3EMW

Crystal Structure of human splA/ryanodine receptor domain and SOCS box containing 2 (SPSB2) in complex with a 20-residue VASA peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	SPRY domain-containing SOCS box protein 2	polymer	217	23849.6	1	UniProt (Q99619) Pfam (PF00622) In PDB	Homo sapiens (Human)	SPSB2, SSB-2, Gene-rich cluster protein C9
2	B	Peptide (VASA)	polymer	20	2497.7	1	UniProt (by SIFTS) (P09052) In PDB
3	A	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
4		water	water		18.0	138	Chemie (HOH)

Sequence modifications

A: 26 - 219 (UniProt: Q99619)

PDB	External Database	Details
Met 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
Ser 10	-	expression tag
Ser 11	-	expression tag
Gly 12	-	expression tag
Val 13	-	expression tag
Asp 14	-	expression tag
Leu 15	-	expression tag
Gly 16	-	expression tag
Thr 17	-	expression tag
Glu 18	-	expression tag
Asn 19	-	expression tag
Leu 20	-	expression tag
Tyr 21	-	expression tag
Phe 22	-	expression tag
Gln 23	-	expression tag
Ser 24	-	expression tag
Met 25	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	26347.3
Non-Polymers*	Number of molecules	4
	Total formula weight	248.3
All*	Total formula weight	26595.6

*Water molecules are not included.