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3EK9
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BU of 3ek9 by Molmil
SPRY Domain-containing SOCS Box Protein 2: Crystal Structure and Residues Critical for Protein Binding
分子名称: GLYCEROL, SPRY domain-containing SOCS box protein 2
著者Kuang, Z, Yao, S, Xu, Y, Garrett, T.J.P, Norton, R.S.
登録日2008-09-19
公開日2009-02-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献SPRY domain-containing SOCS box protein 2: crystal structure and residues critical for protein binding.
J.Mol.Biol., 386, 2009
2H7T
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BU of 2h7t by Molmil
Solution Structure of the C-terminal Domain of Insulin-like Growth Factor Binding Protein 2 (IGFBP-2)
分子名称: Insulin-like growth factor-binding protein 2
著者Kuang, Z.
登録日2006-06-03
公開日2007-04-24
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Structure, dynamics and heparin binding of the C-terminal domain of insulin-like growth factor-binding protein-2 (IGFBP-2)
J.Mol.Biol., 364, 2006
7EWF
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BU of 7ewf by Molmil
Selenomethionine-substituted structure of S. cerevisiae Csn12 in complex with Thp3 and Sem1
分子名称: 26S proteasome complex subunit SEM1, Cop9 signalosome complex subunit 12, Protein THP3
著者Kuang, Z, Niu, L.
登録日2021-05-25
公開日2022-09-07
最終更新日2023-04-05
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural assembly of the nucleic-acid-binding Thp3-Csn12-Sem1 complex functioning in mRNA splicing.
Nucleic Acids Res., 50, 2022
7EWM
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BU of 7ewm by Molmil
Native crystal structure of S. cerevisiae Csn12 in complex with Thp3 and Sem1
分子名称: 26S proteasome complex subunit SEM1, Cop9 signalosome complex subunit 12, Protein THP3
著者Kuang, Z, Niu, L.
登録日2021-05-25
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural assembly of the nucleic-acid-binding Thp3-Csn12-Sem1 complex functioning in mRNA splicing.
Nucleic Acids Res., 50, 2022
2LOC
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BU of 2loc by Molmil
Conotoxin analogue [D-Ala2]BuIIIB
分子名称: Mu-conotoxin BuIIIB
著者Kuang, Z.
登録日2012-01-21
公開日2013-01-23
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Mammalian neuronal sodium channel blocker mu-conotoxin BuIIIB has a structured N-terminus that influences potency.
Acs Chem.Biol., 8, 2013
2LO9
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BU of 2lo9 by Molmil
NMR solution structure of Mu-contoxin BuIIIB
分子名称: Mu-conotoxin BuIIIB
著者Kuang, Z.
登録日2012-01-20
公開日2013-01-23
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Mammalian neuronal sodium channel blocker mu-conotoxin BuIIIB has a structured N-terminus that influences potency.
Acs Chem.Biol., 8, 2013
8JAT
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BU of 8jat by Molmil
Crystal structure of the 3-ketodihydrosphingosine reductase TSC10 from Cryptococcus neoformans
分子名称: 3-ketodihydrosphingosine reductase TSC10, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhao, P, Kuang, Z.
登録日2023-05-07
公開日2023-06-21
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the 3-ketodihydrosphingosine reductase TSC10 from Cryptococcus neoformans.
Biochem.Biophys.Res.Commun., 670, 2023
5XN3
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BU of 5xn3 by Molmil
Crystal structure of SPSB2 in complex with a rational designed RGD containing cyclic peptide inhibitor of SPSB2-iNOS interaction
分子名称: SPRY domain-containing SOCS box protein 2, cR8 peptide from NOS2
著者You, T, Kuang, Z.
登録日2017-05-17
公開日2017-06-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Crystal structure of SPSB2 in complex with a rational designed RGD-containing cyclic peptide inhibitor of SPSB2-iNOS interaction.
Biochem. Biophys. Res. Commun., 489, 2017
6JKJ
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Crystal structure of human SPSB2 in the apo-state
分子名称: SPRY domain-containing SOCS box protein 2
著者Luo, Y, Kuang, Z.
