7N8Q
Rhesusized RV305 DH677.3 Fab bound to Clade A/E 93TH057 HIV-1 gp120 core.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (G, A) | clade A/E 93TH057 HIV-1 gp120 core | polymer | 355 | 39356.6 | 2 | UniProt (A0A0M3KKW9) Pfam (PF00516) | Human immunodeficiency virus 1 | |
| 2 | B (N) | M48U1 CD4 MIMETIC PEPTIDE | polymer | 28 | 3056.8 | 1 | synthetic construct | ||
| 3 | C, F (H, C) | Rhesusized DH677.3 FAB HEAVY CHAIN | polymer | 228 | 24540.5 | 2 | Macaca mulatta | ||
| 4 | D, G (L, D) | Rhesusized DH677.3 FAB LIGHT CHAIN | polymer | 214 | 23252.8 | 2 | Macaca mulatta | ||
| 5 | H, I, J, K, L... (G, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 18 | Chemie (NAG) | |||
| 6 | AA, BA, CA, DA, EA... (H, L, A, C, D...) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
G, A: 44 - 492 (UniProt: A0A0M3KKW9)
| PDB | External Database | Details |
|---|---|---|
| Val 42 | - | expression tag |
| Pro 43 | - | expression tag |
| Ser 375 | His 242 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 177356.8 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3981.7 | |
| All* | Total formula weight | 181338.5 |
