2LOC

Conotoxin analogue [D-Ala2]BuIIIB

Summary for 2LOC

• Entry DOI: 10.2210/pdb2loc/pdb
• Related: 2LO9
• NMR Information: BMRB: 18206
• Descriptor: Mu-conotoxin BuIIIB (1 entity in total)
• Functional Keywords: d-amino acid substitution, toxin
• Biological source: Conus bullatus (Bubble cone)
• Cellular location: Secreted (By similarity): C1J5M6
• Total number of polymer chains: 1
• Total formula weight: 2790.31

Authors

Kuang, Z. (deposition date: 2012-01-21, release date: 2013-01-23, Last modification date: 2023-06-14)

• Primary citation: Kuang, Z.,Zhang, M.M.,Gupta, K.,Gajewiak, J.,Gulyas, J.,Balaram, P.,Rivier, J.E.,Olivera, B.M.,Yoshikami, D.,Bulaj, G.,Norton, R.S.; Mammalian neuronal sodium channel blocker mu-conotoxin BuIIIB has a structured N-terminus that influences potency.; Acs Chem.Biol., 8:1344-1351, 2013; PubMed: 23557677; DOI: 10.1021/cb300674x

Experimental method

SOLUTION NMR