登録日2019-03-01
公開日2019-07-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the SPRY domain of human SPSB2 in the apo state.
Acta Crystallogr.,Sect.F, 75, 2019
6JWN
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Crystal structure of the SPRY domain of SPSB2 in complex with cR9, a cyclic peptide inhibitor of SPSB-iNOS interaction
分子名称: Nitric oxide synthase, inducible, SPRY domain-containing SOCS box protein 2
著者Li, K, Kuang, Z.
登録日2019-04-21
公開日2020-04-22
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Crystal structure of SPSB2 in complex with cR9, a cyclic peptide inhibitor of SPSB-iNOS interaction
To Be Published
6KEY
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BU of 6key by Molmil
Structural basis for the regulation of inducible nitric oxide synthase (iNOS) by the SPRY domain-containing SOCS box protein 2 (SPSB2)
分子名称: Nitric oxide synthase, inducible, SPRY domain-containing SOCS box protein 2
著者Li, K, Kuang, Z.
登録日2019-07-05
公開日2020-07-01
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Structural basis for the regulation of inducible nitric oxide synthase by the SPRY domain-containing SOCS box protein SPSB2, an E3 ubiquitin ligase.
Nitric Oxide, 113-114, 2021
6JWM
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BU of 6jwm by Molmil
Crystal structure of the SPRY domain of SPSB2 in complex with cR7, a potent cyclic peptide inhibitor of SPSB2-iNOS interaction
分子名称: Nitric oxide synthase, inducible, SPRY domain-containing SOCS box protein 2
著者Li, K, Kuang, Z.
登録日2019-04-21
公開日2020-04-22
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Crystal structure of SPSB2 in complex with cR7, a potent cyclic peptide inhibitor of SPSB2-iNOS interaction
To Be Published
7CCB
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BU of 7ccb by Molmil
Crystal structure of the SPRY domain-containing protein 7 (SPRY7)
分子名称: SPRY domain-containing protein 7
著者Yang, J, Kuang, Z.
登録日2020-06-16
公開日2020-10-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Crystal structure of the SPRY domain-containing protein 7 reveals unique structural features.
Biochem.Biophys.Res.Commun., 531, 2020
3EMW
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BU of 3emw by Molmil
Crystal Structure of human splA/ryanodine receptor domain and SOCS box containing 2 (SPSB2) in complex with a 20-residue VASA peptide
分子名称: 1,2-ETHANEDIOL, Peptide (VASA), SPRY domain-containing SOCS box protein 2
著者Filippakopoulos, P, Sharpe, T, Keates, T, Murray, J.W, Savitsky, P, Roos, A.K, Pike, A.C.W, Von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Bullock, A, Structural Genomics Consortium (SGC)
登録日2008-09-25
公開日2008-10-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.
J.Mol.Biol., 401, 2010
6OM3
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BU of 6om3 by Molmil
Crystal structure of the Orc1 BAH domain in complex with a nucleosome core particle
分子名称: DNA (146-MER), DNA (147-MER), Histone H2A, ...
著者De Ioannes, P.E, Wang, M, Armache, K.-J.
登録日2019-04-18
公開日2019-07-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure and function of the Orc1 BAH-nucleosome complex.
Nat Commun, 10, 2019
3F2O
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BU of 3f2o by Molmil
Crystal Structure of human splA/ryanodine receptor domain and SOCS box containing 1 (SPSB1) in complex with a 20-residue VASA peptide
分子名称: 20-mer peptide from ATP-dependent RNA helicase vasa, SPRY domain-containing SOCS box protein 1
著者Filippakopoulos, P, Sharpe, T, Keates, T, Murray, J.W, Savitsky, P, Roos, A, Pike, A.C.W, Von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Bullock, A, Structural Genomics Consortium (SGC)
登録日2008-10-30
公開日2008-12-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.
