3EMW

Crystal Structure of human splA/ryanodine receptor domain and SOCS box containing 2 (SPSB2) in complex with a 20-residue VASA peptide

Summary for 3EMW

• Entry DOI: 10.2210/pdb3emw/pdb
• Descriptor: SPRY domain-containing SOCS box protein 2, Peptide (VASA), 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: apoptosis nucleus, apoptosis, ubl conjugation pathwayc, cl transcription regulation, transcription, phosphoprotein, ubl conjugation pathway, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm (Probable): Q99619
• Total number of polymer chains: 2
• Total formula weight: 26595.60

Authors

Filippakopoulos, P.,Sharpe, T.,Keates, T.,Murray, J.W.,Savitsky, P.,Roos, A.K.,Pike, A.C.W.,Von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Bullock, A.,Structural Genomics Consortium (SGC) (deposition date: 2008-09-25, release date: 2008-10-28, Last modification date: 2023-11-01)

• Primary citation: Filippakopoulos, P.,Low, A.,Sharpe, T.D.,Uppenberg, J.,Yao, S.,Kuang, Z.,Savitsky, P.,Lewis, R.S.,Nicholson, S.E.,Norton, R.S.,Bullock, A.N.; Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.; J.Mol.Biol., 401:389-402, 2010; PubMed: 20561531; DOI: 10.1016/j.jmb.2010.06.017

Experimental method

X-RAY DIFFRACTION (1.8 Å)