7N8Q

Rhesusized RV305 DH677.3 Fab bound to Clade A/E 93TH057 HIV-1 gp120 core.

Summary for 7N8Q

• Entry DOI: 10.2210/pdb7n8q/pdb
• Descriptor: clade A/E 93TH057 HIV-1 gp120 core, M48U1 CD4 MIMETIC PEPTIDE, Rhesusized DH677.3 FAB HEAVY CHAIN, ... (6 entities in total)
• Functional Keywords: dh677.3, hiv-1 env v2 peptide, rv144, rv305, rhesusized antibody, immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 7
• Total formula weight: 181338.50

Authors

Tolbert, W.D.,Pazgier, M. (deposition date: 2021-06-15, release date: 2022-04-06, Last modification date: 2023-11-15)

• Primary citation: Tolbert, W.D.,Nguyen, D.N.,Tuyishime, M.,Crowley, A.R.,Chen, Y.,Jha, S.,Goodman, D.,Bekker, V.,Mudrak, S.V.,DeVico, A.L.,Lewis, G.K.,Theis, J.F.,Pinter, A.,Moody, M.A.,Easterhoff, D.,Wiehe, K.,Pollara, J.,Saunders, K.O.,Tomaras, G.D.,Ackerman, M.,Ferrari, G.,Pazgier, M.; Structure and Fc-Effector Function of Rhesusized Variants of Human Anti-HIV-1 IgG1s.; Front Immunol, 12:787603-787603, 2021; PubMed: 35069563; DOI: 10.3389/fimmu.2021.787603

Experimental method

X-RAY DIFFRACTION (2.9 Å)