J.Mol.Biol., 401, 2010
2V24
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Structure of the human SPRY domain-containing SOCS box protein SSB-4
分子名称: NICKEL (II) ION, SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 4
著者Uppenberg, J, Bullock, A, Keates, T, Savitsky, P, Pike, A.C.W, Ugochukwu, E, Bunkoczi, G, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Knapp, S.
登録日2007-05-31
公開日2007-07-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for Par-4 Recognition by the Spry Domain-and Socs Box-Containing Proteins Spsb1, Spsb2, and Spsb4.
J.Mol.Biol., 401, 2010
7FCP
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BU of 7fcp by Molmil
Crystallographic structure of two neutralizing antibodies in complex with SARS-CoV-2 spike receptor-binding Domain (RBD)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Zheng, P, Jin, T.
登録日2021-07-15
公開日2022-06-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Ultrapotent neutralizing antibodies against SARS-CoV-2 with a high degree of mutation resistance.
J.Clin.Invest., 132, 2022
7FCQ
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BU of 7fcq by Molmil
Crystallographic structure of neutralizing antibody P14-44 in complex with SARS-CoV-2 spike receptor-binding Domain (RBD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, P14-44 antibody Fab fragment heavy chain, ...
著者Zheng, P, Jin, T.
登録日2021-07-15
公開日2022-06-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Ultrapotent neutralizing antibodies against SARS-CoV-2 with a high degree of mutation resistance.
J.Clin.Invest., 132, 2022
8W2O
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Yeast U1 snRNP with humanized U1C Zinc-Finger domain
分子名称: 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA, Pre-mRNA-processing factor 39, ...
著者Shi, S.S, Kuang, Z.L, Zhao, R.
登録日2024-02-20
公開日2024-05-15
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Selected humanization of yeast U1 snRNP leads to global suppression of pre-mRNA splicing and mitochondrial dysfunction in the budding yeast.
Rna, 30, 2024
2JK9
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The structure of splA-ryanodine receptor domain and SOCS box containing 1 in complex with a PAR-4 peptide
分子名称: PRKC APOPTOSIS WT1 REGULATOR PROTEIN, SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 1
著者Filippakopoulos, P, Bullock, A, Keates, T, Savitsky, P, Murray, J.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Wickstroem, M, Bountra, C, Knapp, S.
登録日2008-08-22
公開日2008-09-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural Basis for Par-4 Recognition by the Spry Domain-and Socs Box-Containing Proteins Spsb1, Spsb2, and Spsb4.
J.Mol.Biol., 401, 2010
7D8F
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The crystal structure of ScNTM1 in complex with SAH
分子名称: Alpha N-terminal protein methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE
著者Zhang, H.Y, Yue, J, Zhu, Z.L.
登録日2020-10-08
公開日2021-05-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structural Basis for Peptide Binding of Alpha-N Terminal Methyltransferase from Saccharomyces cerevisiae
Crystallography Reports, 66, 2021
7D8D
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The crystal structure of ScNTM1 in complex with SAH and Rps25a hexapeptide
分子名称: Alpha N-terminal protein methyltransferase 1, Rps25A-peptide, S-ADENOSYL-L-HOMOCYSTEINE
著者Zhang, H.Y, Yue, J.
登録日2020-10-08
公開日2021-05-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Structural Basis for Peptide Binding of Alpha-N Terminal Methyltransferase from Saccharomyces cerevisiae
Crystallography Reports, 66, 2021
7DSJ
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Anthranilate phosphoribosyltransferase from Saccharomyces cerevisiae in complex with PRPP and Mg
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MAGNESIUM ION
著者Wu, X.
登録日2020-12-31
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Crystal structures of anthranilate phosphoribosyltransferase from Saccharomyces cerevisiae.
Acta Crystallogr.,Sect.F, 77, 2021
7DSM
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Anthranilate phosphoribosyltransferase from Saccharomyces cerevisiae
分子名称: Anthranilate phosphoribosyltransferase
著者Wu, X.
登録日2020-12-31
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal structures of anthranilate phosphoribosyltransferase from Saccharomyces cerevisiae.
Acta Crystallogr.,Sect.F, 77, 2021

 

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