58 Fab light chain, Envelope glycoprotein gp160, ... | | 著者 | McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D. | | 登録日 | 2012-10-24 | | 公開日 | 2013-02-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.694 Å) | | 主引用文献 | Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
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5UIX
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4HQQ
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7N0X
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7N8Q
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7KCZ
 | | CRYSTAL STRUCTURE OF RHESUS MACAQUE (MACACA MULATTA) IGG1 FC FRAGMENT- FC-GAMMA RECEPTOR III COMPLEX V158 MUTANT | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IgG1 Fc, ... | | 著者 | Tolbert, W.D, Pazgier, M. | | 登録日 | 2020-10-07 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques.
Front Immunol, 13, 2022
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6MJ3
 | | CRYSTAL STRUCTURE OF RHESUS MACAQUE (MACACA MULATTA) IGG1 Fc Fragment-Fc-GAMMA RECEPTOR III complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Igg1 Fc, ... | | 著者 | Gohain, N, Tolbert, W.D, Pazgier, M. | | 登録日 | 2018-09-20 | | 公開日 | 2019-08-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques.
Front Immunol, 13, 2022
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6MJO
 | | CRYSTAL STRUCTURE OF RHESUS MACAQUE (MACACA MULATTA) FC-GAMMA RECEPTOR III | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Low affinity immunoglobulin gamma Fc region receptor III, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Van, V, Tolbert, W.D, Pazgier, M. | | 登録日 | 2018-09-21 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques.
Front Immunol, 13, 2022
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